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Seaman - The greatest experiment ever performed on women: exploding the estrogen myth

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pt. 1. How did all this happen? -- pt. 2. What do we know now?;With the ardent tone of a close friend, Barbara Seaman draws on forty years of journalistic research to expose the menopause industry and shows how estrogen therapy often causes more problems-including breast cancer, heart attack, and stroke-than it cures. The Greatest Experiment Ever Performed on Women tracks the well-intentioned discovery of synthetic estrogen through the unconscionable and misleading promotion of a dangerous drug.

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Table of Contents PRAISE FOR THE GREATEST EXPERIMENT EVER PERFORMED ON WOMEN - photo 1
Table of Contents

PRAISE FOR THE GREATEST EXPERIMENT EVER PERFORMED ON WOMEN
Astounding.
Cleveland Plain Dealer

A splendid history that exposes how menopause was transformed into a medical problem.
Ruth Rosen, San Francisco Chronicle

The authors fundamental belief that women should understand and control their own bodies reminds readers anew why she is a feminist heroine.
Book Magazine

Its food for thought, at an opportune time.
Arizona Republic

A wake-up call to women about unquestioningly accepting doctors orders.
Booklist (starred review)

Reveals more hard truths.
More

Defending her rights, as a patient and as a mother... she is the reporter who alerted the world to the dangers of birth control pills and hormone replacement therapy.
O, The Oprah Magazine

Seaman passionately and convincingly argues that women have been unnecessarily put at risk by doctors treating menopause as disease.
Biology Digest

Seamans bottom line, like her book, deserves attention.
Philadelphia Inquirer
This book is in appreciation of my children Noah Elana Shira And my - photo 2
This book is in appreciation of my children
Noah, Elana, Shira

And my grandchildren
Sophia, Idalia, Liam, and Ezekiel

Theres No Free Lunch, But Theres Free Dessert
ACKNOWLEDGMENTS
PUBLISHING: To Valerie Borchardt, my calm and delightful agent, and to Leigh Haber, my Hyperion editor, a canary-in-the-mine at sensing upcoming topics, a tiger at getting them into print.
To Ben Loehnen, Leigh Habers crackerjack assistant, and Cassie M. Meyer, who preceded him.
To Christine Ragasa, a careful and trustworthy publicist.
HOMEFRONT: To Laura Eldridge, my intern from Barnard College, writer, editor, critic, original thinker, who helped me begin this book and who stayed on after graduation to see it through.
To Agata Rumprecht at SUNY Stony Brook, who sharpened my pencils and practiced her English here as a little girl from Poland, and who grew up into an accomplished researcher and witty writer.
Additional thanks to Maria Tylutka, Lauren Gmitter, Tatiana Rios, Tim Partridge, Elka Krajewska, Edward Stern, and Timothy Walsh, Esq.
NATIONAL INSTITUTES OF HEALTH: To Vivian Pinn, M.D., Office of Research on Womens Health, and Jacques Rossouw, M.D., Womens Health Initiative; to Sylvia Smoller, Ph.D., and all the Principal Investigators, and their staffs, and to the volunteers who laid their bodies on the line. To Loretta Finnegan, M.D., and Ellen Pollack in Dr. Pinns office. To a new era, where treatment choices are based on evidence, and where patients, and doctors, learn to tell a reliable study from smoke and mirrors.
OTHERS AT THE NIH: To C.W. (Bill) Jameson, Ph.D., National Institute of Environmental Health Science; James Lacey, Ph.D., National Cancer Institute; Sherry Sherman, Ph.D., National Institute on Aging.
FDA: To Philip Corfman, M.D. (retired), Suzanne Parisian, M.D. (author of FDA: Inside and Out), Bruce Stadel, M.D., Susan Wood, Ph,D., Lisa Rarick, M.D.
FDA HISTORY OFFICE: Suzanne White Junod, Ph.D., John Swann, Ph.D.
LIBRARY OF CONGRESS: Frederick W. Bauman.
CONGRESS: Hon. Carolyn Maloney of New York, and Minna Elias and Robin Bachman.
U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES: Donna Shalala, Ph.D., Sarah Kovner:
ACADEMIA AND OTHER EXPERT CONSULTANTS AND SOURCES: Jean Jofen, Ph.D. (psychology); Diana Petitti, M.D. (epidemiology); Pat Cody of DES-Action (archivist of early estrogen and cancer studies, and of past and present information on effects of diethylstilbestrol); Elizabeth Siege1 Watkins, Ph.D. (history); Carl Djerassi, Ph.D. (history); Robert Proctor, Ph.D. (history); David Endo (alternative medicine); Adrienne Fugh-Berman, M.D. (alternative medicine); Pat Crawshaw (osteoporosis); Carol Ann Rinzler (breast cancer); Alison Abbott (history); Lila Wallis, M.D. (osteoporosis); Harry K. Genant, M.D. (osteoporosis); John C. LaRosa, M.D. (heart); Naomi Rogers, Ph.D. (history); Charles Debrovner, M.D. (tapering off estrogen); Harriet Presser, Ph.D. (demography); Larry Sasich (pharmacy and pharmacology); Molly Ginty (sea of estrogens); Barron Lerner, M.D. (cancer politics); Ulf Schmidt (history); Donald T. Critchlow (history); Lara Marks, Ph.D. (history); and Sidney Wolfe, M.D.
WOMENS HEALTH RIGHTS: Cynthia Pearson; Judy Norsigian; Amy Allina; Susan Love, M.D.; Mary Ann Napoli; Sheryl Burt Ruzek, Ph.D.; Anne Rochon Ford; Sharon Batt; Belita Cowan; Shere Hite; Phyllis Chesler, Ph.D.; Paula Caplan, Ph.D.; Ann Kasper, Ph.D.; Byllye Avery; Alice Wolfson, Esq.; Oliva Cousins, Ph.D.
EXPERT READERS AND MANUSCRIPT REVIEW: Myra Apple-ton; Urs Bamert (German translations); Jennifer Baumgardner (history); Jessica Baumgardner; Devra Lee Davis, Ph.D. (sea of estrogens); Michael Patrick Hearn (history); Fredi Kronenberg, Ph.D. (alternative treatments); Kathryn Scarbrough, Ph.D. (Alzheimers); Noah Seaman; Ann OShea (sea of estrogens); Andrea Tone, Ph.D. (history); Betsy Wade.
CORPORATE HISTORIES: Joe Ciccone, Corporate Archivist, Merck & Co; Kim Schillace, Berlex Labs; Christine Berghausen, Andre Schmolke, Wolfgang Frobenious, Schering; Stephen Simes, Biosante and Searle; Lois A. Gaeta, Ayerst Laboratories.
AMERICAN MEDICAL ASSOCIATION: Drummond Rennie, M.D.; Roy Schwarz, M.D. (retired); Harriet Meyer, M.D.; Ron Davis, M.D.
INDEPENDENT MEDICAL SOURCES: No Free Lunch listserve, Biojest Listserve, National Womens Health Network, Health Research Group.
DR. ROBERT GREENBLATT: Edward Greenblatt, Esq.; Deborah Greenblatt; Virendra B. Mahesh, Ph.D.; Paul McDonough, M.D.
DR. ROBERT WILSON: Ronald Wilson.
MADELINE GRAY: Roger Kahn, Sylvia Seaman.
PROVIDERS OF INFORMATION, DOCUMENTS, INTRODUCTIONS, AND OTHER SUPPORT: Nikki Scheuer; Sheila Bandman and Donald Bandman: Judith Rossner and Stanley Leff; Myrna and Jeffrey Blyth; Audrey Flack and Bob Marcus; Maria and Norman Marcus; Judge Emily Jane Goodman; Daniel Simon; Shere Hite; Alix Kates Shulman; Letty Cottin Pogrebin; Jacqui Ceballos; Marlene Sanders; Mary Jean Tully; William Klein; Deborah Chase; Lucy Komisar; Grace Petti; Ernest, Jeri, and Jense Drucker; Elaine, Pablo, and Henry Rosner-Jeria; Ruth Gruber; and Joanna Perlman for her Over the Rainbow work on the Appendix.
HADASSAH MAGAZINE: Joan Michel, Alan Tigay, Zelda Shluker, and the readers who write in.
MS. MAGAZINE: Gloria Steinem
NEW YORK TIMES AND WASHINGTON POST: Alex Ward
PROJECT CENSORED: Peter Phillips
EXTRA: Jim Naureckas

IN MEMORIAM:
TWO SAINTS
Mary Howell, M.D. (d. 1998), and Helen Rodriguez-Trias, M.D. (d. 2001), my dear colleagues who worked tirelessly for the rights of patients, of minorities, of women in medicine, and, being pediatricians, for all children everywhere. Howell was a cofounder of the National Womens Health Network. Rodriguez-Trias was a longtime president of the Board: The womens movement is about survival, about finding our strength and using it to help other women. We reach out to each other to build a different kind of societyone where women are equal in power to men and where children are truly prized.
Dr. Helen Rodriguez-Trias in The Conversation Begins, by Christina Loper Baker and Christina Baker Kline.
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