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Hatem A. Azim - Fertility Challenges and Solutions in Women with Cancer

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Hatem A. Azim Fertility Challenges and Solutions in Women with Cancer

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Editors Hatem A Azim Jr Isabelle Demeestere and Fedro A Peccatori - photo 1
Editors
Hatem A. Azim Jr , Isabelle Demeestere and Fedro A. Peccatori
Fertility Challenges and Solutions in Women with Cancer
Editors Hatem A Azim Jr School of Medicine Tecnologico de Monterrey - photo 2
Editors
Hatem A. Azim Jr
School of Medicine, Tecnologico de Monterrey, Monterrey, Mexico
Isabelle Demeestere
CUB-Erasme, Fertility Clinic, Universit Libre de Bruxelles, Brussels, Belgium
Fedro A. Peccatori
Division of Gynecologic Oncology, European Institute of Oncology, Milan, Italy
ISBN 978-3-030-24085-1 e-ISBN 978-3-030-24086-8
https://doi.org/10.1007/978-3-030-24086-8
Springer Nature Switzerland AG 2020
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG

The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

This book addresses a highly controversial and challenging subject, which is related to fertility management of young women with cancer. In light of the improvement in cancer survival and the rising trend of delaying childbearing over the past decade, an increasing number of oncologists and fertility specialists are often faced with young women with cancer inquiring into fertility-related issues in routine clinical practice.

Over the past decade, the field of fertility management of cancer patients has evolved enormously moving from managing patients based on anecdotes and perceptions to counseling based on evidence, thanks to a large amount of clinical and experimental research that has been generated and published by several groups around the globe.

This book gathers worldwide experts who have made important contributions in the field of fertility management of young cancer patients. Several subjects are discussed spanning from understanding the feasibility and safety of pregnancy in cancer survivors to the various fertility preservation methods that could be used, in addition to fertility counseling of special subgroups of patients like those with germline mutations or with endocrine sensitive tumors. The book also addresses controversies related to the role of ovarian tissue cryopreservation and LHRH analogues. We strongly believe that this book will fulfill its aim in providing busy clinicians with a valuable resource in counseling their patients in routine clinical practice.

Hatem A. Azim Jr
Isabelle Demeestere
Fedro A. Peccatori
Monterrey, Mexico Brussels, Belgium Milan, Italy
Contents
Part IOverview on Pregnancy in Cancer Survivors and Fertility Preservation Options
Barbara Buonomo , Hatem A. Azim Jr , Carlo Alviggi and Fedro A. Peccatori
Hatem A. Azim Jr
Marieke van der Zalm , Frederic Amant and Joris van Drongelen
Isabelle Demeestere
Javier Domingo and Antonio Pellicer
Part IIChallenges to Fertility Preservation in Women with Cancer
Joanne Frankel Kelvin
Antonio Di Meglio , Ines Vaz-Luis and Barbara Pistilli
Sukhkamal B. Campbell and Terri L. Woodard
Ghina Ghazeeri and Dalia Khalife
Part IIIControversial Topics in Fertility Counseling of Breast Cancer Patients
Volkan Turan and Kutluk Oktay
Cynthia Villarreal-Garza , Edna A. Lopez-Martinez and Hatem A. Azim Jr
Margherita Condorelli and Matteo Lambertini
About the Editors
Hatem A. Azim Jr MD, PhD

is a medical oncologist and an adjunct professor at the School of Medicine of the Monterrey Institute of Technology and the American University of Beirut. He also serves as faculty for the European Society for Medical Oncology (ESMO) and the European School of Oncology. He holds a masters degree from the University of Newcastle Upon Tyne (UK) and a PhD from the Universit Libre de Bruxelles (Belgium). Dr. Azim has published more than 120 peer-reviewed articles, contributed to 10 books, and been an invited speaker at the major oncology conferences. In recognition to his research in the field of breast cancer in young women and its relation to pregnancy and fertility, Dr. Azim has received the American Society of Clinical Oncology Merit Award, the ESMO Translational Research Award, and the University of Padua Breast Cancer Research Award.

Isabelle Demeestere MD, PhD

is a gynecologist at the fertility clinic in Erasme Hospital (Brussels, Belgium) and the Director of the Research Laboratory on Human Reproduction at the Universit Libre de Bruxelles (ULB). After earning a PhD in fertility preservation for cancer patients, she completed her research training at McGill University, Canada, and became research associate at the FNRS. She was among the earliest innovators in the fertility preservation field and is responsible for the oncofertility unit at Erasme Hospital. She is a member of several scientific societies and author or coauthor of over 60 articles and book chapters in the field.

Fedro Alessandro Peccatori MD, PhD

is a specialist in Medical Oncology and Obstetrics & Gynecology. He acts as Director of the Fertility and Pregnancy Unit at the European Institute of Oncology (IEO) and Scientific Director of the European School of Oncology (ESO) Milan, Italy. Fertility and pregnancy issues in young women with cancer are his main research interests. He has published more than 190 peer-reviewed articles in international journals and has been the editor or author of more than 10 books on cancer and reproduction. He has been invited as speaker for ASCO, ESGO, and ESMO, where he is part of the Adolescent and Young Adults working group.

Part I Overview on Pregnancy in Cancer Survivors and Fertility Preservation Options
Springer Nature Switzerland AG 2020
H. A. Azim Jr et al. (eds.) Fertility Challenges and Solutions in Women with Cancer https://doi.org/10.1007/978-3-030-24086-8_1
1. Epidemiology and General Considerations of Pregnancy Following Cancer Diagnosis
Barbara Buonomo
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