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Patrick C. Walsh - Dr. Patrick Walshs Guide to Surviving Prostate Cancer

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Dr. Patrick Walshs Guide to Surviving Prostate Cancer: summary, description and annotation

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This guide covers every aspect of prostate cancer, from potential causes including diet to tests for diagnosis, curative treatment, and innovative means of controlling advanced stages of cancer.

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This book is not intended as a substitute for medical advice of physicians. The reader should regularly consult a physician in all matters relating to his health, and particularly in respect of any symptoms that may require diagnosis or medical attention.

Copyright 2001, 2007, 2012, 2018 by Patrick C. Walsh and Janet Farrar Worthington

Cover design by Brigid Pearson. Cover copyright 2018 by Hachette Book Group, Inc.

Hachette Book Group supports the right to free expression and the value of copyright. The purpose of copyright is to encourage writers and artists to produce the creative works that enrich our culture.

The scanning, uploading, and distribution of this book without permission is a theft of the authors intellectual property. If you would like permission to use material from the book (other than for review purposes), please contact permissions@hbgusa.com. Thank you for your support of the authors rights.

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First ebook edition: June 2001

Revised ebook edition: May 2018

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ISBN 978-1-538-76363-6

E3-20180418-JV-PC

To all the patients, past and present, who inspired us to write this book, with deep gratitude for the lessons they have taught uswhich we now share with others

This book would not have been possible without the work and experience of many people, too many to name here. We tried, but the result looked like a telephone bookand had about as much personal meaning. So instead of listing all and inevitably missing one or two of the sources upon which weve drawn to produce this guide, we would simply like to thank those colleagues, patients, friends, and family members who have helped us the very most, including:

For this edition, we recruited Edward Schaeffer and Stacy Loeb, international experts in the diagnosis and management of prostate cancer, to take a leading role in formulating the revision. We were also fortunate to have the assistance of these Johns Hopkins experts: Elizabeth Platz in the epidemiology of prostate cancer; Jeffrey Tosoian on Active Surveillance; Phuoc Tran in radiation oncology; Trinity Bivalacqua in the management of erectile dysfunction; and Michael Carducci in medical oncology. In addition, we relied on the discoveries of other Hopkins experts in updating you on the latest in advances in the field: Jonathan Epstein, H. Ballentine Carter, Daniel Song, Theodore DeWeese, Mario Eisenberger, William Nelson, Martin Pomper, Charles Drake, Janet Walczak, Vicki Sinibaldi, Misop Han, Alan Partin, Ashley Ross, Christian Pavlovich, John Isaacs, William Isaacs, William Nelson, Angelo De Marzo, Tamara Lotan, Paula Hurley, Shawn Lupold, Bruce Trock, Jonathan Jarow, Dan Stoianovici, Daniel Chan, Lori Sokoll, Samuel Denmeade, Emmanuel Antonarakis, Jun Luo, Phillip Pierorazio, Edward Wright, and Kenneth Pienta; and on the work of Charles Drake, Robert Brannigan, and Suzanne Conzen.

We also acknowledge with deep gratitude the valuable contributions of these people: Peg Walsh; Alison Currie; Mark, Andy, and Josh Worthington; Blair and Ted Parrack; Bradley and Carole Farrar; Sally Worthington; and Ronald Farrar, at twenty years and counting after his successful radical prostatectomy.

We would like to thank the late Leon Schlossberg, for his original illustrations; David Rini, for his superb ability to tell a story with pictures; Channa Taub, our wonderful literary agent and friend; and Katherine Stopa, our excellent editor.

And as always, we would like to honor Tom Worthington, who died of prostate cancer when he was just beginning to live. Every man this book helps is a victory for you, Tom.

This is our fourth edition of this book, and our sixth book about prostate disease. With every book Patrick Walsh and I have written since 1993, there has been exponentially more hope, and with this edition, there is so much more good newsespecially for those who need it most: men with advanced prostate cancer.

Were not out of the woods yet; men are still dying every day of this heartbreaking disease. In fact, this year, nearly 27,000 American men will die of prostate cancer. If you are an American man, your lifetime risk of getting prostate cancer is 1 in 8. But men who are diagnosed early have an excellent chance of being cured, with minimal side effectsparticularly incontinence and erectile dysfunction (see ); in fact, many men with minimal, very slow-growing cancer can be carefully followed without needing treatment for yearsor maybe ever. Moreover, men who have advanced prostate cancer are living much longersome for decadesand a small but growing number of men who in previous years would have succumbed to widely metastatic cancer are not only alive but feeling great, because of unprecedented advances in hormonal therapy, chemotherapy, immunotherapy and radiopharmaceuticals (radionuclides), and new use of surgery and radiation as treatment for men with limited metastases.

From 1993 to 2014, because of early diagnosisdue to the introduction of PSA testing and a growing awareness that this isnt just an old mans disease, but one that can strike in mid-life, and that prostate cancer screening saves livesand constantly improving treatment, we have seen a 51 percent decline in deaths from prostate cancer. Prostate cancer has dropped from the second to the third most common cause of cancer death, after lung and colorectal cancer, in American men.

Whos at higher risk? We know a lot more about that, too. In startling ) that work particularly well against these particular mutations in breast and ovarian cancer work well in prostate cancer, too.

We know that men of African descent are not only more likely to get prostate cancer, but to have a more aggressive form of the disease. Also sobering: In these men, cancer tends to develop in the part of the prostate that is the most difficult to reach with a needle biopsy. Fortunately, magnetic resonance imaging (MRI) is better than ever, and able to reveal cancer that previously couldnt be detected.

We know that obesity and smoking make it more likely for you to get prostate cancer, and that quitting smoking and losing weight can lower your odds of getting this diseaseor, if you already have it, make it less likely that you will die of it (see ).

We also know, unfortunately, that the U.S. Preventive Services Task Force (USPSTF) did a terrible disservice to all men in 2012 when it recommended against routine screening for prostate cancer for men with no risk factors. One major problem with this decisionmade without the advice of a single urologistis that a lot of men dont know they are at higher risk. They might have an African ancestor, or a family history of prostate or other cancer, and not know itbecause theyve lost touch with their family, or because many men still dont talk about this disease. It is not uncommon for a grown man to find out that his father or grandfather had prostate cancer, got treated for it, and never told the family. What about men who smoke or are overweight, and dont realize that their risk is higher?

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