Lisa M. Sullivan - Essentials of Biostatistics in Public Health

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Library of Congress Cataloging-in-Publication Data
Names: Sullivan, Lisa M. (Lisa Marie), 1961-author.
Title: Essentials of biostatistics in public health / Lisa Sullivan.
Description: Third edition. | Burlington, Massachusetts : Jones & Bartlett
Learning, [2018] | Includes bibliographical references and index.
Identifiers: LCCN 2016048158 | ISBN 9781284108194
Subjects: | MESH: Biostatisticsmethods | Biometrymethods | Public
Healthmethods
Classification: LCC RA409 | NLM WA 950 | DDC 610.72dc23
LC record available at https://lccn.loc.gov/2016048158

6048

Printed in the United States of America
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I am very grateful to Dr. Richard Riegelman for his unending energy and enthusiasm for this project. I thank my family for their encouragement; Casey, Ryan, Aislinn, Abbi, and Gavin for their inspiration; most especially, Kimberly Dukes and Kevin Green for their unending love and support.

This textbook is dedicated to the memory of my cousin Catherine Render. Catherine was a remarkable woman. She was a loving daughter, sister, wife, mother, cousin, and friend who excelled in every role. She lost a long battle with breast cancer in January 2006. She fought through many setbacks, always pushing forward optimistically, taking care of everyone around her, never asking why. She was and always will be an inspiration to me and to so many others who were fortunate enough to know her.

Biostatisticians play an extremely important role in addressing important medical and public health problems. Unfortunately, there are many more problems than solutions. We must never lose sight of the fact that our work is important in improving health and well-being. We need qualified biostatisticians to work in research teams to address problems like breast cancer, cardiovascular disease, diabetes, and so many others.

Essentials of Biostatistics in Public Health, Third Edition provides a fundamental and engaging background for students learning to apply and appropriately interpret biostatistical applications in the field of public health. The examples are real, important, and represent timely public health problems. The author aims to make the material relevant, practical, and engaging for students. Throughout the textbook, the author uses data from the Framingham Heart Study and from observational studies and clinical trials in a variety of major areas. The author presents example applications involving important risk factorssuch as blood pressure, cholesterol, smoking, and diabetes and their relationships to incident cardiovascular and cerebrovascular diseasethroughout. Clinical trials investigating new drugs to lower cholesterol, to reduce pain, and to promote healing following surgery are also considered. The author presents examples with relatively few subjects to illustrate computations while minimizing the actual computation time, as a particular focus is mastery of by-hand computations. All of the techniques are then applied to and illustrated on real data from the Framingham Heart Study and large observational studies and clinical trials. For each topic, the author discusses methodologyincluding assumptions, statistical computations, and the appropriate interpretation of results. Key formulas are summarized at the end of each chapter.