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Eustachio Nettis - Practical Guide to Patch Testing

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Book:
Practical Guide to Patch Testing
Author:
Eustachio Nettis / Gianni Angelini
Publisher:
Springer Nature
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Books / Children
Year:
2020
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This volume provides allergy and dermatology specialists with a practical guide to the correct patch test methodology for their day-to-day clinical practice: it includes the latest available hapten series (standard series and integrative series), the golden rules for concentration and conservation of the haptens themselves, and the indispensable test equipment. The book, coming in a handy softcover format, is also nicely illustrated with over 100 full color pictures and tables. The contents focus on the interpretation of the epicutaneous test reading as well, relating to clinical relevance of the reactions and granting a correct management of the allergic patient. Practical Guide to Patch Testing will be of great value to all practicing allergists or dermatologists and professionals related.

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Editors

Eustachio Nettis and Gianni Angelini

Practical Guide to Patch Testing

Editors

Eustachio Nettis

Allergist and Dermatologist, Regional Reference Center, University Allergology Clinic, Bari, Italy

Gianni Angelini

Professor of Dermatology, Former Professor and Chairman University of Bari Aldo Moro, Bari, Italy

ISBN 978-3-030-33872-5 e-ISBN 978-3-030-33873-2

https://doi.org/10.1007/978-3-030-33873-2

Partially based on the Italian language edition: Atlante e Compendio Il Patch Test, by E. Nettis and G.Angelini, Pacini-Editore Medicina, 2017. Pacini Editore

Springer Nature Switzerland AG 2020

This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.

The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG

The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

Patch tests are the elective tests done to confirm the diagnosis of a contact dermatitis. They are essential tools in allergological practice. Even today, they are still the only method that can confirm or exclude the clinical suspicion of allergic contact dermatitis, and directly identify the etiological agent.

Over the years, the importance of patch tests has grown continually to such an extent that nowadays the results of these tests are also valid in the medicolegal field as allergological proof of an occupational disease.

Thus, it is extremely important to have an in-depth knowledge of the principles and practical rules governing the performance of these tests in order to obtain valid, reliable results and above all to offer the patient adequate guidance since the resolution of the disease and prevention of recurrence depend first and foremost on avoiding exposure to the substance responsible for the allergic manifestation.

This Atlas has the aim of providing specialists with a useful tool that can help them to gain experience of the correct methodology for performing patch tests. It offers an accurate information about the hapten series currently available (standard series and integrated series), their concentrations and correct preservation methods, as well as about the apparatus to be used to administer various tests. The vital aspects of reading and interpretation of the patch tests are closely analyzed, in view of the different clinical relevance of the possible reactions, in order to ensure the correct management of patients suffering from contact allergy.

Eustachio Nettis

Gianni Angelini

Bari, Italy

Acknowledgment

Thanks for the irreplaceable collaboration to

Lucia Masciopinto, MD. Trainee Doctor in Allergology and Clinical Immunology

Stefania Magist, MD. Trainee Doctor in Allergology and Clinical Immunology

Elisabetta Di Leo, MD, PhD. Specialist in Allergology and Clinical ImmunologyPhD in Clinical Immunology

Maria Giovanna Priore, MD. Specialist in Allergology and Clinical Immunology

Contents

Gianni Angelini and Eustachio Nettis

Eustachio Nettis , Domenico Bonamonte and Gianni Angelini

Eustachio Nettis , Caterina Foti , Daniele Paolo Pigatto , Alberico Motolese and Gianni Angelini

Eustachio Nettis and Gianni Angelini

Gianni Angelini and Eustachio Nettis

Contributors

Gianni Angelini

Dermatology, University of Bari Aldo Moro, Bari, Italy

Domenico Bonamonte

Department of Biomedical Science and Human Oncology, University of Bari Aldo Moro, Bari, Italy

Caterina Foti

Department of Biomedical Science and Human Oncology, University of Bari Aldo Moro, Bari, Italy

Alberico Motolese

Department of Dermatology, Macchi Hospital, Varese, Italy

Eustachio Nettis

Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

Daniele Paolo Pigatto

Department of Medical, Surgical and Dental Biosciences, Galeazzi Hospital, University of Milan, Milan, Italy

Springer Nature Switzerland AG 2020

E. Nettis, G. Angelini (eds.) Practical Guide to Patch Testing https://doi.org/10.1007/978-3-030-33873-2_1

1. Contact Dermatitis

Gianni Angelini

(1)

Dermatology, University of Bari Aldo Moro, Bari, Italy

(2)

Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

Gianni Angelini

Email:

Eustachio Nettis (Corresponding author)

Email:

Keywords

Contact dermatitis Irritant contact dermatitis Allergic contact dermatitis Prevalence Airborne contact Endogenous contact

As the shock-absorbing organ, the skin is the first line of defense against the various aggressive exogenous agents in the environment, including chemical substances. Interactions between the latter and the skin are often a cause of onset of contact dermatitis (CD), a multifactorial inflammatory complaint triggered by different pathogenic mechanisms and characterized by many different clinical-morphological pictures, as well as a variable evolution.

Among the various forms of eczema (exogenous and endogenous) (Table ), CD is one of the most common clinical pictures and, indeed, one of the diseases most frequently observed in daily dermatological practice. The prevalence of CD in the general population ranges from 1.7% to 6.3% in the short term and from 6.2% to 10.6%, for longer-term disorders (13 years). The incidence of CD in the worker population accounts for 8598% of all occupational skin disorders, which, in turn, occupy the first place among occupational diseases, or may follow immediately after musculoskeletal complaints and/or hearing damage, depending on the type of occupation.

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