Frederick Southwick - Infectious Diseases A Clinical Short Course 3/E

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Medicine is an ever-changing science. As new research and clinical experience broaden our Despite dire warnings that we are approaching the end of the antibiotic era, the incidence of antibiotic-resistant bacteria continues to rise. The proportions of penicillin-resistant Streptococcus pneumoniae, hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus (VRE) strains continue to increase. Community-acquired MRSA (cMRSA) is now common throughout the world. Multiresistant Acinetobacter and Pseudomonas are everyday realities in many of our hospitals. The press is now warning the lay public of the existence of dirty hospitals. As never before, it is critical that health care providers understand the principles of proper anti-infective therapy and use anti-infective agents judiciously. These agents need to be reserved for treatable infectionsnot used to calm the patient or the patients family. Too often, patients with viral infections that do not warrant anti-infective therapy arrive at the physicians office expecting to be treated with an antibiotic. And health care workers too often prescribe antibiotics to fulfill those expectations. Physicians unschooled in the principles of microbiology utilize anti-infective agents just as they would more conventional medications, such as anti-inflammatory agents, anti-hypertensive medications, and cardiac drugs. They use one or two broad-spectrum antibiotics to treat all patients with.

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To my parents, Ann and Wayne Southwick, and children Ashley, Peter, Robyn, and Karli. And finally to my beautiful wife Kathie Southwick for her loving encouragement and continual support.

Bernard Hirschel, M.D.

Professor of Medicine

Division of Infectious Diseases

University of Geneva

Geneva, Switzerland

P. Daniel Lew, M.D.

Professor of Medicine, and Chief of Infectious Diseases and Chairman of Medicine Subspecialties

University of Geneva

Geneva, Switzerland

Frederick S. Southwick, M.D.

Professor of Medicine

Division of Infectious Diseases

University of Florida College of Medicine

Gainesville, Florida

Sankar Swaminathan, M.D.

Don Merrill Rees Presidential Endowed Chair

Professor of Medicine

Chief of Infectious Diseases

University of Utah School of Medicine

Salt Lake City, Utah

The challenges of infectious diseases are daunting. As our world shrinks, person-to-person spread of influenza and coronavirus has the potential to cause pandemics. The overuse of antibiotics continues to increase the prevalence of highly resistance bacteria. Increasing numbers of patients receive prosthetic devices that subsequently become infected. New immunosuppressive treatments of patients with connective tissue diseases and inflammatory bowel disease increase the risk of opportunistic infections. HIV remains with us and thanks to multiple antiretroviral medications, these patients are experiencing nearly normal life spans increasing the number of HIV-infected patients requiring continued care.

How do medical students, physician assistants, nurse practitioners, and physicians learn this important subspecialty? The textbooks on infectious diseases are generally over 1000 pages in length. However, the average clinician does not have time to read these books in their entirety. There are Internet products that offer detailed descriptions of each individual infectious disease. However, these products offer a fragmented approach that makes a full understanding of the field difficult. Infectious Diseases: A Clinical Short Course concisely covers the key areas of infectious diseases and is designed to be read in 30 days, the usual duration of a clinical elective. At the beginning of each chapter, the estimated time required to read each chapter is included to allow readers to budget their time. To stimulate the readers attention, each chapter begins with a series of guiding questions. These questions are followed by an estimate of the potential severity of each disease to provide the less experienced clinician with a sense of how quickly he or she should be initiating treatment. Actual clinical cases are included for every major disease to link the facts to real patients. Key points are summarized in text boxes to reinforce the most important facts, and allow the reader to quickly review each topic. This tool is particularly effective for reviewing board examinations.