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Robert Wilkins - Oxford Handbook of Medical Sciences

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OXFORD MEDICAL PUBLICATIONS Oxford Handbook of Medical Sciences Contents Guide - photo 1

OXFORD MEDICAL PUBLICATIONS
Oxford Handbook of
Medical Sciences

Contents
Guide
Page List

Published and forthcoming Oxford Medical Handbooks

Oxford Handbook for the Foundation Programme 3e

Oxford Handbook of Acute Medicine 3e

Oxford Handbook of Anaesthesia 3e

Oxford Handbook of Applied Dental Sciences

Oxford Handbook of Cardiology

Oxford Handbook of Clinical and Laboratory Investigation 2e

Oxford Handbook of Clinical Dentistry 5e

Oxford Handbook of Clinical Diagnosis 2e

Oxford Handbook of Clinical Examination and Practical Skills

Oxford Handbook of Clinical Haematology 3e

Oxford Handbook of Clinical Immunology and Allergy 2e

Oxford Handbook of Clinical Medicine - Mini Edition 8e

Oxford Handbook of Clinical Medicine 8e

Oxford Handbook of Clinical Pharmacy

Oxford Handbook of Clinical Rehabilitation 2e

Oxford Handbook of Clinical Specialties 8e

Oxford Handbook of Clinical Surgery 3e

Oxford Handbook of Complementary Medicine

Oxford Handbook of Critical Care 3e

Oxford Handbook of Dental Patient Care 2e

Oxford Handbook of Dialysis 3e

Oxford Handbook of Emergency Medicine 3e

Oxford Handbook of Endocrinology and Diabetes 2e

Oxford Handbook of ENT and Head and Neck Surgery

Oxford Handbook of Expedition and Wilderness Medicine

Oxford Handbook of Gastroenterology & Hepatology

Oxford Handbook of General Practice 3e

Oxford Handbook of Genetics

Oxford Handbook of Genitourinary Medicine, HIV and AIDS 2e

Oxford Handbook of Geriatric Medicine

Oxford Handbook of Infectious Diseases and Microbiology

Oxford Handbook of Key Clinical Evidence

Oxford Handbook of Medical Dermatology

Oxford Handbook of Medical Sciences 2e

Oxford Handbook of Medical Statistics

Oxford Handbook of Nephrology and Hypertension

Oxford Handbook of Neurology

Oxford Handbook of Nutrition and Dietetics 2e

Oxford Handbook of Obstetrics and Gynaecology 2e

Oxford Handbook of Occupational Health

Oxford Handbook of Oncology 3e

Oxford Handbook of Ophthalmology 2e

Oxford Handbook of Paediatrics

Oxford Handbook of Pain Management

Oxford Handbook of Palliative Care 2e

Oxford Handbook of Practical Drug Therapy 2e

Oxford Handbook of Pre-Hospital Care

Oxford Handbook of Psychiatry 2e

Oxford Handbook of Public Health Practice 2e

Oxford Handbook of Reproductive Medicine & Family Planning

Oxford Handbook of Respiratory Medicine 2e

Oxford Handbook of Rheumatology 2e

Oxford Handbook of Sport and Exercise Medicine

Oxford Handbook of Tropical Medicine 3e

Oxford Handbook of Urology 2e

Oxford Handbook of Medical Sciences

Second edition

Edited by

Dr Robert Wilkins

University Lecturer in Physiology,

University of Oxford;

American Fellow in Physiology,

St Edmund Hall, Oxford

Dr Simon Cross

Reader and Honorary Consultant,

Academic Unit of Pathology,

Department of Neuroscience,

School of Medicine, Dentistry & Health,

University of Sheffield, UK

Prof Ian Megson

Head, Department of Diabetes & Cardiovascular Science

University of the Highlands and Islands,

Inverness, UK

Dr David Meredith

Senior Lecturer in Biochemistry & Biomedical Science,

Oxford Brookes University,

Oxford, UK

Oxford Handbook of Medical Sciences - image 2

Oxford Handbook of Medical Sciences - image 3

Great Clarendon Street, Oxford OX2 6DP

Oxford University Press is a department of the University of Oxford.

It furthers the Universitys objective of excellence in research, scholarship,

and education by publishing worldwide in

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With offices in

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Oxford is a registered trade mark of Oxford University Press

in the UK and in certain other countries

Published in the United States

by Oxford University Press Inc., New York

Oxford University Press, 2011, except pp172181 section of

Chapter 2 ( Keith Frayn)

First edition published 2006

Reprinted 2008 (with corrections), 2009

Second edition published 2011

Reprinted 2013, 2015, 2016, 2017, 2018, 2019

The moral rights of the author have been asserted

Database right Oxford University Press (maker)

All rights reserved. No part of this publication may be reproduced,

stored in a retrieval system, or transmitted, in any form or by any means,

without the prior permission in writing of Oxford University Press,

or as expressly permitted by law, or under terms agreed with the appropriate

reprographics rights organization. Enquiries concerning reproduction

outside the scope of the above should be sent to the Rights Department,

Oxford University Press, at the address above

You must not circulate this book in any other binding or cover

and you must impose this same condition on any acquirer

British Library Cataloguing in Publication Data

Data available

Library of Congress Cataloging in Publication Data

Data available

Typeset by Glyph International, Bangalore, India

Printed in China

on acid-free paper by

C&C Offset Printing Co. Ltd

ISBN 9780199588442

10 9 8 6 5 4 3 2 1

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up-to-date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Preface to the first edition

This Handbook is written by Biomedical Scientists and Clinicians to disseminate the fundamental scientific principles that underpin clinical medicine. Frequent cross-referencing with the Oxford Handbook of Clinical Medicine helps to highlight the clinical relevance of specific issues. The challenge of this ambitious undertaking was to distil the contents of information found in several voluminous textbooks into a conveniently-sized handbook, without loss of important information. This has been achieved by sifting out the key facts that are crucial to understanding fundamental principles and presenting them as clear, brief statements or straightforward diagrams. The Handbook has been deliberately divided into sections that mirror modern medical teaching strategies; it builds from a clear, easily digestible account of basic cell physiology and biochemistry to an investigation of the traditional piers of medicine (anatomy, physiology, biochemistry, pathology, and pharmacology), intertwined in the context of each of the major systems relevant to the human body. Although primarily aimed at medical students, this Handbook will also provide a useful reference for science students studying any of the traditional biomedical sciences.

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