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Peter Lee - The AI Revolution in Medicine: GPT-4 and Beyond

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Peter Lee The AI Revolution in Medicine: GPT-4 and Beyond

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AI is about to transform medicine. Heres what you need to know right now.

The development of AI is as fundamental as the creation of the personal computer. It will change the way people work, learn, and communicate--and transform healthcare. But it must be managed carefully to ensure its benefits outweigh the risks. Im encouraged to see this early exploration of the opportunities and responsibilities of AI in medicine.

--Bill Gates

Just months ago, millions of people were stunned by ChatGPTs amazing abilities -- and its bizarre hallucinations. But that was 2022. GPT-4 is now here: smarter, more accurate, with deeper technical knowledge. GPT-4 and its competitors and followers are on the verge of transforming medicine. But with lives on the line, you need to understand these technologies -- stat.

What can they do? What cant they do -- yet? What shouldnt they ever do? To decide, experience the cutting edge for yourself. Join three insiders whove had months of early access to GPT-4 as they reveal its momentous potential -- to improve diagnoses, summarize patient visits, streamline processes, accelerate research, and much more. Youll see real GPT-4 dialogues -- unrehearsed and unfiltered, brilliant and blundering alike -- all annotated with invaluable context, candid commentary, real risk insights, and up-to-the-minute takeaways.

  • Preview a day in the life of a doctor with a true AI assistant.
  • See how AI can enhance doctor-patient encounters at the bedside and beyond.
  • Learn how modern AI works, why it can fail, and how it can be tested to earn trust.
  • Empower patients: improve access and equity, fill gaps in care, and support behavior change.
  • Ask better questions and get better answers with prompt engineering.
  • Leverage AI to cut waste, uncover fraud, streamline reimbursement, and lower costs.
  • Optimize clinical trials and accelerate cures with AI as a research collaborator.
  • Find the right guardrails and gain crucial insights for regulators and policymakers.
  • Sketch possible futures: What dreams may come next?

There has never been technology like this. Whether youre a physician, patient, healthcare leader, payer, policymaker, or investor, AI will profoundly impact you -- and it might make the difference between life or death. Be informed, be ready, and take charge -- with this book.

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The development of AI is as fundamental as the creation of the personal computer. It will change the way people work, learn, and communicateand transform healthcare. AI is already being used to improve how diseases are detected and diagnosed. In the future, it will help accelerate research breakthroughs and make accurate, reliable medical advice available to those who never get to see a doctor. AI is a powerful tool that can reduce inequity and improve life for millions of people around the world. But it must be managed carefully to ensure its benefits outweigh the risks. Im encouraged to see this early exploration of the opportunities and responsibilities of AI in medicine.

Bill Gates

The AI Revolution in Medicine: GPT-4 and Beyond
The AI Revolution in Medicine: GPT-4 and Beyond

BY PETER LEE, CAREY GOLDBERG, AND ISAAC KOHANE WITH SBASTIEN BUBECK

The AI Revolution in Medicine GPT-4 and Beyond Lee Goldberg Kohane - photo 3

The AI Revolution in Medicine: GPT-4 and Beyond (Lee, Goldberg, Kohane)

Published by: Pearson Education, Inc.

Copyright 2023 by Peter Lee, Carey Goldberg, Isaac Kohane

Cover art by Leyn / Shutterstock

All rights reserved. This publication is protected by copyright, and permission must be obtained from the publisher prior to any prohibited reproduction, storage in a retrieval system, or transmission in any form or by any means, electronic, mechanical, photocopying, recording, or likewise. For information regarding permissions, request forms, and the appropriate contacts within the Pearson Education Global Rights & Permissions Department, please visit www.pearson.com/permissions.

No patent liability is assumed with respect to the use of the information contained herein. Although every precaution has been taken in the preparation of this book, the publisher and author assume no responsibility for errors or omissions. Nor is any liability assumed for damages resulting from the use of the information contained herein.

ISBN-13: 978-0-13-820013-8

ISBN-10: 0-13-820013-0

Library of Congress Control Number: 2023934948

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Pearsons Commitment to Diversity, Equity, and Inclusion

Pearson is dedicated to creating bias-free content that reflects the diversity of all learners. We embrace the many dimensions of diversity, including but not limited to race, ethnicity, gender, socioeconomic status, ability, age, sexual orientation, and religious or political beliefs.

Education is a powerful force for equity and change in our world. It has the potential to deliver opportunities that improve lives and enable economic mobility. As we work with authors to create content for every product and service, we acknowledge our responsibility to demonstrate inclusivity and incorporate diverse scholarship so that everyone can achieve their potential through learning. As the worlds leading learning company, we have a duty to help drive change and live up to our purpose to help more people create a better life for themselves and to create a better world.

Our ambition is to purposefully contribute to a world where:

  • Everyone has an equitable and lifelong opportunity to succeed through learning.

  • Our educational products and services are inclusive and represent the rich diversity of learners.

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To our children, in hopes they will have the healthcare imagined in this book

Authors Note

This book is a work in progress.

First, because AI entities like GPT-4 themselves are advancing so rapidly that the AI-human dialogues we use here inevitably become outdated within weeks.

And second, because this book is only an initial foray into one area medicine of what we expect to become a humanity-wide discussion about how best to harness the astonishing AI capabilities now emerging.

We hope, however, that it can serve as a model for ways to launch that discussion: It is based on extensive, carefully analyzed interactions with the AI. It lays out well-documented strengths and weaknesses. And it just barely begins to grapple with the urgent question: Given all this, what is to be done, long-term and right now?

About the text:

GPT-4 responses have often been shortened but never altered.

Zak and Peter bring their professional expertise to their writing but neither Harvard Medical School, Microsoft, nor OpenAI had any editorial control over this book.

Foreword

by Sam Altman

Early in the development of GPT-4, Kevin Scott, Microsofts Chief Technology Officer, and I decided to grant early experimental access to a small number of people, hoping to gain some understanding of its implications in a few key areas. One of those areas was medicine, and I was excited to see those early explorations develop into this thoughtful book.

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