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Bill Sullivan - Pleased to Meet Me: Genes, Germs, and the Curious Forces That Make Us Who We Are

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Bill Sullivan Pleased to Meet Me: Genes, Germs, and the Curious Forces That Make Us Who We Are
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Why are you attracted to a certain type? Why are you a morning person? Why do you vote the way you do? From a witty new voice in popular science comes a life-changing look at what makes you you.I cant believe I just said that. What possessed me to do that? Whats wrong with me? Were constantly seeking answers to these fundamental human questions, and now, science has the answers. Clever, relatable, and revealing, this eye-opening narrative from Indiana University School of Medicine professor Bill Sullivan explores why we do the things we do through the lens of genetics, microbiology, psychology, neurology, and family history. From what we love (and hate) to eat and who we vote for in political elections to when we lose our virginity and why some people find drugs so addicting, this illuminating book uses the latest scientific research to unveil the secrets of what makes us tick. Filled with fascinating insights--including how experiences that haunted our grandparents echo in our DNA, why the bacteria in our guts mess with our minds, and whether there really is a murder gene--Pleased to Meet Me explains the hidden forces shaping who we are, pointing us on a path to how we might become our best selves.

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Contents
Published by National Geographic Partners LLC 1145 17th Street NW Washington - photo 1
Published by National Geographic Partners LLC 1145 17th Street NW Washington - photo 2

Published by National Geographic Partners, LLC

1145 17th Street NW Washington, DC 20036

Copyright 2019 William J. Sullivan, Jr. All rights reserved. Reproduction of the whole or any part of the contents without written permission from the publisher is prohibited.

NATIONAL GEOGRAPHIC and Yellow Border Design are trademarks of the National Geographic Society, used under license.

Library of Congress Cataloging-in-Publication Data

Names: Sullivan, Bill (William J.), 1970- author.

Title: Pleased to meet me : how genes, germs, and the environment make us who we are / Bill Sullivan.

Description: Washington, D.C. : National Geographic, [2019]
Includes bibliographical references and index.

Identifiers: LCCN 2018052230 (print) | LCCN 2018054545 (ebook) | ISBN 9781426220562 (eBook) | ISBN 9781426220555 (hardcover)

Subjects: LCSH: Epigenetics. | Neurogenetics.

Classification: LCC QH450 (ebook) | LCC QH450 .S85 2019 (print) | DDC 572.8/65dc23

LC record available at https://lccn.loc.gov/2018052230

Since 1888, the National Geographic Society has funded more than 13,000 research, exploration, and preservation projects around the world. National Geographic Partners distributes a portion of the funds it receives from your purchase to National Geographic Society to support programs including the conservation of animals and their habitats.

Get closer to National Geographic explorers and photographers, and connect with our global community. Join us today at nationalgeographic.com/join

For rights or permissions inquiries, please contact National Geographic Books Subsidiary Rights:

Interior design: Nicole Miller

Ebook ISBN9781426220562

v5.4

a

To my kids, Colin and Sophia.

Theres a lot of me that I see in you.

At least you got some good traits from your mother.

CONTENTS

ADVANCE PRAISE FOR

PLEASED TO MEET ME

From microbes that make you intoxicated to the genetic demons hiding within your DNA, Pleased to Meet Me is a whirlwind journey through human biology. Deftly weaving cutting-edge science with popular culture, this accessible book will leave you wanting more.

SHARON MOALEM, M.D., PH.D. , author of Survival of the Sickest

A rare treat: A book thats fun to read from cover to cover, while leaving you wiser and better-informed about who you really are.

ADAM ALTER, PH.D. , author of Drunk Tank Pink and Irresistible

Bill Sullivan is a sympathetic guide who understands your dislike of exercise and most things healthy. This wide-ranging tome puts a new light on human pursuits, including eating, drinking, thinking, sex, free will, even politics and religions, all presented with topical humor and wit.

SCOTT ANDERSON , co-author of The Psychobiotic Revolution

Bill Sullivan artfully reports on how our genes interact with our surroundings to shape our unique personalities and the people weve become.

A beautiful melding of science and the human experience.

PETER HOTEZ, M.D., PH.D. , author of Vaccines Did Not Cause Rachels Autism

Pleased to Meet Me is as close to philosophy as science books get. Infused with Sullivans witty voice, the book exposes us as the biological machines we really are. Youll be quoting it to your friends.

ALANNA COLLEN, PH.D. , author of 10% Human

Pleased to Meet Me makes you see the world in a new way.

We like to think were totally in control of how we think and act, but Sullivan makes a strong case that our beloved agency is not what we think it is.

MATTHEW SIMON , Wired science writer and author of Plight of the Living Dead

INTRODUCTION
MEET THE REAL YOU

People do the strangest things, dont they?

But no matter how normal you think you are, there are people out there who think youre the oddball. From our diet to our habits to our beliefs, humanity is gloriously diverse.

How does this play out? Well, some people enjoy exotic foods and fine wine; others want nothing more than a plain hamburger and a Bud Light. Some people are vegetarians whereas others say that brussels sprouts taste like fart truffles. Some people stay thin throughout their lives; others feel their thighs widening just thinking about cheesecake. Some like to work out, and others would rather chill out.

We are collectively diverse in our habits as well. Some people wear sports jerseys and war paint to root for the home team; others would rather cosplay as a Borg at a Star Trek convention. Some live for a wild night on the town, and others prefer a night at the museum. Some people like to globe-trot; others wont even venture out to World Market. Some people are fashionable, and others would wear down the hosts of What Not to Wear.

And what about our behavior? Alcohol and drugs have no pull over some, but others cannot escape their gravity. Some people are always honest, yet others will lie, cheat, and steal with no remorse. Some people are color-blind; others only want to see white. Some wouldnt hurt a fly, while others fly off the handle. Some fight for war, others fight for peace.

The same is true of our romantic inclinations. Some people are faithful to their partners; others pretend to be. Some bank on good looks and money, while others are more invested in whats below the surface. Some people want a soul mate to love for the rest of time; others would view that as a life sentence. Some people remember anniversaries; some people are forgetful.

And what of our very natures? Some people are kind, and others are mean. Some have boundless energy, while some seem lazy. Some are fearless, and some are scared of their own shadow. Some always see the glass as half full; others always see it as half empty and leaking.

And between all of these extremes are many people who fall somewhere in the middle. We are all flesh and bloodbut what tremendous variability in how we live our lives! Nevertheless, I trust we have one thing in common: a desire to understand why each of us is so spectacularly different.


T HROUGH THE AGES , people have watched as philosophers, theologians, self-help gurus, and Frasier Crane have attempted to tackle the mysteries of human behavioroften with limited success. But practical answers to the questions of why we are who we are and do the things we do are coming from an unexpected source: research laboratories.

Scientists have recently learned a great deal about us: deep, dark secrets that everyone needs to know. The better you know your true self, the easier it is to navigate lifes journey. And, by knowing what makes people tick, you will have a better understanding of those who are not like you.

All of us like to think that we march to the beat of our own drum. But science has revealed that the rhythm is played by percussionists we cant see with the naked eye. We march through life believing that were the drummerbut the shocking evidence reveals this is an illusion. The truth is that there are hidden forces orchestrating our each and every move.

To illustrate this point, lets consider one of my personal quirks: my distaste for vegetables like broccoli. Ive always hated broccoli because it tastes so bitter to me; the smell of it cooking can make me gag. My wife, however, eats a lot of it. Willingly! Whats the difference between us? A clue comes from how our children responded to broccoli as infants: My son liked it, but my daughter reacted as if we were trying to poison her. We did not teach our children to love or loathe broccoli; they came to us this way, suggesting that this behavior is written in our DNA (well spell out how this works in ).

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