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Salvatore Fanali - Liquid Chromatography

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A single source of authoritative information on all aspects of the practice of modern liquid chromatography suitable for advanced students and professionals working in a laboratory or managerial capacity


  • Chapters written by authoritative and visionary experts in the field provide an overview and focused treatment of a single topic
  • Comprehensive coverage of modern liquid chromatography from theory, to methods, to selected applications
  • Thorough selected references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision making
  • Extensive original tables and figures, placing recent research developments into a general context
  • Worked examples, intuitive explanations, and clear figures reinforce learning
  • Salvatore Fanali: author's other books


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    Liquid Chromatography Fundamentals and Instrumentation Salvatore Fanali Paul R - photo 1
    Liquid Chromatography
    Fundamentals and Instrumentation

    Salvatore Fanali

    Paul R. Haddad

    Colin F. Poole

    Peter Schoenmakers

    David Lloyd

    Table of Contents Copyright Elsevier 225 Wyman Street Waltham MA 02451 USA - photo 2

    Table of Contents
    Copyright

    Elsevier

    225, Wyman Street, Waltham, MA 02451, USA

    The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK

    Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands

    Copyright 2013 Elsevier Inc. All rights reserved.

    No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elseviers Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: , and selecting Obtaining permission to use Elsevier material

    Notice

    No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made

    Library of Congress Cataloging-in-Publication Data

    Application Submitted

    British Library Cataloguing in Publication Data

    A catalogue record for this book is available from the British Library

    ISBN: 978-0-12-415807-8

    For information on all Elsevier publications visit our web site at store.elsevier.com

    Printed and bound in USA

    13 14 15 10 9 8 7 6 5 4 3 2 1

    Contributors Z Aturki Institute of Chemical Methodologies Italian National - photo 3

    Contributors

    Z. Aturki , Institute of Chemical Methodologies, Italian National Council of Research (IMC-CNR), Area della Ricerca di Roma I, Rome, Italy

    N. Bohni , School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Geneva, Switzerland

    A. Cavazzini , Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, Ferrara, Italy

    S. Crotti , DAIS, C Foscari University, Venezia, Italy

    G. DOrazio , Institute of Chemical Methodologies, Italian National Council of Research (IMC-CNR), Area della Ricerca di Roma I, Rome, Italy

    J.W. Dolan , LC Resources, Inc., Walnut Creek, CA, USA

    A.S. Edison , Department of Biochemistry and Molecular Biology and National High Magnetic Field Laboratory, University of Florida, Gainesville, Florida

    S. Fanali , Institute of Chemical Methodologies, Italian National Council of Research (IMC-CNR), Area della Ricerca di Roma I, Rome, Italy

    A. Felinger , Department of Analytical and Environmental Chemistry, University of Pcs, Pcs, Hungary

    F. Foret , Institute of Analytical Chemistry ASCR, Brno, Czech Republic

    T. Fornstedt , Department of Engineering and Chemical Sciences, Karlstad University, Karlstad, Sweden; Analytical Chemistry, Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden

    P. Forssn , Department of Engineering and Chemical Sciences, Karlstad University, Karlstad, Sweden

    M.C. Garca-lvarez-Coque , Department of Analytical Chemistry, University of Valncia, Spain

    I. Isak , CNR-ISTM, Corso Stati Uniti 4, Padova, Italy

    R. Kaliszan , Department of Biopharmaceutics and Pharmacodynamics, Medical University of Gdask and Department of Biopharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toru, Gdask, Poland

    M. Kaspereit , Friedrich-Alexander-Universitt Erlangen-Nrnberg, Lehrstuhl fr Thermische Verfahrenstechnik, Erlangen, Germany

    J. Kuligowski , Department of Analytical Chemistry, University of Valencia, Edificio Jernimo Muoz, Burjassot, Spain

    S. Lamotte , Competence Center Analytics, Ludwigshafen, Germany

    B. Lendl , Institute of Chemical Technologies and Analytics, Vienna University of Technology, Vienna, Austria

    E. Machtejevas , Product Managment Analytical Chemistry, Merck Millipore, Merck KGaA, Darmstadt, Germany

    M. Macka , University of Tasmania, Hobart, Australia

    K. Ndjoko-Ioset , School of Pharmaceutical Sciences, EPGL, University of Geneva, Geneva, Switzerland

    P.N. Nesterenko , ACROSS, University of Tasmania, Hobart, Tasmania, Australia

    B. Paull , ACROSS, University of Tasmania, Hobart, Tasmania, Australia

    J.A. Queiroz , Department of Chemistry, University of Beira Interior, Covilh, Portugal

    G. Quints , Leitat Technological Center, Bio In Vitro Division, Terrassa, Spain

    G. Ramis-Ramos , Department of Analytical Chemistry, University of Valencia, Spain

    A. Rocco , Institute of Chemical Methodologies, Italian National Council of Research (IMC-CNR), Area della Ricerca di Roma I, Rome, Italy

    J. Samuelsson , Department of Engineering and Chemical Sciences, Karlstad University, Karlstad, Sweden

    A. Seidel-Morgenstern , Otto-von-Guericke-Universitt Magdeburg, Institut fr Verfahrenstechnik: Max-Planck-Institut fr Dynamik Komplexer Technischer Systeme, Magdeburg, Germany

    J.G. Shackman , Bristol-Myers Squibb, New Brunswick, NJ

    P. Smejkal , Institute of Analytical Chemistry ASCR, Brno, Czech Republic , University of Tasmania, Hobart, Australia

    L.R. Snyder , LC Resources, Inc., Walnut Creek, CA, USA

    A.M. Striegel , Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD

    C.T. Tomaz , CICS-UBIHealth Sciences Research Centre, University of Beira Interior, Covilh, Portugal

    J.R. Torres-Lapasi , Department of Analytical Chemistry, University of Valncia, Spain

    P. Traldi , CNR-ISTM, Corso Stati Uniti 4, Padova, Italy

    K.K. Unger , Institute of Inorganic Chemistry and Analytical Chemistry, Johannes Gutenberg-University, Duesbergweg, Germany

    J.-L. Wolfender , School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Geneva, Switzerland

    Chapter 1

    Milestones in the Development of Liquid Chromatography

    L.R. Snyder and J.W. Dolan, LC Resources, Inc., Walnut Creek, CA, USA

    Outline

    Introduction

    Developments before 1960

    HPLC at the Beginning

    HPLC Theory and Practice

    New HPLC Modes and Techniques

    Selection of Conditions for the Control of Selectivity

    Columns

    Particles and Column Packing

    Stationary Phases and Selectivity

    Equipment

    Detectors

    Apologies and Acknowledgements

    References

    The importance of liquid chromatography (LC), and especially high-performance LC (HPLC), in todays world hardly needs stating. It is the most widely used technique for the analysis of chemical mixtures and has contributed in a major way to science (especially the biological sciences) and everyday laboratory practice. Liquid chromatography is primarily a practical technique, so our story is limited to those innovations that contributed significantly to its present use in working laboratories. In reflecting on the history of LC, it appears to us that only a few essential actors are in this drama: single individuals whose absence might have delayed the technique by more than a year or two. Thus, the development of present-day LC has largely been an evolutionary, rather than a revolutionary, process. Furthermore, many important innovations within the past 50 years have occurred within industrial research and development (R&D) groups, where it is often not possible to assign credit for a final product to a single person. Finally, every attempt at history suffers from incomplete and conflicting accounts of who did whatand when. In the present history, we try to emphasize what and when rather than who.

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