Angela L. Williams - Immune System Disorders Sourcebook: Health Reference Series

Immune System Disorders

SOURCEBOOK

FOURTH EDITION

Health Reference Series

Immune System Disorders

SOURCEBOOK

FOURTH EDITION

Basic Consumer Health Information about Disorders of the Immune System, Including Immune System Function and Response, Diagnosis of Immune Disorders, Information about Inherited Immune Disease, Acquired Immune Disease, and Autoimmune Diseases, Including Primary Immune Deficiency, Acquired Immunodeficiency Syndrome (AIDS), Lupus, Multiple Sclerosis, Type 1 Diabetes, Rheumatoid Arthritis, and Graves Disease

Along with Treatments, Tips for Coping with Immune Disorders, Glossaries, and a Directory of Additional Resources

Bibliographic Note

Because this page cannot legibly accommodate all the copyright notices, the Bibliographic Note portion of the Preface constitutes an extension of the copyright notice.

* * *

OMNIGRAPHICS

Angela L. Williams, Managing Editor

* * *

Copyright 2020 Omnigraphics

ISBN 978-0-7808-1727-2

E-ISBN 978-0-7808-1728-9

Library of Congress Cataloging-in-Publication Data

Names: Omnigraphics, Inc., issuing body.

Title: Immune system disorders sourcebook.

Description: Fourth edition. | Detroit, MI: Omnigraphics, [2019] | Series: Health reference series | Includes index. | Summary: Provides basic consumer health information about immune system function, diseases, treatments and management of related disorders. Includes index, glossary of related terms, and other resources -- Provided by publisher.

Identifiers: LCCN 2019025721 (print) | LCCN 2019025722 (ebook) | ISBN 9780780817272 (library binding) | ISBN 9780780817289 (ebook)

Subjects: LCSH: Immunologic diseases--Popular works.

Classification: LCC RC582.I4626 2019 (print) | LCC RC582 (ebook) | DDC 616.97--dc23

LC record available at https://lccn.loc.gov/2019025721

LC ebook record available at https://lccn.loc.gov/2019025722

Electronic or mechanical reproduction, including photography, recording, or any other information storage and retrieval system for the purpose of resale is strictly prohibited without permission in writing from the publisher.

The information in this publication was compiled from the sources cited and from other sources considered reliable. While every possible effort has been made to ensure reliability, the publisher will not assume liability for damages caused by inaccuracies in the data, and makes no warranty, express or implied, on the accuracy of the information contained herein.

This book is printed on acid-free paper meeting the ANSI Z39.48 Standard. The infinity symbol that appears above indicates that the paper in this book meets that standard.

Printed in the United States

Table of Contents

Preface

About This Book

The bodys immune system usually works efficiently to ward off disease, but things can go wrong. Sometimes dysfunctions result from inherited conditions. Sometimes they are caused when bacteria or viruses, such as the human immunodeficiency virus (HIV), slip past normal immune system defenses. Sometimes, for reasons poorly understood, the immune system begins to attack normal body cells. This can result in an autoimmune disease. The National Institutes of Health (NIH) estimates that up to 23.5 million Americans suffer from autoimmune disease and that the prevalence is rising.

Immune System Disorders Sourcebook, Fourth Edition provides information about immune system function and related disorders. Readers will learn about inherited, acquired, and autoimmune diseases, including primary immune deficiency, acquired immunodeficiency syndrome (AIDS), lupus, uveitis, multiple sclerosis, type 1 diabetes, rheumatoid arthritis, and Graves disease. Information about symptoms and treatments is included, along with tips for coping with an immune disorder, suggestions for caregivers, glossaries of terms and diseases, and a directory of additional resources.

How to Use This Book

This book is divided into parts and chapters. Parts focus on broad areas of interest. Chapters are devoted to single topics within a part.

describes how the immune system works and explains both immune response and tolerance. It summarizes the types of disorders that affect the immune system and describes factors that influence its function. Research initiatives to help better understand the immune system and learn how it can be manipulated to produce health benefits are also described.

acquired immune system diseases that are not present at birth but that are acquired later. These can result from exposure to HIV, the bodys response to a transplant, or the inability to tolerate a substance in the environment. Inherited immune deficiency diseases explains the symptoms, diagnosis, and treatment of diseases that result when genetic defects cause essential parts of the immune system to be missing or to malfunction. Inherited immune deficiency diseases include primary immune deficiency (PID), ataxia-telangiectasia, selective IgA deficiency, and severe combined immunodeficiency (SCID), which is more commonly known as bubble boy disease.

explains the symptoms, diagnosis, and treatment of diseases caused when immune cells mistake the bodys own cells as invaders and attack them. It covers about Addison disease, Behet disease, Inflammatory bowel disease (IBD), and Inflammatory myopathies.

describes immune system reactions to medical treatments. Topics include serum sickness, blood transfusion reaction, transplant rejection, and anaphylaxis.

provides information for people concerned about the diagnostic challenges involved in identifying immune disorders. Facts about the tests most commonly used, including blood, gene, and allergy tests, are provided.

contains information about drug and gene therapies, plasmapheresis, and stem cell transplantation. Treatments used for specific immune diseases are also described.

provides tips for individuals and families living with an autoimmune or immune system disease, immunization recommendations, and suggestions for students and travelers with immune system disorders.

offers glossaries of immune system terms and autoimmune diseases and a directory of resources.

Bibliographic Note

This volume contains documents and excerpts from publications issued by the following U.S. government agencies: Centers for Disease Control and Prevention (CDC); Clinical Center (CC); Federal Bureau of Prisons (BOP); Genetic and Rare Diseases Information Center (GARD); Genetics Home Reference (GHR); National Cancer Institute (NCI); National Eye Institute (NEI); National Heart, Lung, and Blood Institute (NHLBI); National Human Genome Research Institute (NHGRI); National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institute of Environmental Health Sciences (NIEHS); National Institute of General Medical Sciences (NIGMS); National Institute of Mental Health (NIMH); National Institute of Neurological Disorders and Stroke (NINDS); National Institutes of Health (NIH); Office on Womens Health (OWH); U.S. Department of Health and Human Services (HHS); and U.S. Food and Drug Administration (FDA).