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Eric Topol - Deep Medicine

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One of Americas top doctors reveals how AI will empower physicians and revolutionize patient care

Medicine has become inhuman, to disastrous effect. The doctor-patient relationshipthe heart of medicineis broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard.

Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine...

Eric Topol: author's other books


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Copyright 2019 by Eric Topol Cover design by Ann Kirchner Cover image copyright - photo 1

Copyright 2019 by Eric Topol

Cover design by Ann Kirchner

Cover image copyright KDYA979/shutterstock.com

Cover copyright 2019 Hachette Book Group, Inc.

Hachette Book Group supports the right to free expression and the value of copyright. The purpose of copyright is to encourage writers and artists to produce the creative works that enrich our culture.

The scanning, uploading, and distribution of this book without permission is a theft of the authors intellectual property. If you would like permission to use material from the book (other than for review purposes), please contact permissions@hbgusa.com. Thank you for your support of the authors rights.

Basic Books

Hachette Book Group

1290 Avenue of the Americas, New York, NY 10104

www.basicbooks.com

First Edition: March 2019

Published by Basic Books, an imprint of Perseus Books, LLC, a subsidiary of Hachette Book Group, Inc. The Basic Books name and logo is a trademark of the Hachette Book Group.

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The publisher is not responsible for websites (or their content) that are not owned by the publisher.

The Library of Congress has cataloged the hardcover edition as follows:

Names: Topol, Eric J., 1954author.

Title: Deep medicine : how artificial intelligence can make healthcare human again / Eric Topol.

Description: First edition. | New York : Basic Books, March 2019. | Includes bibliographical references and index.

Identifiers: LCCN 2018043186 (print) | LCCN 2018043932 (ebook) | ISBN 9781541644649 (ebook) | ISBN 9781541644632 (hardcover)

Subjects: | MESH: Artificial Intelligence | Medical Informatics | Diagnosis, Computer-Assisted | Therapy, Computer-Assisted | Quality Improvement

Classification: LCC R858 (ebook) | LCC R858 (print) | NLM W 26.55.A7 | DDC 362.10285dc23

LC record available at https://lccn.loc.gov/2018043186

ISBNs: 978-1-5416-4463-2 (hardcover); 978-1-5416-4464-9 (ebook)

E3-20190205-JV-NF-ORI

The Patient Will See You Now

The Creative Destruction of Medicine

To my familySusan, Sarah, Evan, Antonio, Julian, and Isabellawho provided unconditional support and the deep inspiration for me to pursue this work

Life can only be understood backwards; but it must be lived forwards.

S REN K IERKEGAARD

A MONG THE MANY CHARACTERISTICS THAT MAKE US HUMAN and that distinguish us from other animals must be our urge to look back. It is hard to imagine that other species brood late at night about the one that got away or a job they could have had. But we also do it as a form of scholarship, looking back at ourselves as a species, as if we were the Creator, poring through recorded history, charting the milestones of progress, from the harnessing of fire to the microchip. Then we try to make sense of it.

Kierkegaards thesis that we live life forward but understand it backward might mean nothing more than we remember the past, and at best we have an (inaccurate) record of it. But with apologies to him and to George Santayana, understanding history does not provide immunity to repeating it. A cursory scan of the news shows this to be true. In short, even as a guide to what to avoid, the past is unreliable. Only the future is certain because it is still ours to make.

Which brings us to futurists, like the author of this wonderful book. Such individuals, on hearing that the Wright brothers became airborne, can foresee budget airlines, airline hubs, and humans walking on the moon. These historians of the now begin with the study of what is today, asking not how to avoid the perils of the past but how to maximize the advantages of the future. Pencil and paper, or tablet, in hand, they patrol the frontiers of science and tech and interview those at the cutting edge, including those who have tumbled over. They seek out innovators, scientists, mavericks, and dreamers. They listen, they monitor, they filter, and they synthesize knowledge across many disciplines to make sense of it all for the rest of us. As Deep Medicine will show you, theirs is a formidable intellectual task and an extraordinarily creative one. It involves as much right brain as left, and it invokes the muses, because what is in this book is as much inspiration as it is exposition.

Deep Medicine is Eric Topols third exploration of what will be. The previous books, examined in the light of where we are now, reveal his prescient vision. In Deep Medicine, Eric tells us we are living in the Fourth Industrial Age, a revolution so profound that it may not be enough to compare it to the invention of steam power, the railroads, electricity, mass production, or even the computer age in the magnitude of change it will bring. This Fourth Industrial Age, revolving around artificial intelligence (AI), robotics, and Big Data, heralds a profound revolution that is already visible in the way we live and work, perhaps even in the way we think of ourselves as humans. It has great potential to help, but also to harm, to exaggerate the profound gap that already exists between those who have much and those who have less each passing year.

This revolution will overtake every human endeavor, medicine not least among them. Medicine itself is at a moment of crisis. As a profession, for all the extraordinary advances in the art and science of medicine in the last four decades, we have too often failed our patients. We fail to follow proven guidelines, and we fail in the art by not seeing the unique person in front of us. We know their genome, but by not listening to their story, we dont register their broken heart. We fail to see the neurofibroma that are raising lumps all over their skin, a finding that is relevant to their paroxysmal hypertension but that does need the gown to come off during the exam, does need our attention to be on the body and not on the screen; we miss the incarcerated hernia that explains an elderly patients vomiting and have to wait for an expensive CAT scan and a radiologist to tell us what was before our eyes. Countries with the biggest expenditures on healthcare lag behind those that spend much less in basic rankings such as infant mortality. I think it is very telling that Deep Medicine opens with a profound, personal, revealing anecdote of the authors own painful and harrowing medical encounter that was a result of not being seen as an individual, someone with an uncommon disorder.

It should not surprise us that technology, despite the dramatic way it has altered our ability to image the body, to measure and monitor its molecular structure, can also fail just as badly as humans fail. The glaring example is in the electronic healthcare record systems (EHRs) currently in use in most hospitals. These EHRs were designed for billing, not for ease of use by physicians and nurses. They have affected physician well-being and are responsible for burnout and attrition; moreover, they have forced an inattentiveness to the patient by virtue of an intruder in the room: the screen that detracts from the person before us. In Intoxicated by My Illness, a poignant memoir about a mans ultimately fatal prostate cancer, Anatole Broyard articulates a wish that his urologist would brood on my situation for perhaps five minutes, that he would give me his whole mind just once, be bonded with me for a brief space, survey my soul as well as my flesh, to get at my illness,

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