For their contributions on various technical matters, I would like to thank the following people: James Stellar, Roy Freeman, Alice Janjigian, Karen Chase, Alice Gervasini, Tweedy Watkins, Deborah Copeland, Jack Reynolds, Karen Hutchinson, Karen Zoeller, Michael Ku, Richard Deth, Marjorie Dalba, Amy Sbordone, Peter Mollo, Michael Carvalho, Kate Flora, Kenneth Cohen, Charles ONeill, and Malcolm Childers.
A special thanks to Dr. Daniel Press for his generous time and great help with medical matters. Also to Barbara Shapiro for her great advice and encouragement.
A very special thanks to my own special muse, Wanda Hunt, for her extraordinary assistance, her patience at the tape recorder, and her inspiration.
And, of course, my deep gratitude to my agent, Susan Crawford, my editor, Natalia Aponte, and my publisher, Tom Doherty, for their continuing support.
Im also indebted to the books Alzheimer Solutions: A Personal Guide for Caregivers by Jim Knittweis and Judith Harch and The Story of My Father by Sue Miller.
Homers Island Seven Weeks Later
A SMALL SIGN ON THE beach read BEWARE OF JELLYFISH!
Nice timing, Jack said, and handed Ren a plate.
They sat on beach chairs by the waters edge picnicking on shish kebab, stuffed grape leaves, pilaf, and stewed vegetables.
In the late sixties, she was on a marine science panel in Cambridge with Jacques Cousteausomething about the threat of industrial pollution and global warming on the oceans of the world. Thaddeus Sherman was impressed, and they started talking. One thing led to the next, and he invited her to stay here because it was the only place in the northeast where Caribbean sea life shows up. One visit, and she fell in love with the place and started collecting specimens.
Jack poured two glasses of chardonnay.
Sounds like she was a very special woman.
I think she was. They clicked glasses.
Today was the thirty-first anniversary of Rose Sarkisians death.
She apparently had an affair with Gavin Moy, who was more her typeacademically speakingthan the man she married. Who knows? Records say they were in divorce proceedings before he was killed in a plane crash. They hid that fact on the gravestone to save face.
Jack also learned that Rose had specialized in the therapeutic properties of marine toxins. After having bagged some Solakandjis, she had chemical assays done on the toxin and found that the compound demonstrated beneficial properties on the neurological system. When Moy decided to start researching these neurological properties, Rose went to work with him as a partner. They apparently became lovers. And when she became pregnant with Jack, she insisted that he either marry her or provide financially for Jacks upbringing. Moy refused. They fought, and she was killed. Moy and his people went on to develop an FDA application of the compound for thetreatment of dementia. But Rose Sarkisian was the prime mover. She had identified the agent and its therapeutic properties with lab mice.
Mookie. Wheres Mookie?
And that stuffed animal was what she had made for her little boy.
Jack looked out over the water to Skull Rock and the glittering azure expanse beyond. And for a moment he thought he heard thunder.
I didnt know that Nick knew your mother. He never said anything.
Except he must have suspected when he saw me on his MRI patient list. Then he did some name and date checks.
He must have suspected foul play all along, since she had identified the toxins benefits, then mysteriously disappeared.
My guess. And then Moy appropriated the discovery and slapped his name on the patents.
Which is why Nick kept pressing to discover whether you remembered anything.
He even sent you after me. Kind of glad he did.
She smiled. Me, too. He felt a flush of warmth as she took his hand.
Because there was no statute of limitations in Massachusetts, Gavin Moy had been indicted for murder, the evidence being his own confession on tape. Likewise, Jordan Carr and Teddy Moy were also indicted for the murder of Nick Mavros. After the discovery of Nicks body, the film in his camera had been developed. At first it had meant nothing in the investigation of the accident. But when the police heard the tape of the exchange recorded in Moys office, they went back to the film to discover on the last frame a face staring out from a clutch of dark bushes. When blown up, the face in the dark looking directly at the camera was Jordan Carrs.
But that was not the only evidence for the prosecution undercutting Carrs insistence that he had not been at Bryce Canyon. Teddy Moy had decided not to go down alone. He confessed that Jordan had been complicit with him and Gavin Moy, although Teddy had done the actual dirty work of pushing Nick off the cliff. There was suspicion that Teddy was also responsible for Peter Habibs death, now being investigated as a possible homicide.
Hows Louis doing?
Fine. I was out to their place the other day. He sends his regards.
He was a real hero.
Yes. He really was. No, is.
As Ren had explained it, that night at Moys estate Louis had apparentlyexperienced a memory-induced hallucination, believing he was engaged in a long-anticipated assault on North Korean military high command including individuals who had participated in the torture and execution of members of his platoon. And although he had experienced no more such hallucinations since, he could not be taken off the drug, of course. But he was being more closely monitored and treated with different doses of medications that would block his flashbacks and possible hallucinations without sending him into a stupor. His short-term memory continued to improve, and he was living almost a normal life again.
But understanding why some patients like Louis Martinetti were susceptible to flashbacks clearly required more research. The problem was that after four to six months of regular dosing, sixty percent of the patients showed cognitive and functional improvement; yet, for some reason, nearly half of those experienced disturbing flashbacks. As a result, the Memorines FDA application was withdrawn. Those trial patients already on the compound would be continued and closely monitored and properly treated for flashback seizures. Meanwhile, the FDA had mandated that GEM Tech scientists in conjunction with outside research groups make aggressive efforts to determine what genetic, chemical, or demographic factors might account for the phenomena before reapplication of Memorine or any refashioned compound for approval.
Understandably, thousands of AD patients, caregivers, and health-care workers were disappointed at the news. But Orman-Witt, the director of the FDA, said that this was medical progress. This initiative is going to push drug companies to be more thoughtful when testing their products and not rush them to market or cover up damaging evidence. The hope was for a safe and efficacious treatment within two years.
Alas, the world would have to wait. And when some safe variation of Memorine eventually reached the market, Rose Sarkisian would share credit for its discovery.
Jacks own flashbacks and related nightmares had also faded, as if on some deep level a ghost had been laid to rest. He was back at the gym with Vince and pumping chrome once again. And next month hed be back in the classroom at Carleton Prep and helping Vince out hosting Yesterdays on weekends.