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Charis Thompson - Good Science: The Ethical Choreography of Stem Cell Research

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Charis Thompson Good Science: The Ethical Choreography of Stem Cell Research
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After a decade and a half, human pluripotent stem cell research has been normalized. There may be no consensus on the status of the embryo -- only a tacit agreement to disagree -- but the debate now takes place in a context in which human stem cell research and related technologies already exist. In this book, Charis Thompson investigates the evolution of the controversy over human pluripotent stem cell research in the United States and proposes a new ethical approach for good science. Thompson traces political, ethical, and scientific developments that came together in what she characterizes as a procurial framing of innovation, based on concern with procurement of pluripotent cells and cell lines, a pro-cures mandate, and a proliferation of bio-curatorial practices. Thompson describes what she calls the ethical choreography that allowed research to go on as the controversy continued. The intense ethical attention led to some important discoveries as scientists attempted to invent around ethical roadblocks. Some ethical concerns were highly legible; but others were hard to raise in the dominant procurial framing that allowed government funding for the practice of stem cell research to proceed despite controversy. Thompson broadens the debate to include such related topics as animal and human research subjecthood and altruism. Looking at fifteen years of stem cell debate and discoveries, Thompson argues that good science and good ethics are mutually reinforcing, rather than antithetical, in contemporary biomedicine.

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Good Science

Inside Technology

edited by Wiebe E. Bijker, W. Bernard Carlson, and Trevor Pinch

Janet Abbate, Inventing the Internet

Atsushi Akera, Calculating a Natural World: Scientists, Engineers and Computers during the Rise of U.S. Cold War Research

Morana Ala, Handling Digital Brains: A Laboratory Study of Multimodal Semiotic Interaction in the Age of Computers

Stathis Arapostathis and Graeme Gooday, Patently Contestable: Electrical Technologies and Inventor Identities on Trial in Britain

Charles Bazerman, The Languages of Edisons Light

Marc Berg, Rationalizing Medical Work: Decision-Support Techniques and Medical Practices

Wiebe E. Bijker, Of Bicycles, Bakelites, and Bulbs: Toward a Theory of Sociotechnical Change

Wiebe E. Bijker and John Law, editors, Shaping Technology/Building Society: Studies in Sociotechnical Change

Wiebe E. Bijker, Roland Bal, and Ruud Hendricks, The Paradox of Scientific Authority: The Role of Scientific Advice in Democracies

Karin Bijsterveld, Mechanical Sound: Technology, Culture, and Public Problems of Noise in the Twentieth Century

Stuart S. Blume, Insight and Industry: On the Dynamics of Technological Change in Medicine

Pablo J. Boczkowski, Digitizing the News: Innovation in Online Newspapers

Geoffrey C. Bowker, Memory Practices in the Sciences

Geoffrey C. Bowker, Science on the Run: Information Management and Industrial Geophysics at Schlumberger, 19201940

Geoffrey C. Bowker and Susan Leigh Star, Sorting Things Out: Classification and Its Consequences

Louis L. Bucciarelli, Designing Engineers

Michel Callon, Pierre Lascoumes, and Yannick Barthe, Acting in an Uncertain World: An Essay on Technical Democracy

H. M. Collins, Artificial Experts: Social Knowledge and Intelligent Machines

Park Doing, Velvet Revolution at the Synchrotron: Biology, Physics, and Change in Science

Paul N. Edwards, The Closed World: Computers and the Politics of Discourse in Cold War America

Andrew Feenberg, Between Reason and Experience: Essays in Technology and Modernity

Tarleton Gillespie, Pablo J. Boczkowski, and Kirsten A. Foot, editors, Media Technologies: Paths Forward for Social Research

Michael E. Gorman, editor, Trading Zones and Interactional Expertise: Creating New Kinds of Collaboration

Herbert Gottweis, Governing Molecules: The Discursive Politics of Genetic Engineering in Europe and the United States

Joshua M. Greenberg, From Betamax to Blockbuster: Video Stores and the Invention of Movies on Video

Kristen Haring, Ham Radios Technical Culture

Gabrielle Hecht, Entangled Geographies: Empire and Technopolitics in the Global Cold War

Gabrielle Hecht, The Radiance of France: Nuclear Power and National Identity after World War II

Kathryn Henderson, On Line and On Paper: Visual Representations, Visual Culture, and Computer Graphics in Design Engineering

Christopher R. Henke, Cultivating Science, Harvesting Power: Science and Industrial Agriculture in California

Christine Hine, Systematics as Cyberscience: Computers, Change, and Continuity in Science

Anique Hommels, Unbuilding Cities: Obduracy in Urban Sociotechnical Change

Deborah G. Johnson and Jameson W. Wetmore, editors, Technology and Society: Building Our Sociotechnical Future

David Kaiser, editor, Pedagogy and the Practice of Science: Historical and Contemporary Perspectives

Peter Keating and Alberto Cambrosio, Biomedical Platforms: Reproducing the Normal and the Pathological in Late-Twentieth-Century Medicine

Eda Kranakis, Constructing a Bridge: An Exploration of Engineering Culture, Design, and Research in Nineteenth-Century France and America

Jens Lachmund, Greening Berlin: The Co-Production of Science, Politics, and Urban Nature

Christophe Lcuyer, Making Silicon Valley: Innovation and the Growth of High Tech, 19301970

Pamela E. Mack, Viewing the Earth: The Social Construction of the Landsat Satellite System

Donald MacKenzie, Inventing Accuracy: A Historical Sociology of Nuclear Missile Guidance

Donald MacKenzie, Knowing Machines: Essays on Technical Change

Donald MacKenzie, Mechanizing Proof: Computing, Risk, and Trust

Donald MacKenzie, An Engine, Not a Camera: How Financial Models Shape Markets

Cyrus C. M. Mody, Instrumental Community: Probe Microscopy and the Path to Nanotechnology

Maggie Mort, Building the Trident Network: A Study of the Enrollment of People, Knowledge, and Machines

Peter D. Norton, Fighting Traffic: The Dawn of the Motor Age in the American City

Helga Nowotny, Insatiable Curiosity: Innovation in a Fragile Future

Ruth Oldenziel and Karin Zachmann, editors, Cold War Kitchen: Americanization, Technology, and European Users

Nelly Oudshoorn and Trevor Pinch, editors, How Users Matter: The Co-Construction of Users and Technology

Shobita Parthasarathy, Building Genetic Medicine: Breast Cancer, Technology, and the Comparative Politics of Health Care

Trevor Pinch and Richard Swedberg, editors, Living in a Material World: Economic Sociology Meets Science and Technology Studies

Paul Rosen, Framing Production: Technology, Culture, and Change in the British Bicycle Industry

Richard Rottenburg, Far-Fetched Facts: A Parable of Development Aid

Susanne K. Schmidt and Raymund Werle, Coordinating Technology: Studies in the International Standardization of Telecommunications

Wesley Shrum, Joel Genuth, and Ivan Chompalov, Structures of Scientific Collaboration

Rebecca Slayton, Arguments that Count: Physics, Computing, and Missile Defense, 19492011

Chikako Takeshita, The Global Politics of the IUD: How Science Constructs Contraceptive Users and Womens Bodies

Charis Thompson, Good Science: The Ethical Choreography of Stem Cell Research

Charis Thompson, Making Parents: The Ontological Choreography of Reproductive Technology

Dominique Vinck, editor, Everyday Engineering: An Ethnography of Design and Innovation

Good Science

The Ethical Choreography of Stem Cell Research

Charis Thompson

The MIT Press
Cambridge, Massachusetts
London, England

2013 Massachusetts Institute of Technology

All rights reserved. No part of this book may be reproduced in any form by any electronic or mechanical means (including photocopying, recording, or information storage and retrieval) without permission in writing from the publisher.

Library of Congress Cataloging-in-Publication Data

Thompson, Charis.

Good science : the ethical choreography of stem cell research / Charis Thompson, Inside Technology.

p. cm.

Includes bibliographical references and index.

ISBN 978-0-262-02699-4 (hardcover : alk. paper)

ISBN 978-0-262-31904-1 (retail e-book)

1. Stem cellsResearchMoral and ethical aspectsUnited States. 2. Stem cellsResearchGovernment policyCalifornia. 3. Stem cellsResearchUnited StatesFinance. 4. Federal aid to medical researchUnited States. I. Title.

QH588.S83.T48 2013

[R853.H8]

616.02774dc23

2013024261

d_r1

Acknowledgments

I thank family, friends, colleagues, and students for their inspiring intellectual work and for their commitment to the issues of the day. I am especially fortunate to have worked with the faculty, staff, and students of the units that together make up the Gender and Womens Studies Department, the Center for Science, Technology, and Medicine in Society, and the Center for Race and Gender at UC Berkeley. I am grateful to the Deans of the Social Sciences and Humanities, the Committee on Research at UC Berkeley, and the Mellon Foundation for supporting the research upon which this book is based. I also much appreciate the support from the California Institute for Regenerative Medicine and from UC Berkeleys former Chancellor, Robert Birgeneau, and Executive Vice Chancellor, George Breslauer, for the Stem Cells and Society program.

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