Arne Staby - Preparative Chromatography for Separation of Proteins

1. Chapter 02
2. Chapter 03
3. Chapter 04
4. Chapter 06
5. Chapter 10
6. Chapter 11
7. Chapter 12
8. Chapter 13
9. Chapter 14
10. Chapter 15
11. Chapter 16
12. Chapter 17
13. Chapter 18

1. Chapter 01
2. Chapter 02
3. Chapter 03
4. Chapter 04
5. Chapter 05
6. Chapter 06
7. Chapter 07
8. Chapter 08
9. Chapter 09
10. Chapter 10
11. Chapter 11
12. Chapter 12
13. Chapter 13
14. Chapter 14
15. Chapter 15
16. Chapter 16
17. Chapter 17
18. Chapter 18

Significant advancements in the fields of biology, chemistry, and related disciplines have led to a barrage of major accomplishments in the field of biotechnology. Wiley Series in Biotechnology and Bioengineering focuses on showcasing these advances in the form of timely, cuttingedge textbooks and reference books that provide a thorough treatment of each respective topic.

Topics of interest to this series include, but are not limited to, protein expression and processing; nanotechnology; molecular engineering and computational biology; environmental sciences; food biotechnology, genomics, proteomics and metabolomics; largescale manufacturing and commercialization of human therapeutics; biomaterials and biosensors; and regenerative medicine. We expect these publications to be of significant interest to the practitioners both in academia and industry. Authors and editors were carefully selected for their recognized expertise and their contributions to the various and farreaching fields of biotechnology.

Preparative Chromatography for Separation of Proteins
by Arne Staby, Anurag S. Rathore, Satinder (Sut) Ahuja

Vaccine Development and Manufacturing
by Emily P. Wen (Editor), Ronald Ellis (Editor), Narahari S. Pujar (Editor)

Risk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing
by Hamid Mollah (Editor), Harold Baseman (Editor), Mike Long (Editor)

Emerging Cancer Therapy: Microbial Approaches and Biotechnological Tools
by Arsenio Fialho (Editor), Ananda Chakrabarty (Editor)

Quality by Design for Biopharmaceuticals: Principles and Case Studies
by Anurag S. Rathore (Editor), Rohin Mhatre (Editor)

Edited by
Arne Staby, Anurag S. Rathore, and Satinder Ahuja

Copyright 2017 by John Wiley & Sons, Inc. All rights reserved

Published by John Wiley & Sons, Inc., Hoboken, New Jersey

Published simultaneously in Canada

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Library of Congress CataloginginPublication Data:

Names: Staby, Arne, 1964 editor. | Rathore, Anurag S. (Anurag Singh), 1973 editor. | Ahuja, Satinder, 1933 editor.
Title: Preparative chromatography for separation of proteins / edited by Arne Staby, Anurag S. Rathore, Satinder Ahuja.
Description: Hoboken, New Jersey : John Wiley & Sons Inc., [2017] | Series: Wiley series in biotechnology and bioengineering | Includes bibliographical references and index.
Identifiers: LCCN 2016042817 | ISBN 9781119031109 (hardback) | ISBN 9781119031154 (epub)
Subjects: LCSH: Chromatographic analysis. | Separation (Technology) |
BISAC: TECHNOLOGY & ENGINEERING / Chemical & Biochemical. |
SCIENCE / Life Sciences / Biochemistry. | SCIENCE / Chemistry / Analytic.
Classification: LCC QD272.C4 P75 2017 | DDC 572/.64028dc23
LC record available at https://lccn.loc.gov/2016042817

Set in 10/12pt Warnock by SPi Global, Pondicherry, India

Cover Design: WileyCover Image Credit: Courtesy of L. Sejergaard, H. Ahmadian, T.B. Hansen, A. Staby, and E.B. Hansen.

Haleh Ahmadian
Protein Purification Technology, Novo Nordisk A/S, Mlv, Denmark

Satinder Ahuja
Ahuja Consulting, Calabash, NC, USA

Niklas Andersson
Chemical Engineering, Lund University, Lund, Sweden

Chris Antoniou
Biogen, Cambridge, MA, USA

Suvrajit Banerjee
Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA

Marc Bisschops
Pall Corporation, Medemblik, the Netherlands

Martin P. Breil
DAPI Modelling & Optimization, Novo Nordisk A/S, Bagsvrd, Denmark

Nina Brestrich
Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute for Technology, Karlsruhe, Germany

Mark Brower
Merck & Co., Inc., Kenilworth, NJ, USA

Steven Cramer
Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA

Patrick Diederich
Peptide & Protein Purification, Novo Nordisk A/S, Bagsvrd, Denmark

Sren S. Frederiksen
Mathematical Modelling, Novo Nordisk A/S, Bagsvrd, Denmark

Ernst B. Hansen
Mathematical Modelling, Novo Nordisk A/S, Bagsvrd, Denmark

Thomas B. Hansen
Mathematical Modelling, Novo Nordisk A/S, Bagsvrd, Denmark

Sigrid Hansen
Protein Purification Development, Novo Nordisk A/S, Gentofte, Denmark

Milton T. W. Hearn
Victorian Centre for Sustainable Chemical Manufacturing, Monash University, Melbourne, Australia