Eben Kirksey - The Mutant Project: Inside the Global Race to Genetically Modify Humans
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- Book:The Mutant Project: Inside the Global Race to Genetically Modify Humans
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An anthropologist visits the frontiers of genetics, medicine, and technology to ask: Whose values are guiding gene editing experiments? And what does this new era of scientific inquiry mean for the future of the human species?
That rare kind of scholarship that is also a page-turner.--Britt Wray, author of Rise of the Necrofauna At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies--twin girls named Lulu and Nana--sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for illegal medical practice. As scientists elsewhere start to catch up with Chinas vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake: Who gets access to gene editing technologies? As countries loosen regulations around the globe, from the U.S. to Indonesia, can we shape research agendas to promote an ethical and fair society? Eben Kirksey takes us on a groundbreaking journey to meet the key scientists, lobbyists, and entrepreneurs who are bringing cutting-edge genetic engineering tools like CRISPR--created by Nobel Prize-winning biochemists Jennifer Doudna and Emmanuelle Charpentier--to your local clinic. He also ventures beyond the scientific echo chamber, talking to disabled scholars, doctors, hackers, chronically-ill patients, and activists who have alternative visions of a genetically modified future for humanity. The Mutant Project empowers us to ask the right questions, uncover the truth, and navigate this brave new world.Eben Kirksey: author's other books
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TO LULU AND NANA
1818 | Mary Shelleys Frankenstein, the worlds first science fiction novel, depicts a young researcher who produces a creature with superhuman powers. |
1869 | Charles Darwin publishes On the Origin of Species. |
1901 | The Mutation Theory, by Hugo de Vries, introduces foundational ideas about genetic variation and evolutionary change. |
1953 | James Watson and Francis Crick claim to have discovered the secret of life with DNAs double-helix structure, after sneaking a peek of an X-ray diffraction photograph taken by Rosalind Franklin. |
1963 | The X-Men debut in a Marvel Comics series as mutant superheroes fighting for equality and justice. |
1978 | The worlds first test-tube baby, Louise Brown, is born in England. |
1987 | CRISPR, or clustered regularly interspaced short palindromic repeats, is discovered by Yoshizumi Ishino in bacteria. The function is unknown. |
2000 | President Bill Clinton unveils preliminary findings from the Human Genome Project, saying, Human beings, regardless of race, are 99.9% the same. |
6.2012 | Jennifer Doudna and Emmanuelle Charpentier demonstrate how to modify DNA with CRISPR. |
4.2015 | Genetically modified human embryos created with CRISPR are reported from Junjiu Huangs laboratory in Guangzhou, China. |
6.2016 | The first CRISPR clinical trial in the United States secures initial approval from a government panel. |
2016 | Stranger Things, describing secret government experiments on children with uncanny powers, debuts on Netflix. |
9.2016 | The China National GeneBank opens with the goal of collecting DNA from every human on earth. |
10.2017 | President Jinping Xi gives his China Dream speech, calling on the country to prioritize innovation with cutting-edge frontier technologies. |
2018 | Dr. Jiankui He implants a genetically engineered embryo into its mothers womb in January, but it fails to take. After a number of attempts, a woman known as P6 becomes pregnant in March. |
10.2018 | Lulu and Nana, the worlds first edited babies, are born in mainland China. |
12.2018 | News of the birth leaks as the Second International Summit on Human Genome Editing opens in Hong Kong. |
12.2019 | Dr. Hes three-year prison sentence is announced. |
Surreal artwork in the hotel lobbya gorilla peeking out of a peeled orange, smoking a cigarette; an astronaut riding a cyborg-giraffewas the backdrop for bombshell news rocking the world. In November 2018 Hong Kongs Le Mridien Cyberport hotel became the epicenter of controversy about Jiankui He, a Chinese researcher who was staying there when a journalist revealed he had created the worlds first edited babies. Select experts were gathering in the hotel for the Second International Summit on Human Genome Editinga meeting that had been called to deliberate about the future of the human species. As CNN deemed the experiment monstrous, as heated discussions took place in labs and living rooms around the globe, Dr. He sat uncomfortably on a couch in the lobby.
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