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Berman - Data simplification taming information with open source tools

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Data Simplification Taming Information With Open Source Tools First Edition - photo 1
Data Simplification
Taming Information With Open Source Tools

First Edition

Jules J. Berman

Copyright Morgan Kaufmann is an imprint of Elsevier 50 Hampshire Street 5th - photo 2

Copyright

Morgan Kaufmann is an imprint of Elsevier

50 Hampshire Street, 5th Floor, Cambridge, MA 02139, USA

Copyright 2016 Elsevier Inc. All rights reserved.

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publishers permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions.

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notices

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.

To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

British Library Cataloguing in Publication Data

A catalogue record for this book is available from the British Library

Library of Congress Cataloging-in-Publication Data

A catalog record for this book is available from the Library of Congress

ISBN: 978-0-12-803781-2

For information on all MK publications visit our website at https://www.elsevier.com/

Publisher Todd Green Acquisition Editor Todd Green Editorial Project - photo 3

Publisher: Todd Green

Acquisition Editor: Todd Green

Editorial Project Manager: Amy Invernizzi

Production Project Manager: Punithavathy Govindaradjane

Designer: Mark Rogers

Typeset by SPi Global, India

Dedication

For my best friend, Bailey.

Foreword

It is common knowledge that every computer scientist, programmer, statistician, informatician, and knowledge domain expert must know how to analyze data. It is less commonly known that very few of these data professionals are given the skills required to prepare their data in a form that supports credible analysis. As Berman points out, data analysis has no value unless it can be verified, validated, reanalyzed, and repurposed, as needed. Data Simplification: Taming Information with Open Source Tools is a practical guide to the messiness of complex and heterogeneous data used in discovery science (ie, our optimistic resolve to understand what our data is trying to tell us). Berman successfully makes the case for data simplification as a discipline within data science.

In this important work Berman deals with the practical aspects of complex data - photo 4

In this important work, Berman deals with the practical aspects of complex data sets and creates a workflow for tackling problems in so-called big data research. No book to date has effectively dealt with the sources of data complexity in such a comprehensive, yet practical fashion. Speaking from my own area of involvement, biomedical researchers wrestling with genome/imaging/computational phenotype analyses will find Berman's approach to data simplification particularly constructive.

The book opens with a convincing demonstration that complex data requires simplification in order to answer high impact questions. Berman shows that the process of data simplification is not, itself, simple. He provides a set of principles, methods and tools to unlock the secrets of big data. More importantly, he provides a roadmap to the use of free, open source tools in the data simplification process; skills that need to be emphasized to the data science community irrespective of scientific discipline. It is fair to acknowledge that our customary reliance on costly and comprehensive software/development solutions will sometimes increase the likelihood that a data project will fail.

As there is a gold rush encouraging the workforce training of data scientists, this gritty Rules of the Road monograph should serve as a constant companion for modern data scientists. Berman convincingly portrays the value of programmers and analysts who have facility with Perl, Python, or Ruby and who understand the critical role of metadata, indexing, and data visualization. These professionals will be high on my shopping list of talent to add to our biomedical informatics team in Pittsburgh.

Data science is currently the focus of an intense, worldwide effort extending to all biomedical institutions. It seems that we have reached a point where progress in the biomedical sciences is paused, waiting for us to draw useful meaning from the dizzying amount of new data being collected by high throughput technologies, electronic health records, mobile medical sensors, and the exabytes generated from imaging modalities in research and clinical practice. Here at the University of Pittsburgh, we are deeply involved in the efforts of the U.S. National Institutes of Health to tame complex biomedical data, through our membership in the NIH Big Data to Knowledge (BD2K) Consortium (https://datascience.nih.gov/bd2k). Our continuing fascination with more data and big data have been compounded by the amplification and hype of an array of software tools and solutions that claim to solve big data problems. Although, much of data science innovation focuses on hardware, cloud computing, and novel algorithms to solve BD2K problems, the critical issues remain at the level of the utility of the data (eg, simplification) addressed in this important book by Berman.

Data Simplification provides easy, free solutions to the unintended consequences of data complexity. This book should be the first (and probably most important) guide to success in the data sciences. I will be providing copies to my trainees, programmers, analysts, and faculty, as required reading.

Michael J. Becich, MD, PhD , Associate Vice-Chancellor for Informatics in the Health Sciences , Chairman and Distinguished University Professor, Department of Biomedical Informatics , Director, Center for Commercial Application (CCA) of Healthcare Data, University of Pittsburgh School of Medicine

Preface
Abstract

The purpose of the preface is to elevate data simplification to the level of a discipline within the general field of data science. Readers will learn that data simplification is at least as important as data analysis. Inadequate analyses can be reviewed and improved if the data is well-annotated and the data records are simple. Analytic tools are of little help if the data is complex and inscrutable. The preface will provide a very short introduction and take-home summary for the 8 book chapters, explaining how the methods described in each chapter fulfill a necessary component of data simplification. The following points will be developed: (1) Large and complex data cannot be explored unless data is simplified; (2) Data simplification is not simple; there are principles, methods, and tools that must be studied and mastered; (3) Data simplification tools become data discovery tools, in the hands of creative individuals; and (4) Learning the methods and tools of data simplification is a great career move.

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