Kapur Shitij - Schizophrenia : the final frontier : a festschrift for Robin M. Murray

THE MAUDSLEY

The Maudsley Series

The Maudsley Series

HENRY MAUDSLEY, from whom the series of monographs takes its name, was the founder of The Maudsley Hospital and the most prominent English psychiatrist of his generation. The Maudsley Hospital was united with the Bethlem Royal Hospital in 1948 and its medical school, renamed the Institute of Psychiatry at the same time, became a constituent part of the British Postgraduate Medical Federation. It is now a school of Kings College, London, and entrusted with the duty of advancing psychiatry by teaching and research. The South London & Maudsley NHS Trust, together with the Institute of Psychiatry, are jointly known as The Maudsley.

The monograph series reports high quality empirical work on a single topic of relevance to mental health, carried out at the Maudsley. This can be by single or multiple authors. Some of the monographs are directly concerned with clinical problems; others, are in scientific fields of direct or indirect relevance to mental health and that are cultivated for the furtherance of psychiatry.

Editor

Professor A. S. David MPhil MSc FRCP MRCPsych MD

Assistant Editor

Professor T. Wykes BSc PhD MPhil

Previous Editors

The Maudsley Series

Schizophrenia

The Final Frontier A Festschrift for Robin M. Murray

Edited by Anthony S. David, Shitij Kapur and Peter McGuffin

First published 2011

by Psychology Press

27 Church Road, Hove, East Sussex BN3 2FA

Simultaneously published in the USA and Canada

by Routledge

711 Third Avenue, New York, NY 10017

Psychology Press is an imprint of the Taylor & Francis Group, an Informa Business

Copyright 2011 Psychology Press

All rights reserved. No part of this book may be reprinted or reproduced or utilised in any form or by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers.

British Library Cataloguing in Publication Data

A catalogue record for this book is available from the British Library

Library of Congress Cataloguing-in-Publication Data

Schizophrenia : the final frontier : a festschrift for

Robin M. Murray / edited by Anthony S. David,

Shitij Kapur, and Peter McGuffin.

p. ; cm. (Maudsley series)

Includes bibliographical references and index.

ISBN 978-1-84872-077-0 (hbk)

1. Schizophrenia. I. David, Anthony S., editor. II. Kapur, Shitij, editor.

III. McGuffm, Peter, editor. IV. Murray, Robin M., 1944-, honoree.

V. Series: Maudsley series.

[DNLM: 1. Murray, Robin M., 1944-2. SchizophreniaFestschrift. WM 203]

RC514.S336445 2011

ISBN: 978-1-84872-077-0 (hbk)

ISBN: 978-0-203-80877-1 (ebk)

Plates

Colour section between pages 32 and 38

Figures

Tables

Contributors

Judith Allardyce, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK

Matt Allin, Institute of Psychiatry, Kings College London, London, UK

Paul Bebbington, Department of Mental Health Sciences, University College London, London, UK

Tejas Bhojraj, Harvard Medical School, Boston, MA, USA

Jane Boydell, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK

Elvira Bramon, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK

Ed Bullmore, Department of Psychiatry, University of Cambridge, Cambridge, UK

Tyrone D. Cannon, Departments of Psychology & Psychiatry & Behavioural Sciences, University of California, Los Angeles, CA, USA

Paola Casadio, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK

David J. Castle, University of Melbourne, Melbourne, Australia

Kodavali V. Chowdari, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

Tim J. Crow, SANE Prince of Wales International Centre, Warneford Hospital, Oxford, UK

Anthony S. David, Section of Cognitive Neuropsychiatry, Institute of Psychiatry, Kings College London, London, UK

Paola Dazzan, NIH Biomedical Research Centre, Institute of Psychiatry, Kings College London, London, UK

Marta Di Forti, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK

Graham Dunn, Community Based Medicine, Manchester University, Manchester, UK

Lauren M. Ellman, Departments of Psychology & Psychiatry & Behavioural Sciences, University of California, Los Angeles, CA, USA

Paul Fearon, St Patricks University Hospital and Trinity College Dublin, Dublin, Ireland

Daniel Freeman, Department of Psychology, Institute of Psychiatry, Kings College London, London, UK

Philippa Garety, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK

Paul J. Harrison, Department of Psychiatry, University of Oxford, Oxford, UK

Jari Haukka, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland

Sheilagh Hodgins, Department of Forensic Mental Health Science, Institute of Psychiatry, Kings College London, London, UK

Oliver D. Howes, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK

Gerard Hutchinson, Psychiatry Unit, University of the West Indies, Trinidad

Matti Isohanni, Department of Psychiatry, University of Oulu, Oulu, Finland

Suzanne Jolley, Department of Psychology, Institute of Psychiatry, Kings College London, London, UK

Peter B. Jones, Department of Psychological Medicine, University of Cambridge, Cambridge, UK

Shitij Kapur, Department of Psychological Medicine & Psychiatry, Institute of Psychiatry, Kings College, London, UK

Katherine H. Karlsgodt, Departments of Psychology & Psychiatry & Behavioural Sciences, University of California, Los Angeles, CA, USA

Matcheri S. Keshavan, Harvard Medical School Department of Psychiatry, Boston, MA, USA

Julia Lappin, Department of Psychosis Studies, Institute of Psychiatry, Kings College London, London, UK