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Table of Contents

CHAPTER 1: Understanding Cancer

Cancer is such a common disease nowadays that one would expect people to be comfortable discussing this each other. However, merely mentioning the word Cancer makes people scared and uncomfortable, and after an awkward silence, the discussion moves on to some other topic.
This is due to the fact that cancer is still quite less understood, and we all are scared of discussing something that is so widespread, cruel and unpredictable.
However, this need not be the case, and the more we understand cancer deeply, the more we will be able to devise strategies to avoid, and if needed, treat cancer.

Cancer can be scary due to its myriad forms. However, a deeper understanding of cancer can help us overcome it.

What is Cancer?

Cancer is a group of diseases involving abnormal cell growth with the potential to kill the patient. Unlike benign tumours, cancer cells have the ability to spread to other parts of the body.
Interestingly, at any given point of time, millions of cancer cells are present even in a healthy body. These cells are always fighting the defensive mechanism of the body and losing the battle. If cancer were so bad, why would a healthy body have so many cancer cells all the time, and spend energy fighting them? While there is no conclusive evidence, it seems that this is body's mechanism to keep itself battle ready for a possible real invasion when it happens.
This is good news as this indicates that our body inherently knows about cancer and has adapted accordingly by keeping itself prepared for any attack.

Our body already knows how to defeat cancer cells

This also means that the collective knowledge of modern medicine about cancer is at best limited, and traditional ways of societies that have preserved their way of living can hold cues about keeping cancer at bay. We will study about one such society later in the book.

Inside the mind of a Cancer cell

To understand if cancer is a friend, foe or a friend turned foe, it is important to gain a deeper understanding of how a cancer cell 'thinks'. It may appear odd to treat a cancer cell as an intelligent being, but a study of its behaviour as it transforms from a normal cell to a precancerous cell to a fast multiplying cancerous cell looks remarkably similar to how a long-oppressed society would behave in response to a high handedness of its occupiers.
Hence, let us look at a cell's journey from a normal to a full blown (metastasized) cancerous cell.

Types of Cancer cells

Normal or Healthy Cells: In its normal state, the human body works harmoniously with an intricate mechanism of feedback loop ensuring the body maintains a fine balance. For example, if a person is running hard, the muscle cells that need the most oxygen send a signal to the brain asking for more oxygen, which in turn instructs the lungs and heart to work harder. This happens without the conscious involvement of the person.

However, if the person continues to run fast even if the lungs and heart cannot keep up, the muscle cells get starved of oxygen, and the person feels too tired to keep running. This prevents death by exhaustion.

A Healthy Cell is Happy with its surroundings

Precancerous Cells : Imagine however that this harmony is broken and cells which are under stress do not get the right kind of response from the body-mind combination. Let us take the example of a person who is smoking a cigarette for the first time. In this case, the person's lung cells will start receiving nicotine and soot filled smoke, and these cells will send a strong signal to the brain asking the body to stop smoking. This often manifests itself as a strong and immediate cough, and the taste buds also do their bit by making the taste appear awful in the beginning.

Lungs getting irritated due to smoke

If the person continues to smoke in spite of the strong initial feedback, the cells start sending even stronger messages to the brain, akin to the SOS messages that a sinking ship would send, or strong protests by an oppressed society.

If the situation continues for a long time, these messages become so strong that these can be detected by cancer screening tests as changes in the cell structure, and such oppressed cells are known as Precancerous cells.

It is important to note that most of the precancerous cells do not become cancerous, and they can revert to being normal cells if the feedback mechanism starts to work and the body/mind combination takes appropriate action. This would be akin to the protesting society going back to their normal day to day life if the government starts to provide a just society and agrees to some of their demands.

A precancerous cell showing its anger

Cancerous Cells: If the feedback mechanism does not work as expected however, and the cells have had enough of the oppressive environment, they go on a full-scale offensive against the body.

These cells start preparing for a rebellion by multiplying much faster, with each multiplication taking place at a much younger age without waiting for the cell to attain full maturity. As a result, these cells cannot do anything productive for the body, and their sole purpose is to crowd out the normal cells so that the organ that they are a part of starts to malfunction.

This scenario, though at a microscopic level, is very similar to a society that has rebelled against a state and is raising children and young soldiers to fight a war to the finish.

Since these cells do not mature, they all look very similar, and are known as 'Undifferentiated Cells' in medical terminology. The more the cells are Undifferentiated, the more the cancer is said to be invasive.

It is important that the cancer is detected and treated early at this stage as otherwise the cancer, which is still localized (in situ in medical parlance) can spread to other parts of the body, a state known as Metastasis.

Cancer Cells rebel against the Body-Mind combination in a way that is similar to rebellion of a modern society against their government

Metastatic Cells: Once the in-situ cancer cells have damaged an organ, they try to enter the main blood stream via the Lymph nodes so that they can attack other organs of the body. The body's inherent defense mechanism usually detects these cells on time and kills a majority of them.

However, if the body's defense mechanism is not strong enough and a few cancerous cells slip through, they start to settle down at a new organ and multiply fast. This process is knowns as colonization. Such newly infected organs also start to malfunction after some time, and cancer is now said to have spread within the body.

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