Divya Arora - Pharmaceuticals from Microbes: The Bioengineering Perspective

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Volume 26

Environmental Chemistry for a Sustainable World

Series Editors

Eric Lichtfouse

Aix Marseille Univ, CNRS, IRD, INRA, Coll France, CEREGE, Aix en Provence, France

Jan Schwarzbauer

RWTH Aachen University, Aachen, Germany

Didier Robert

European Laboratory for Catalysis and Surface Sciences, Saint-Avold, France

Other Publications by the Editors

Books

Environmental Chemistry

http://www.springer.com/978-3-540-22860-8

Organic Contaminants in Riverine and Groundwater Systems

http://www.springer.com/978-3-540-31169-0

Sustainable Agriculture

Volume 1: http://www.springer.com/978-90-481-2665-1

Volume 2: http://www.springer.com/978-94-007-0393-3

Book series

Environmental Chemistry for a Sustainable World

http://www.springer.com/series/11480

Sustainable Agriculture Reviews

http://www.springer.com/series/8380

Journals

Environmental Chemistry Letters

http://www.springer.com/10311

More information about this series at http://www.springer.com/series/11480

Editors

Divya Arora , Chetan Sharma , Sundeep Jaglan and Eric Lichtfouse

Pharmaceuticals from Microbes The Bioengineering Perspective

Editors

Divya Arora

Indian Institute of Integrative Medicine, CSIR, Jammu, India

Chetan Sharma

Animal Science University, Guru Angad Dev Veterinary, Ludhiana, Punjab, India

Sundeep Jaglan

Indian Institute of Integrative Medicine, CSIR, Jammu, India

Eric Lichtfouse

Aix Marseille University, CNRS, IRD, INRA, Coll France, CEREGE, Aix en Provence, France

ISSN 2213-7114 e-ISSN 2213-7122

Environmental Chemistry for a Sustainable World

ISBN 978-3-030-01880-1 e-ISBN 978-3-030-01881-8

https://doi.org/10.1007/978-3-030-01881-8

Library of Congress Control Number: 2018963747

Springer Nature Switzerland AG 2019

This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.

The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG

The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

The important thing in science is not so much to obtain new facts as to discover new ways of thinking about them

Sir William Bragg, Nobel Prize in Physics

Microbiology has made a huge contribution to the pharmaceutical industry. Indeed, microbes have been used to produce antibiotics , enzymes, polysaccharides, proteins, vitamins and nucleotides. Further, with the advent of new approaches and modern techniques, pharmaceutical industries are looking for innovative solutions, such as bioengineering, to improve the quality of products and enhance productivity. Bioengineering is a discipline that applies engineering principles of design and analysis to biological systems and biomedical technologies. Bioengineering concepts can be applied to the pharmaceuticals as well as to microbes to generate better quality products. This book presents recent advances in microbial technology with emphasis on drug delivery strategies for healthcare products, vaccine delivery, biotransformation and processing of biopharmaceuticals .

The first chapter by Ageitos and Garcia-Fuentes reviews innovative drug delivery strategies for microbial healthcare products (Fig. , Kumar et al. review the preparation methods of polylactide/polylactide-co-glycolide delivery-based particles, their properties as carriers of bioactive molecules and applications of delivery systems based on polymeric particles against microbes.

Fig. 1

Nanocarriers for innovative drug delivery. Blue areas are hydrophilic; yellow areas are hydrophobic. In Chap. by Ageitos and Garcia-Fuentes

Giorgiana discusses drug delivery systems based on pullulan and derivatives and structured function of therapeutic effects of drugs in Chap..

It was our pleasure to interact with all the authors, and we wish to express our gratitude to all the contributors for accepting our invitation. We greatly appreciate their commitment and contribution in shaping the scattered information from diverse fields into their chapters and incorporating the editorial suggestions to produce this venture.

We also extend our thanks to the Springer Nature team for their generous cooperation at every stage of the book production. We hope that the book will serve to update the knowledge and will be helpful to the students, professors, scientists and researchers who have focus on drug discovery. Lastly, we acknowledge God and our family members, who keep motivating and provided all the channels to work in cohesion and coordination right from the conception of the idea to the finalization of the book.

Divya Arora

Chetan Sharma

Sundeep Jaglan

Eric Lichtfouse

Jammu, India Ludhiana, Punjab, India Jammu, India Aix en Provence, CEREGE, France

Contents

Jose Manuel Ageitos and Marcos Garcia-Fuentes

Sudeep Kumar

Robin Kumar , Divya Jha and Amulya K. Panda

Anca Giorgiana Grigoras

Prakash Parajuli , Biplav Shrestha , Jae Kyung Sohng and Ramesh Prasad Pandey

Anu Mehta

Biplav Shrestha , Anaya Raj Pokhrel , Sumangala Darsandhari , Prakash Parajuli , Jae Kyung Sohng and Ramesh Prasad Pandey

Contributors

Jose Manuel Ageitos

Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS) and Department of Pharmacology, Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Santiago de Compostela, Spain

Sumangala Darsandhari

Department of Life Science and Biochemical Engineering, Sun Moon University, Chungnam, Republic of Korea

Marcos Garcia-Fuentes

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