Fred Saad - Prostate Cancer: Understand the Disease and Its Treatment

PROSTATE

CANCER

PROSTATE

CANCER

Fred Saad, M.D.

Michael McCormack, M.D.

Preface by Armen G. Aprikian, M.D.

Foreword by Dafydd Rhys Williams, M.D., Astronaut

Fourth edition, entirely revised and updated

Cataloguing data available from Bibliothque et Archives nationales du Qubec

1043 Marie-Anne East

Montreal, Quebec

H2J 2B5

514 658 7217

apediteur.com

English revision: Debby Dubrofsky

Book and cover design: Francis Desrosiers in collaboration with Scalpel Design

Cover: Jean-Franois Poliquin

ISBN 978-2-923830-27-8

Legal deposit Bibliothque et Archives nationales du Qubec, 2015

Legal deposit Library and Archives Canada, 2015

Fred Saad, Michael McCormack and Annika Parance Publishing, 2015

All rights reserved.

The publication of this book was made possible through an unrestricted educational grant from sanofi-aventis Canada Inc.

Cataloguing data available from Bibliothque et Archives nationales du Qubec

1043 Marie-Anne East

Montreal, Quebec

H2J 2B5

514 658 7217

apediteur.com

English revision: Debby Dubrofsky

Book and cover design: Francis Desrosiers in collaboration with Scalpel Design

Cover: Jean-Franois Poliquin

ISBN 978-2-923830-27-8

Legal deposit Bibliothque et Archives nationales du Qubec, 2015

Legal deposit Library and Archives Canada, 2015

Fred Saad, Michael McCormack and Annika Parance Publishing, 2015

All rights reserved.

This book is dedicated to my patients, who show me how precious life is and make me feel useful in their fight against prostate cancer. It is also dedicated to my children, Genevive, Julien, Vronique and Simon, and to my wonderful wife Rachel. I am grateful to them for accepting all the time I spend working on prostate cancer.

Dr. Fred Saad

This book is dedicated to men with prostate cancer and their families. It is also dedicated to my children Alie, Sophie and Marie-Hlne, and to my most wonderful wife Marie-Claude. I thank them for their support and encouragement in the pursuit of my academic activities.

Dr. Michael McCormack

The authors would also like to thank their publisher, Annika Parance, whose contributions have greatly improved this fourth edition of their book.

FROM THE SAME PUBLISHER

(apediteur.com)

From the same collection

Fred Saad, M.D. and Michael McCormack, M.D.

Prostate Cancer, 4th edition (2015)

(French version: Le cancer de la prostate)

Pierre Blondeau, M.D. and Paul Harasymowycz, M.D.

Glaucoma (2014)

(French version: Le glaucome)

Fred Saad, M.D. and Michael McCormack, M.D.

Prostate Diseases, 2nd edition (2013)

(French version: Les maladies de la prostate)

Jean Daniel Arbour, M.D. and Pierre Labelle, M.D.

Diabetic Retinopathy (2013)

(French version: La rtinopathie diabtique)

Fadi Massoud, M.D. and Alain Robillard, M.D.

La maladie dAlzheimer (2013)

Jean Daniel Arbour, M.D., Francine Behar-Cohen, M.D.,

Pierre Labelle, M.D. and Florian Sennlaub, M.D.

AMD Age-Related Macular Degeneration (2010)

(French version: DMLA La dgnrescence maculaire lie lge)

WARNING

The content of this book is provided for information purposes only and cannot substitute for a consultation or the personalized advice of a doctor. We recommend that readers speak to a healthcare professional before beginning any treatment.

CONTENTS

CHAPTER 1

CHAPTER 2

CHAPTER 3

CHAPTER 4

CHAPTER 5

CHAPTER 6

CHAPTER 7

PREFACE

Prostate cancer has become the most frequently diagnosed cancer in men today, with one in seven men it in their lifetime.

As a urologic oncologist who treats men with prostate cancer and helps their families deal with the disease, I am often asked for literature to help with the myriad of issues patients face. Although several helpful books are available, this contribution by Dr. Fred Saad and Dr. Michael McCormack is one of the most useful I have come across.

The key to any medical book dealing with a complex topic like prostate cancer is the ability to explain the issues clearly, concisely and comprehensively. I believe the authors of this book have succeeded in providing men and their families with all the information they require to help them through the difficult times during their illness.

Men are often so shaken when they are first told they have prostate cancer that they cannot focus on all the other important information their doctor is telling them. They leave the consultation room feeling terrified, still troubled by a number of questions they wish they had asked. This book can help allay some of their fears and answer many of their questions. More importantly, it can help them prepare the right questions to ask their doctors during subsequent consultations.

This book is very well written, easy to read, and contains a number of detailed illustrations. Most importantly, it provides the latest medical information available, spanning the entire disease spectrum from prevention, diagnosis and treatment to palliative care. The authors provide in-depth information on prevention and the role of diet and nutritional supplements, a comprehensive review of the various successful treatment options (including the emerging area of chemotherapy), and clear explanations of the side effects associated with the various therapies. Moreover, this book is one of the few to devote a considerable amount of space to the significant psychological impact of prostate cancer diagnosis on the individual and his loved ones.

I applaud Dr. Saad and Dr. McCormack for this wonderful book. I am confident it will help numerous men and their families as they cope with prostate cancer. The more men know about prostate cancer, the more they will be able to help themselves and meet the disease head-on.

Armen G. Aprikian, M.D.

Professor of Surgery

Head, Division of Urology, McGill University

Urologist-in-Chief, McGill University Health Centre

FOREWORD

You have prostate cancer. Four words no one ever wants to hear! Yet in Canada, one man in eight risks developing prostate cancer. It is the most frequently diagnosed cancer in men and has increased by 30 percent since 1988. While more commonly diagnosed after age 70, it can also occur in men in their forties and fifties.

Like other forms of cancer, this disease affects not only the patient, but also his spouse and family. At the time of diagnosis there are many questions that need to be answered. Before this book, there was no single publication that provided a simple, concise, practical guide to help patients understand prostate cancer. This volume is an outstanding source of information on the prevention and causes of prostate cancer, early diagnosis, and the treatment options available, as well as their side effects and complications.

Often overlooked areas such as the psychological impact of the disease and the effect of treatment on sexual function and virility are discussed. Readers will become acquainted with the numerous options available to help men preserve their virility, and will feel reassured when they learn that a great number of men continue to lead happy and productive lives for many years even with the disease.