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Jerome B. Posner - Plum and Posner’s Diagnosis and Treatment of Stupor and Coma

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Jerome B. Posner Plum and Posner’s Diagnosis and Treatment of Stupor and Coma

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Detailed overview of the theory of human consciousness for clinicians who deal with disorders of consciousness but are not neuroscientistsPractical organization of the examination of the comatose patient, a guide to differential diagnosis, and cutting edge neurocritical care treatmentDetailed discussions of brain death, recovery from minimally conscious state, and ethics of comaNew to this Edition:This edition includes new chapters on the treatment of comatose patients, both initially in the Emergency Department, and later in the ICUThe chapters on recovery from minimally conscious state and on ethics have been extensively rewrittenThe chapters on diagnosis of coma have been updated to reflect the rapidly changing data on brain circuitry and causes of loss of consciousnessPlum and Posners Diagnosis and Treatment of Stupor and Coma, 5th edition, is a major update of the classic work on diagnosing the cause of coma, with the addition of completely new sections on treatment of comatose patients, by Dr. Jan Claassen, the Director of the Neuro-ICU at Columbia New York Presbyterian Hospital. The first chapter of the book provides an up-to-date review on the brain mechanisms that maintain a conscious state in humans, and how lesions that damage these mechanisms cause loss of consciousness or coma. The second chapter reviews the neurological examination of the comatose patient, which provides the basis for determining whether the patient is suffering from a structural brain injury causing the coma, or from a metabolic disorder of consciousness. The third and fourth chapters review the pathophysiology of structural lesions causing coma, and the specific disease states that result in coma. Chapter five is a comprehensive treatment of the many causes of metabolic coma. Chapter 6 review psychiatric causes of unresponsiveness and how to identify and treat them. Chapters 7 and 8 review the overall emergency treatment of comatose patients, followed by the treatment of specific causes of coma. Chapter 9 examines the long term outcomes of coma, including the minimally conscious state and the persistent vegetative state, and how they can be distinguished, and their implications for eventual useful recovery. Chapter 10 reviews the topic of brain death and the standards for examination of a patient that are required to make the determination of brain death. The final chapter 11 is by J.J. Fins, a medical ethicist who was invited by the other authors to write an essay on the ethics of diagnosis and treatment of patients who, by definition, have no way to approve of or communicate about their wishes.While providing detailed background for neurological and neurosurgical specialists, the practical nature of the material in this book has found its greatest use among Internists, Emergency Medicine, and Intensive Care specialists, who deal with comatose patients frequently, but who may not have had extensive neurological training.

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Advance Praise for Plum and Posners Diagnosis and Treatment of Stupor and Coma - photo 1
Advance Praise for Plum and Posners Diagnosis and Treatment of Stupor and Coma

Facing patients with impaired consciousness or coma is among the most urgent and difficult medical emergencies. The 1966 first edition of the Diagnosis of Stupor and Coma by Plum and Posner illuminated medical science with an orderly approach in dealing with the comatose patient. In this fifth edition, Saper and colleagues provide a concise state of the art update of this topic necessary for patient care and is a must read for all health care providers who wish to acquire or hone their knowledge to care for these patients.

David A. Hafler, MD, William S. and Lois Stiles Edgerly Professor of Neurology and Immunobiology, Chairman, Department of Neurology, Yale School of Medicine, Neurologist-in-Chief, Yale New Haven Hospital, CT

Plum and Posners Diagnosis and Treatment of Stupor and Coma has long provided the best description of both the pathophysiology and the diagnostic approach to disorders of consciousness. Remarkably, this edition was able to integrate the many new diagnostic and therapeutic tools that have become available while still maintaining the clarity and logic that made the book so useful. Every neurologist should read it!

John Kessler, MD, Davee Professor, Davee Department of Neurology, Northwestern University, Chicago, IL

This new 5th Edition of the seminal Plum and Posners Stupor and Coma contributed by a brilliant, and partly renewed, band associating Posner, Saper, Schiff, and Claassen is not a USA dormant cop (anagram of the title), but a worldwide must-read for all those interested by the neurology, physiology and anatomy of consciousness, and by its disorders. Keeping with the very insightful and hitherto unseen tone of the 1972 first edition, this new opus covers almost exhaustively the rich and fast-growing relevant literature, and it can be read at different levels of expertise ranging from fresh college students to emeritus professors, including active neurologists, intensivists, and medical practitioners.

Prof. Lionel Naccache, Sorbonne University, Piti-Salptrire Hospital, Paris, France

As both the authoritative text on the subject, and compulsory reading for all neurologists, neurosurgeons, intensivists and ER physicians, the 5th edition of Plum and Posners Diagnosis and Treatment of Stupor and Coma is as indelible a contribution as its four prior editions. Continuing in the tradition of the first editions 1966 grounding in brain structure-function relationships as they apply to disorders of consciousness, this edition is a welcome update to 2007s 4th edition capturing important advances in knowledge in the field. It is a comprehensive, yet succinct, well referenced, scholarly summary of our present day understanding of the molecular basis of consciousness as much as it is a practical clinicians guide to evaluation, treatment, and prognosis. A triumphindeed! A wonderful and necessary addition to the bookshelf of a wide audience whose interests include the brains role in modulating normal and disturbed states of consciousness.

David B. Rye, MD, PhD, Professor of Neurology, Emory University School of Medicine, Atlanta, GA

This new edition provides a comprehensive update of a classic and essential text. It preserves the best elements of the originalthe succinct formulation of the pathophysiology of coma, the approach to examining a comatose patientbut brings the book solidly into the 21st Century with inclusion of modern technologies and methods. The expanded discussion of the treatment of comatose patients is most welcome, delivering a wealth of information in a concise format. This remains a remarkable book: at once both comprehensive and accessible, equally suitable for extended study and as a quick bedside reference. It deserves a place in the library of every practicing neurologist.

David G. Standaert, MD, PhD, John N. Whitaker Professor and Chair, Department of Neurology, The University of Alabama at Birmingham, AL

SERIES EDITOR

Eva Feldman, MD, PhD, FAAN, FANA

Russell N. DeJong Professor of Neurology

University of Michigan

Contemporary Neurology Series

PRINCIPLES OF DRUG THERAPY IN NEUROLOGY

Second Edition

Michael V. Johnston, MD, and Robert A. Gross, MD, PhD, Editors

NEUROLOGIC COMPLICATIONS OF CANCER

Second Edition

Lisa M. DeAngelis, MD, and Jerome B. Posner, MD

NEUROLOGIC COMPLICATIONS OF CRITICAL ILLNESS

Third Edition

Eelco F.M. Wijdicks, MD, PhD, FACP

CLINICAL NEUROPHYSIOLOGY

Third Edition

Jasper R. Daube, MD, and Devon I. Rubin, MD, Editors

PERIPHERAL NEUROPATHIES IN CLINICAL PRACTICE

Steven Herskovitz, MD, Stephen N. Scelsa, MD, and Herbert H. Schaumburg, MD

CLINICAL NEUROPHYSIOLIOGY OF THE VESTIBULAR SYSTEM

Fourth Edition

Robert W. Baloh, MD, FAAN, and Kevin A. Kerber, MD

THE NEURONAL CEROID LIPOFUSCINOSES (BATTEN DISEASE)

Second Edition

Sara E. Mole, PhD, Ruth D. Williams, MD, and Hans H. Goebel, MD, Editors

PARANEOPLASTIC SYNDROMES

Robert B. Darnell, MD, PhD, and Jerome B. Posner, MD

JASPERS BASIC MECHANISMS OF THE EPILEPSIES

Jeffrey L. Noebels, MD, PhD, Massimo Avoli, MD, PhD, Michael A. Rogawski, MD, PhD, Richard W. Olsen, PhD, and Antonio V. Delgado-Escueta, MD

MYASTHENIA GRAVIS AND MYASTHENIC DISORDERS

Second Edition

Andrew G. Engel, MD

MOLECULAR PHYSIOLOGY AND METABOLISM OF THE NERVOUS SYSTEM

Gary A. Rosenberg, MD

SEIZURES AND EPILEPSY

Second Edition

Jerome Engel, Jr., MD, PhD

MULTIPLE SCLEROSIS

Moses Rodriguez, MD, Orhun H. Kantarci, MD, and Istvan Pirko, MD

FRONTOTEMPORAL DEMENTIA

Bruce L. Miller, MD

AUTONOMIC NEUROLOGY

Eduardo E. Benarroch, MD

EVALUATION AND TREATMENT OF MYOPATHIES

Second Edition

Emma Ciafaloni, MD, Patrick F. Chinnery, FRCP, FMedSci, and Robert C. Griggs, MD, Editors

MOTOR NEURON DISEASE IN ADULTS

Mark Bromberg, MD

HYPERKINETIC MOVEMENT DISORDERS

Roger M. Kurlan, MD, Paul E. Green, MD, and Kevin M. Biglan, MD, MPH

THE NEUROLOGY OF EYE MOVEMENTS

Fifth Edition

R. John Leigh, MD, FRCP, and David S. Zee, MD

MIGRAINE

Third Edition

David W. Dodick, MD, and Stephen D. Silberstein, MD, FACP, FAHS, FAAN

CLINICAL NEUROPHYSIOLOGY

Fourth Edition

Devon Rubin and Jasper Daube, Editors

Oxford University Press is a department of the University of Oxford It - photo 2

Oxford University Press is a department of the University of Oxford. It furthers the Universitys objective of excellence in research, scholarship, and education by publishing worldwide. Oxford is a registered trade mark of Oxford University Press in the UK and certain other countries.

Published in the United States of America by Oxford University Press

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Oxford University Press 2019

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Oxford University Press, or as expressly permitted by law, by license, or under terms agreed with the appropriate reproduction rights organization. Inquiries concerning reproduction outside the scope of the above should be sent to the Rights Department, Oxford University Press, at the address above.

You must not circulate this work in any other form and you must impose this same condition on any acquirer.

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