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Sarah A. Vogel - Is It Safe?: BPA and the Struggle to Define the Safety of Chemicals

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We are all just a little bit plastic. Traces of bisphenol A or BPA, a chemical used in plastics production, are widely detected in our bodies and environment. Is this chemical, and its presence in the human body, safe? What is meant by safety? Who defines it, and according to what information? Is It Safe? narrates how the meaning of the safety of industrial chemicals has been historically produced by breakthroughs in environmental health research, which in turn trigger contests among trade associations, lawyers, politicians, and citizen activists to set new regulatory standards. Drawing on archival research and extensive interviews, author Sarah Vogel explores the roots of the contemporary debate over the safety of BPA, and the concerns presented by its estrogen-like effects even at low doses. Ultimately, she contends that science alone cannot resolve the political and economic conflicts at play in the definition of safety. To strike a sustainable balance between the interests of commerce and public health requires recognition that powerful interests will always try to shape the criteria for defining safety, and that the agenda for environmental health research should be protected from capture by any single interest group.

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Is It Safe Is It Safe BPA and the Struggle to Define the Safety of - photo 1
Is It Safe?
Is It Safe?
BPA and the Struggle to Define the Safety of Chemicals
SARAH A. VOGEL

University of California Press one of the most distinguished university - photo 2

University of California Press, one of the most distinguished university presses in the United States, enriches lives around the world by advancing scholarship in the humanities, social sciences, and natural sciences. Its activities are supported by the UC Press Foundation and by philanthropic contributions from individuals and institutions. For more information, visit www.ucpress.edu.

University of California Press

Berkeley and Los Angeles, California

University of California Press, Ltd.

London, England

2013 by The Regents of the University of California

Library of Congress Cataloging-in-Publication Data

Vogel, Sarah A. (Sarah Ann), 1974

Is it safe? : BPA and the struggle to define the safety of chemicals / Sarah A. Vogel.

p. cm.

Includes bibliographical references and index.

ISBN 978-0-520-27357-3 (cloth : alk. paper)ISBN 978-0-520-27358-0 (pbk. : alk. paper)

I. Title.

[DNLM: 1. Phenolstoxicity. 2. Economics. 3. Endocrine Disruptorstoxicity. 4. Environmental Exposurelegislation & jurisprudence. 5. Environmental Exposurestandards. 6. Politics. QV 627]

615.95131dc23 2012026476

Manufactured in the United States of America

20 19 18 17 16 15 14 13

10 9 8 7 6 5 4 3 2 1

In keeping with a commitment to support environmentally responsible and sustainable printing practices, UC Press has printed this book on 50-pound Enterprise, a 30% post-consumer-waste, recycled, deinked fiber that is processed chlorine-free. It is acid-free and meets all ANSI/NISO (z 39.48) requirements.

In memory of my mother, Judy Vogel

Contents
Illustrations
Abbreviations

ACC

American Chemistry Council

AIHC

American Industrial Health Council

APA

Administrative Procedures Act (1946)

APC

American Plastics Council

BPA

bisphenol A

CDC

Centers for Disease Control and Prevention

CERHR

Center for the Evaluation of Risks to Human Reproduction

DES

diethylstilbestrol

ECHA

European Chemicals Agency

EDSTAC

Endocrine Disruptor Screening and Testing Advisory Committee

EFSA

European Food Safety Authority

EPA

U.S. Environmental Protection Agency

FDA

U.S. Food and Drug Administration

FFDCA

Federal Food, Drug and Cosmetic Act (1938, 1958)

FQPA

Food Quality Protection Act (1996)

GAO

General Accounting Office (as of 2004, Government Accountability Office)

GLP

good laboratory practices

GRAS

generally recognized as safe

HEW

Department of Health, Education and Welfare

IARC

International Agency for Research on Cancer

IBT

Industrial Bio-Test

IJC

U.S.-Canadian International Joint Commission

IPCC

Intergovernmental Panel on Climate Change

IRLG

Interagency Regulatory Liaison Group

LOAEL

lowest observed adverse effect level

MCA

Manufacturing Chemists Association

NAS

National Academy of Sciences

NCI

National Cancer Institute

NIEHS

National Institute of Environmental Health Sciences

NIH

National Institutes of Health

NIOSH

National Institute for Occupational Safety and Health

NOAEL

no observable adverse effect level

NRC

National Research Council

NRDC

Natural Resources Defense Council

NTP

National Toxicology Program

OIRA

Office of Information and Regulatory Affairs

OMB

Office of Management and Budget

OSHA

Occupational Safety and Health Administration

OSHAct

Occupational Safety and Health Act

OTA

Congressional Office of Technology Assessment

PBDEs

polybrominated diphenyl ethers

PCBs

polychlorinated biphenyls

PFOA

perfluorooctanoic acid

PVC

polyvinyl chloride

PVP

polyvinylpyrrolidone

REACH

Registration, Evaluation, Authorisation, and Restriction of Chemicals

SDWA

Safe Drinking Water Act (1974, 1996)

SOM

Sensitivity of Method

SPI

Society of the Plastics Industry

TASSC

The Advancement of Sound Science Coalition

TSCA

Toxic Substances Control Act (1976)

WHO

World Health Organization

WWF

World Wildlife Fund, U.S.

Measurements

mg/kg

milligrams per kilogram or parts per million (ppm)

g/kg

micrograms per kilogram (parts per billion; ppb) = 0.001 mg/kg

ng/kg

nanograms per kilogram (parts per trillion; ppt) = 0.000001 mg/kg

Preface

This book asks the question: What makes a chemical safe?

The rapid proliferation of petrochemical compoundsused to make pesticides, plastics, drugs, and many other products of modern lifeover the past sixty years has transformed our global economy and ecology, as well as human understanding of our brave new world. From the mid twentieth century onward, we marched forward in the petrochemical revolution with the assurance that the ease, health, and convenience provided by new pesticides and plastics would outweigh their risks. We were armed with comforting colloquialisms, such as All things in moderation. A bit of chemical exposure could be tolerated, given the enormous benefits petrochemicals afforded society. And indeed, as U.S. chemical production grew, so too did the gross domestic product.

The neat simplicity and seemingly commonsense notion of this logic, however, is being contested today by emerging understandings about the risks of industrial chemicals found within the human body. Recognition that exposure is so ubiquitous that industrial compounds can now be found in umbilical cord blood and amniotic fluid alters our perspective on what defines chemical moderation in the twenty-first century.

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