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Gideon M. Hirschfield (editor) - The Liver in Systemic Disease: A Clinicians Guide to Abnormal Liver Tests

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The Liver in Systemic Disease

A practical guide for non-hepatologists who encounter abnormal liver test results in patients

The Liver in Systemic Disease is an easy-to-use and authoritative guide for non-hepatologist health care professionals who need guidance on the management of patients with abnormal liver tests. The book provides definitive advice for when further investigation, or changes in management, are indicated.

With a practical focus throughout the text, the editors explore when and how to investigate and manage patients whose primary disease is non-hepatic, but whose liver tests are unexpectedly abnormal. The Liver in Systemic Disease provides substantial flow diagrams and advice on the process, together with updates on the liver diseases non-hepatologists are most likely to encounter.

Take-home primers included in the book shine a light on best practice and recommended procedures when dealing with abnormal liver test results. The book also provides:

  • A thorough introduction to evaluate the liver, including serum liver tests, liver imaging, and liver biopsy
  • Comprehensive discussions of practical issues in patients with liver abnormalities, including the diagnosis of drug induced liver injury, prescribing in patients with abnormal liver tests, and more
  • Practical discussions of the management of patients with unexplained abnormal liver tests in primary care
  • In-depth examinations of secondary care management of patients with unexplained abnormal liver tests, including intensive care, and the care of infectious and immunosuppressed patients

The Liver in Systemic Disease is an indispensable resource for non-hepatologist medical practitioners seeking to understand the implications of abnormal liver tests and who wish to know when further investigation or alteration of management is indicated.

Gideon M. Hirschfield (editor): author's other books


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Table of Contents List of Tables Chapter 1 Chapter 3 Chapter 5 Chapter - photo 1
Table of Contents
List of Tables
  1. Chapter 1
  2. Chapter 3
  3. Chapter 5
  4. Chapter 6
  5. Chapter 7
  6. Chapter 8
  7. Chapter 9
  8. Chapter 10
  9. Chapter 11
  10. Chapter 12
  11. Chapter 13
  12. Chapter 14
  13. Chapter 15
  14. Chapter 16
  15. Chapter 17
  16. Chapter 18
  17. Chapter 19
  18. Chapter 20
List of Illustrations
  1. Chapter 1
  2. Chapter 3
  3. Chapter 4
  4. Chapter 5
  5. Chapter 6
  6. Chapter 7
  7. Chapter 8
  8. Chapter 10
  9. Chapter 11
  10. Chapter 12
  11. Chapter 13
  12. Chapter 14
  13. Chapter 15
  14. Chapter 17
  15. Chapter 18
  16. Chapter 20
Guide
Pages
The Liver in Systemic Disease
A Clinicians Guide to Abnormal Liver Tests

Edited by

Gideon M. Hirschfield

University of Toronto

Canada

Paramjit Gill

University of Warwick

Coventry

UK

James Neuberger

University Hospital Birmingham

Birmingham

UK

This edition first published 2023 2023 John Wiley Sons Ltd All rights - photo 2

This edition first published 2023
2023 John Wiley & Sons Ltd

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Gideon M. Hirschfield, Paramjit Gill and James Neuberger to be identified as the authors of the editorial material in this work has been asserted in accordance with law.

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John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA
John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK

Editorial Office
9600 Garsington Road, Oxford, OX4 2DQ, UK

For details of our global editorial offices, customer services, and more information about Wiley products visit us at www.wiley.com.

Wiley also publishes its books in a variety of electronic formats and by printondemand. Some content that appears in standard print versions of this book may not be available in other formats.

Limit of Liability/Disclaimer of Warranty
The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis, or treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

Library of Congress CataloginginPublication Data
Names: Hirschfield, Gideon M., author. | Gill, Paramjit, author. | Neuberger, James, author.
Title: The liver in systemic disease : a clinicians guide to abnormal liver tests / Gideon M. Hirschfield, Paramjit Gill, James Neuberger.
Description: Hoboken, NJ : Wiley, 2023. | Includes bibliographical references and index.
Identifiers: LCCN 2022032482 (print) | LCCN 2022032483 (ebook) | ISBN 9781119802136 (hardback) | ISBN 9781119802167 (adobe pdf) | ISBN 9781119802174 (epub)
Subjects: MESH: Liver Function Tests | Liver Diseasesdiagnosis
Classification: LCC RC845 (print) | LCC RC845 (ebook) | NLM QY 140 | DDC 616.3/62dc23/eng/20220912
LC record available at https://lccn.loc.gov/2022032482
LC ebook record available at https://lccn.loc.gov/2022032483

Cover Design: Wiley
Cover Image: yodiyim/Adobe Stock Photos

List of Contributors

Guruprasad P. Aithal
Nottingham University Hospitals NHS Trust, Nottingham, UK
University of Nottingham, Nottingham UK

William Bernal
Institute of Liver Studies, Kings College Hospital, London, UK

Innocent K. Besigye
College of Health Sciences, Makerere University, Kampala, Uganda

Marco Carbone
University of MilanoBicocca, Monza, Italy
European Reference Network on
Hepatological Diseases, San Gerardo
Hospital, Monza, Italy

Sheital Chand
Institute of Liver Studies, Kings College Hospital, London, UK

Louise China
Royal Free London NHS Foundation Trust, London, UK

Stefano Ciardullo
Policlinico di Monza, Monza, Italy
Division of Endocrinology, Department of Medicine and Surgery, University of MilanoBicocca, Italy

Matthew Collins
McMaster University, Hamilton, Ontario, Canada
Liver Care Canada, Hamilton, Ontario, Canada

Laura Cristoferi
University of MilanoBicocca, Monza, Italy
European Reference Network on Hepatological Diseases, San Gerardo Hospital, Monza, Italy

Morven Cunningham
Toronto General Hospital, Toronto, Ontario, Canada

Paramjit Gill
University of Warwick, Coventry, UK

Navjyot K. Hansi
Addenbrookes Hospital, Cambridge, UK

Peter C. Hayes
Royal Infirmary of Edinburgh, Edinburgh, UK

Pietro Invernizzi
University of MilanoBicocca, Monza, Italy
European Reference Network on Hepatological Diseases, San Gerardo Hospital, Monza, Italy

Dinesh Jothimani
Dr. Rela Institute and Medical Centre, Chromepet, Chennai, India

Mai Kilany
Toronto General Hospital, Toronto, Ontario, Canada

Michael J. Krowka
Mayo Clinic, Rochester, MN, USA

Michael D. Leise
Mayo Clinic, Rochester, MN, USA

Will Lester
University Hospitals Birmingham, Birmingham, UK

Graham Lipkin
Queen Elizabeth Hospital, Birmingham, UK

Gerry MacQuillan

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