AATIF M. HUSAIN - Practical Epilepsy

E DITOR

A ATIF M. H USAIN , MD

Department of Neurology
Duke University Medical Center
Durham, North Carolina

Neurodiagnostic Center
Veterans Administration Medical Center
Durham, North Carolina

Visit our website at www.demosmedical.com

ISBN: 9781620700297

e-book ISBN: 9781617051876

Acquisitions Editor: Beth Barry

Compositor: Exeter Premedia Services Private Ltd., Chennai

2016 Demos Medical Publishing, LLC. All rights reserved. This book is protected by copyright. No part of it may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher.

Medicine is an ever-changing science. Research and clinical experience are continually expanding our knowledge, in particular our understanding of proper treatment and drug therapy. The authors, editors, and publisher have made every effort to ensure that all information in this book is in accordance with the state of knowledge at the time of production of the book. Nevertheless, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the contents of the publication. Every reader should examine carefully the package inserts accompanying each drug and should carefully check whether the dosage schedules mentioned therein or the contraindications stated by the manufacturer differ from the statements made in this book. Such examination is particularly important with drugs that are either rarely used or have been newly released on the market.

Library of Congress Cataloging-in-Publication Data

Practical epilepsy / [edited by] Aatif M. Husain.

p. ; cm.

Includes bibliographical references and index.

ISBN 978-1-62070-029-7ISBN 978-1-61705-187-6 (e-book)

I. Husain, Aatif M., editor.

[DNLM: 1. Epilepsy. WL 385]

RC372

616.853dc23

2015014559

Printed in the United States of America by Bradford and Bigelow.

15 16 17 18 / 5 4 3 2 1

This book is dedicated to my wife, Sarwat Mohsin Husain, who gives so much
and asks for so little. Without her, there would be nothing.

Cheolsu Shin

Elizabeth K. Ruzzo, Rodney A. Radtke, David B. Goldstein, and Erin L. Heinzen

Matthew W. Luedke and Rodney A. Radtke

Richard P. Morse

William B. Gallentine

Sanjeev V. Kothare

Amit Verma

Pradeep Sahota

Aatif M. Husain and Abeer J. Hani

Saurabh R. Sinha

Aatif M. Husain

Rajdeep Singh

Robbie D. Buechler

Keith E. Dombrowski

Tung T. Tran

Dinesh V. Raju and Mohamad A. Mikati

Abeer J. Hani and Aatif M. Husain

Saurabh R. Sinha

Sandra Serafini, Merlise Clyde, Aatif M. Husain, and Michael Haglund

Matthew W. Luedke and William B. Gallentine

Jorge Oldan, Terence Wong, and Jeffrey Petrella

Adriana Palade

Phillip D. Ruppert and Sarah E. Cook

Saurabh R. Sinha

Christa B. Swisher and Rodney A. Radtke

Jos E. Cavazos

Kathryn Idol Xixis, Roha Khalid, and Mohamad A. Mikati

Cesar C. Santos

K. Nicole Mims and Aatif M. Husain

William B. Gallentine

Edgar Perez and Gerald Grant

Candace Richardson and William B. Gallentine

William L. Bell

Keith E. Dombrowski

Lynn Liu

Christa B. Swisher and Aatif M. Husain

Jonathan J. Halford

Sarah K. Rivelli

David M. Labiner

Abeer J. Hani and Mohamad A. Mikati

Timothy A. Collins

Erick N. Viorritto and Sujay M. Kansagra

Abeer J. Hani and Rodney A. Radtke

Susan Hollar and Deborah LaBelle-Scarfo

William L. Bell, MD

Professor and Director of Comprehensive Epilepsy Center

Department of Neurology

Georgetown University

Washington, DC

Robbie D. Buechler, MD, PhD

Neurologist

Department of Neurosciences/Neurology

Novant Health Neurology Specialists

Matthews, North Carolina

Jos E. Cavazos, MD, PhD

Professor and Assistant Dean

Department of Neurology

University of Texas Health Science Center at San Antonio;

Staff Physician and Director

San Antonio VA Epilepsy Center of Excellence

South Texas Veterans Health Care System

San Antonio, Texas

Merlise Clyde, PhD

Professor

Department of Statistical Science

Duke University

Durham, North Carolina

Timothy A. Collins, MD

Associate Professor of Neurology

Chief, Division of Headache and Pain

Department of Neurology

Duke University Medical Center

Durham, North Carolina

Sarah E. Cook, PhD

Assistant Professor

Department of Psychiatry and Behavioral Sciences

Duke University

Durham, North Carolina

Keith E. Dombrowski, MD

Assistant Professor

Department of Neurology

Duke University Medical Center;

Neurologist

Department of Medicine

Durham VA Medical Center

Durham, North Carolina

William B. Gallentine, DO

Associate Professor

Division of Pediatric Neurology

Department of Pediatrics

Duke Childrens Hospital

Durham, North Carolina

David B. Goldstein, PhD

Professor

Department of Genetics and Development;

Director

Institute for Genomic Medicine

Columbia University Medical Center

New York, New York

Gerald Grant, MD

Associate Professor

Department of Neurosurgery

Stanford University

Stanford, California

Michael Haglund, MD, PhD

Professor

Division of Neurosurgery

Department of Surgery

Duke University Medical Center

Durham, North Carolina

Jonathan J. Halford, MD

Associate Professor of Neurology and Psychiatry

Department of Neurology

Medical University of South Carolina

Charleston, South Carolina

Abeer J. Hani, MD

Assistant Professor

Division of Pediatric Neurology

Department of Pediatrics

Gilbert and Rose-Marie Chagoury School of Medicine

Lebanese American University

Beirut, Lebanon

Erin L. Heinzen, PharmD, PhD

Assistant Professor

Department of Pathology;

Deputy Director

Institute for Genomic Medicine

Columbia University Medical Center