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William B. Miller Jr. - Bioverse: How the Cellular World Contains the Secrets to Lifes Biggest Questions

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By exploring the extent of our deeply integrated cellular world, Bioverse provides profound insights about ourselves, our health and well-being, our social systems, and our permanent relationship to the planet and the cosmos.For as long as humans have been on Earth, we have looked up to the stars for clues to our own existence. Medical doctor and evolutionary biologist William B. Miller, Jr. suggests that we may find more meaningful solutions at the end of a microscope rather than a telescope. Using powerful analogies and exacting science, Bioverse explores the wonders of the perpetual partnership between our personal cells and the microbial world, resulting in an entirely new view of our living planet. To understand life in all its varieties, we must undertake to understand our cells. While the partnership between our cells and our microbes has largely been thought of as that of host and guest, Miller reveals the true partnership under which both our microbial fraction and our own personal cells conduct a life-long dialogue, redefining our traditional conceptions of intelligence and problem-solving. This radical new approach explains exactly how our human choices are centered within the same cellular rules that enable our cells to seamlessly sustain our lives. We are now entering the Era of the Cell, a time in history during which medical and scientific innovations have spurred growth far beyond ever imagined by our ancestors. For the first time, we are not only building machines to enhance our lives but engineering living organisms to assist our futures. From the biological origins of evolution to the invention of the compound microscope by a Dutch lens maker in the 17th century, to new research that reveals surprising links between our microbiome and our moods and behavior, and surprising stories of the cellular world from the deepest oceans, wildest jungles, and outer reaches of our solar system, Miller introduces readers to a greater understanding of our impact on the planet and the worlds reciprocal impact on each of us. By exploring the extent of our deeply integrated cellular world, Bioverse provides profound insights about ourselves, our health and well-being, our social systems, and our permanent relationship to the planet and the cosmos.

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A Note on Medicine and Health

The material contained in this book is for informational purposes only. None of this material is intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking any new health care regimen.

This book is an ample illustration of its primary message emphasizing the universality of connectedness. When rightly considered, everyone I have met and interacted with throughout my life merits recognition; however, a few have had such predominant influence that they deserve special mention. This book would not exist absent an invitation to frame its ideas from two exceptional entrepreneurs, Ara Katz and Raja Dhir. My deepest thanks to both. I was also fortunate to be represented by my extraordinary agent, Wendy Keller. Her critical analysis of the book, keen appraisal of its prospects, and inspiring and definitive guidance was crucial to its success. Without it, I would never have had the corresponding opportunity to interact with Jake Bonar, my talented editor at Rowman and Littlefield, and my meticulous copyeditor, Veronica Jurgena. Their deft touch is everywhere throughout the book. Finally, it is appropriate to honor the scientific community that has provided the continuous advances that undergird the principles of Bioverse. Many of my brilliant colleagues claim special thanks, John Torday, Frantiek Baluka, Arthur Reber, Michael Levin, Frank Ryan, Denis Noble, Brian J. Ford, Perry Marshall, Jon Lieff, Tam Hunt, Francisco Enguita, and Richard Jacobs. All have contributed mightily to my thoughts, and their insights are central to this book.

She lay on her back, breathing softly, and wondered at the limitless night sky. Everywhere above, the measureless stars were glittering specks of incandescent light. Across trillions of miles and billions of years, their testament now reached her. In their scant shimmering glow, they upheld a silent message. You are united with us through invisible threads, not just in this moment but for eternity.

There is no doubt that humans have unique gifts. We are well aware of them and assume that an innate superiority categorically separates us from the rest of our planetary companions. Few question our natural supremacy over all other living things. Yet, despite that lofty self-regard, our own lives are plagued with uncomfortable uncertainties and personal doubts. There are so many nagging questions that rattle our thoughts. We often question ourselves: Why do I make bad choices? Why am I always unhappy? Those who are lonely may ask in despair, Do I matter at all? Does anyone care? Each of these anxieties shares a common denominatorthey reflect our continuous struggle to find our place in an unsettling world. Part of the dilemma is a continuous assault by a barrage of self-aggrandizing social media that is invariably unsettling. It provokes us. We stress about our family, friends, and society at large. For some, the status of the entire planet is woeful. For others, the entire universe seems scrambled. Whether we admit our misgivings or not, we are all united in a forced confrontation with agitating inner questions. You know the ones that Im talking about. Theyre the disconcerting ones that spring out of nowhere during the day or visit uninvited in the middle of the night.

What difference do I make?

How should I be living my life so that it makes some sense?

Feeling adrift is a nearly universal sensibility in this tumultuous moment. Our prior societal touchstones have lost their force. Many believe that they are simply wandering through life, hoping to find some security and purpose along the way. Many silently wonder, Am I simply running out the clock with my life?

Throughout history, religious faith has provided answers to these vexing doubts. Yet, for many in our era, the piety that provided comfort for millennia no longer seems legitimate. As a result, our daily anxieties grind. There appears to be no comforting refuge. Most would agree that we live in an angst-ridden age. In reaction, many compensate through a relentless search for personal fulfillment. For some, it is a devotion to causes. Others seek some general spiritual reassurance in the hope of divining some identifiable purpose to their lives.

Fortunately, there is an antidote for this modern malady of prevalent unease. In this fretful time, science can provide evidence that there is genuine permanent meaning in your life. Exacting science provides direct assurance that our lives are much more than just in the moment. This heartening conclusion springs from an unforeseen source. An ongoing exploration of the intricate wonders of our cells has unexpectedly revealed previously hidden connections between ourselves, our planet, and the cosmos.

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