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Javier Guillen - Laboratory Animals: Regulations and Recommendations for Global Collaborative Research

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Laboratory Animals: Regulations and Recommendations for Global Collaborative Research is the only publication to offer a compilation of standards across the world in the care, welfare and use of animals in research. Timely in the new legislation in numerous regions of the world, this book provides the information in easily accessible, readable language. For professionals across laboratory animal science and biomedical research, Laboratory Animals: Regulations and Recommendations for Global Collaborative Research provides a broad picture of the regulations required in other areas of the world and is essential to appropriately manage animal care and use programs. Offers a worldwide view and global compilation of regulations, guidelines and recommendations for laboratory animal research Saves valuable time researching different regional legislation and regulations Provides insight into factors that play roles in the regulatory framework for countries and geographic regions Written in laymans terms to easily understand legislation and regulations

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Laboratory Animals Regulations and Recommendations for Global Collaborative - photo 1
Laboratory Animals
Regulations and Recommendations for Global Collaborative Research

Edited by

Javier Guilln

Senior Director and Director of European Activities, AAALAC International, Pamplona, Spain

Table of Contents Copyright Academic Press is an imprint of Elsevier 525 B - photo 2

Table of Contents
Copyright

Academic Press is an imprint of Elsevier

525 B Street, Suite 1800, San Diego, CA 92101-4495, USA

32 Jamestown Road, London NW1 7BY, UK

225 Wyman Street, Waltham, MA 02451, USA

Copyright 2014 Elsevier Inc. All rights reserved.

No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher.

Permissions may be sought directly from Elseviers Science & Technology Rights, Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: permissions@elsevier.com. Alternatively, visit the Science and Technology Books website at www.elsevierdirect.com/rights for further information.

Notice

No responsibility is assumed by the publisher for any injury and/or damage to persons, or property as a matter of products liability, negligence or otherwise, or from any use or, operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made.

British Library Cataloguing-in-Publication Data

A catalogue record for this book is available from the British Library

Library of Congress Cataloging-in-Publication Data

A catalog record for this book is available from the Library of Congress

ISBN: 978-0-12-397856-1

For information on all Academic Press publications visit our website at elsevierdirect.com

Typeset by TNQ Books and Journals

www.tnq.co.in

Printed and bound in United States of America

14 15 16 17 18 10 9 8 7 6 5 4 3 2 1

Contributors Juan Manuel Baamonde Centro de Estudios Cientficos CECs - photo 3

Contributors

Juan Manuel Baamonde , Centro de Estudios Cientficos (CECs), Valdivia, Chile

Michael Baar , Canadian Council on Animal Care, Ottawa, ON, Canada

Kathryn Bayne , AAALAC International, Frederick, MD, USA

B. Taylor Bennett , National Association for Biomedical Research, Washington, DC, USA

Ekaterina Akimovna Botovchenco Rivera , Federal University of Goias, Brazil

John F. Bradfield , AAALAC International, Frederick, MD, USA

Cecilia Carbone , Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina

Pradon Chatikavanij , National Research Council of Thailand (NRCT), Bangkok, Thailand

Yvette Chen , The University of Melbourne, Australia

Margaret E. Cooper

Faculty of Veterinary Medicine, University of Nairobi, Kenya

DICE, The University of Kent; and Wildlife Health Services, UK

Anne-Dominique Degryse , Pierre-Fabre, Service de Zootechnie, Institute de Recherche Pierre-Fabre, Castres, France

Idle O. Farah , National Museums of Kenya, Nairobi, Kenya

Yacov Fischer , Israeli Council for Animal Experimentation; and Ministry of Health, Jerusalem, Israel

Montip Gettayacamin , AAALAC International, Samutprakarn, Thailand

Cynthia S. Gillett , University of Minnesota, Minneapolis, MN, USA

Rafael Hernandez Gonzalez , National Institute for Medical Science and Nutrition-SZ, Animal Resources Department, Mexico City, Mexico

Richard Grant , SNBL (Cambodia) Ltd, Khan Daun Penh, Phnom Penh, Cambodia

Gilly Griffin , Canadian Council on Animal Care, Ottawa, ON, Canada

Faisal A. Guhad , Jigjiga Export Slaughter House (JESH) PLC, Somali Regional State, Federal Democratic Republic of Ethiopia

Javier Guilln , AAALAC International, Pamplona, Spain

Alon Harmelin , Department of Veterinary Resources, The Weizmann Institute of Science, Rehovot, Israel

Amanda R. Hau , Faculty of Law, University of Lund, Lund, Sweden

Jann Hau

Faculty of Health and Medical Sciences, University of Copenhagen

Department of Experimental Medicine, University Hospital, Copenhagen, Denmark

Chou-Chu Hong , AAALAC International, New Taipei City, Taiwan

Rony Kalman , Hebrew University, Jerusalem, Israel

Joanna Debby Khoo , Agri-Food and Veterinary Authority of Singapore, Singapore

Tsutomu Miki-Kurosawa , The Institute of Experimental Animal Sciences, Osaka University Medical School, Suita-shi, Osaka, Japan

Abdul Rahim Mutalib , Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, University Putra Malaysia, Serdang, Malaysia

Christian E. Newcomer , Association for Assessment and Accreditation of Laboratory Animal Care International, Frederick, MD, USA

Denise Noonan , The University of Adelaide, SA, Australia

Yasmina Arditi Paramastri , Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA

Jae Hak Park , Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Korea

Peter Penson , Rosanna, Victoria, Australia

Jan-Bas Prins , Leiden University Medical Centre, Leiden, The Netherlands

Syed S.Y.H. Qadri , National Institute of Nutrition (ICMR), Hyderabad, Andhra Pradesh, India

Dondin Sajuthi , Primate Research Center, Veterinary Teaching Hospital, Bogor Agricultural University (IPB), Bogor, Indonesia

John Schofield , J & L Consulting, New Zealand

David Smith , FELASA, Chester, UK

Ouajdi Souilem , Laboratory of Physiology and Pharmacology, National School of Veterinary Medicine, Sidi Thabet, Tunisia

Patri Vergara , International Council for Laboratory Animal Science (ICLAS)

Jason Villano , Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA

Jianfei Wang , GlaxoSmithKline R&D China, Pudong, Shanghai, P.R. China

Imelda Liunanita Winoto , Primate Research Center, Bogor Agricultural University, Bogor, Indonesia

Ehud Ziv , Diabetes Research Unit, Hadassah University Hospital, Jerusalem, Israel

Chapter 1
Same Principles, Some Differences

Javier Guilln, 1AAALAC International , 2International Council for Laboratory Animal Science (ICLAS)

Abstract

The importance of applying the same existing principles in the context of a diverse regulatory framework is highlighted. International organizations can be the best tool to harmonize the implementation of these principles, that represent the common ground for animal research globally.

Keywords

Ethical principles; Animal research; Harmonization

Animals play an essential role in the development of many areas of science. Science, as in many other activities of human life, is being globalized, and the care and use of animals in science is being subjected to this transformation. Globalization of science implies an increase in the level of collaborative research, which may be affected by different cultural and legal requirements. Societal ethical concerns on animal use for scientific purposes have led to the development and implementation of regulatory frameworks in many geographical areas. And even in those areas where specific regulations do not exist, practices in the field are greatly influenced by them. Communication and the spread of science, as well as increasing interinstitutional collaboration and outsourcing, are also important factors.

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