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Library of Congress Cataloging-in-Publication Data
Names: Hartl, Daniel L., author.
Title: Essential genetics and genomics / Daniel L. Hartl.
Other titles: Essential genetics
Description: Seventh edition. | Burlington, MA : Jones & Bartlett Learning,
[2018] | Preceded by Essential genetics / Daniel L. Hartl. 6th ed. 2014. |
Includes bibliographical references and index.
Identifiers: LCCN 2018042898 | ISBN 9781284152456 (pbk.) | ISBN 9781284152685
(e-ISBN)
Subjects: | MESH: Genetic Phenomena | Genomics
Classification: LCC QH430 | NLM QU 500 | DDC 572.8/6dc23
LC record available at https://lccn.loc.gov/2018042898
6048
Printed in the United States of America
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Brief Contents
Contents
the human connection One Gene, One Enzyme
George W. Beadle and Edward L. Tatum (1941)
the human connection Blood Feud
Karl Landsteiner 1901
the human connection Sick of Telomeres
William C. Hahn, Christopher M. Counter, Ante S. Lundberg, Roderick L. Beijersbergen, Mary W. Brooks, and Robert A. Weinberg, 1999
the human connection Starch Contrast
George H. Perry, Nathaniel J. Dominy, Katrina G. Claw, Arthur S. Lee, Heike Fiegler, Richard Redon, John Werner, et al., 2007
the human connection Catch 21
Jerome Lejeune, Marthe Gautier, and Raymond Turpin (1959)
the human connection Sickle-Cell Anemia: The First Molecular Disease
Vernon M. Ingram 1957
the human connection The Sex Life of Bacteria
Joshua Lederberg and Edward L. Tatum (1946)
the human connection Poly-U
Marshall W. Nirenberg and J. Heinrich Matthaei (1961)
the human connection Double Trouble
Andrew Fire, SiQun Xu, Mary K. Montgomery, Steven A. Kostas, Samuel E. Driver, and Craig C. Mello (1998)
the human connection Skeletons in Our Closet
Richard E. Green, Johannes Krause, Adrian W. Briggs, Tomislav Maricic, Udo Stenzel, Martin Kircher, Nick Patterson, and 49 other authors (2010)
the human connection Distinguished Lineages
J. E. Sulston, E. Schierenberg, J. G. White, and J. N. Thomson (1983)
the human connection Damage Beyond Repair
Frederick S. Leach and 34 other investigators (1993)
the human connection Two Hits, Two Errors
Alfred G. Knudson (1971)
the human connection Resistance in the Blood
Anthony C. Allison (1954)
the human connection Pinch of This and a Smidgen of That
Oliver Smithies (2005)
Preface
A good teacher aims to uncover a subject, not cover it. So said a wise former teacher of mine. In revising Essential Genetics and Genomics, Seventh Edition , Ive tried to heed this advice. To un cover a subject means to expose, exhibit, unveil. To help un cover genetics, this new edition is:
Streamlined , with emphasis on concepts illuminated by vivid example and stripped of extraneous detail
Focused , with Learning Objectives stated explicitly at the beginning of each chapter
Skills oriented , with Stop & Think problems inserted at strategic points in the text to enhance the reading experience and encourage higherorder, analytical thinking.
The brevity of the text meets the needs of the shorter, less comprehensive introductory course of one semester or quarter. The choice of topics is intended to help students master the following scientific competencies:
Understand the basic processes of gene transmission, mutation, expression, and regulation.
Analyze genetic processes using numerical relationships including ratios and proportions.
Learn to formulate genetic hypotheses in a statistical framework, work out their consequences, and test the results against observed data.
Develop basic skills in problem solving, including single-concept exercises, those requiring the application of several concepts in logical order, and numerical problems requiring some arithmetic for solution.
Interpret genetic data and make valid inferences to reveal the underlying causes.
Acquire an appreciation of current trends in genetics, as well as the social and historical context in which genetics has developed.