P. D. Mangan - Dumping Iron- How to Ditch This Secret killer and reclaim your life
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Dumping Iron
by
P. D. Mangan
Phalanx Press
Disclaimer: This book contains general information about medical conditions and treatments. The information is not advice, and should not be treated as such. The medical information in this book is provided as is without any representations or warranties, express or implied. The author makes no representations or warranties in relation to the medical information in this book. The author does not warrant that the medical information in this book is complete, true, accurate, up-to-date, or non-misleading. You must not rely on the information in this book as an alternative to medical advice from your doctor or other professional healthcare provider.
If you have any specific questions about any medical matter you should consult your doctor or other professional healthcare provider. If you think you may be suffering from any medical condition, you should seek immediate medical attention. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of information in this book.
Copyright 2016 by P. D. Mangan
Table of Contents
What the Experts Say About Dumping Iron
Dumping Iron by P. D. Mangan is a must read by anybody interested in maintaining optimal health, including those in the medical field. Iron overload is an exceedingly common malady in the population and it is easily diagnosed, but it is under-addressed. It leads to heart disease, diabetes, cancer and numerous other chronic and debilitating illnesses. The good news is that iron excess can be prevented and readily treated, which results in a decreased risk of many diseases and improvement in overall health and vitality. Dumping Iron clearly tells us how to achieve these goals.
Luca Mascitelli, M.D., Lieutenant Colonel, Italian Army, and author of numerous scientific papers on iron and health.
In Dumping Iron , Dennis Mangan has provided the reader access to a massive scientific data pool linking body iron overload to major diseases of mankind I submit that Dumping Iron should be required reading in science and nutrition for high school and above. The ultimate triumph of Dumping Iron might be an informed public that will increasingly access ferritin test screening, and health care providers better prepared to interpret tests of iron status, particularly the ferritin level. Acknowledgment of risks of iron overload and proper product labeling might lead to reduced public iron intoxication and improved population health to a degree that would be no less than monumental!
Leo Zacharski, M.D., Professor of Medicine, Geisel School of Medicine, Dartmouth College
Dennis Mangans revolutionary new book Dumping Iron: How to Ditch This Secret Killer and Reclaim Your Health is a must read even for the most informed Health and Fitness professional.
For those of us writing in the medical/anti-aging field, it is imperative to cite your work, as much of the research is newly available and stands directly in the face of modern medical advice. Denniss work is authoritative and his writing style is clear and thought provoking. In fact, I dont believe there has been a written book on the risks of elevated iron levels so extensively researched- offering the reader more than 120 citations.
His thesis that excess iron accumulates in the blood as one ages leading to cellular and biological inflammation and ultimately the diseases of aging (heart disease, cancer, and cognitive decline), is impossible to dispute. So much so, Im going to share it with my inner circle and implore them to get their ferritin levels tested.
Do yourself a favor and read this book immediately. The overall success of your aging process and the extension of your life may depend on it.
Jay Campbell, author of The Definitive Testosterone Replacement Therapy MANual
By E. D. Weinberg, PhD
Iron has been compared to fire. A small amount of fire is quite useful in our stoves and furnaces. But when fire is ravaging the contents and walls of our homes BEWARE. In this informative book, Dennis Mangan makes clear the devastation that can be caused by excessive/misplaced iron in the tissues and walls of our bodies. We learn that for essentially all diseases infections, cancers, Alzheimers, Parkinsons, diabetes, gout, osteoporosis, cardiovascular ills, and more that the iron burden is a dangerous risk factor.
But equally important, the author describes a variety of well tested methods that are readily available to neutralize the iron peril. Adoption of even a few of these methods can remarkably decrease iron-catalyzed disease episodes, enhance well-being, and, not least, increase longevity.
During the past sixty years, the many hundreds of published studies of iron toxicity have consistently demonstrated the hazard of ignoring the dangerous metal. An early report summarized it well: The iron heart is not a strong heart; it is a very weak one.
E.D. Weinberg is Professor Emeritus of Biology at Indiana University, and the author of over 140 scientific papers, many of them on the role of iron in disease.
By Leo Zacharski, M.D.
In Dumping Iron, Dennis Mangan has provided the reader access to a massive scientific data pool linking body iron overload to major diseases of mankind.
Iron, in excess of requirements for normal respiration, generates highly toxic hydroxyl radicals contributory to inflammation and oxidative stress responsible for the grand global health challenges: diabetes, cancer, neurodegenerative disorders, hypertension and cardiovascular disease. Among well-documented health hazards, iron excess must remain one of the worlds best kept secrets.
Using masterful prose, Mangan has outlined the magnitude of the problem and described factors responsible for iron blindness among health care providers and within the general public. This volume can claim status as an iron nutrition owners manual.
The degree to which iron is noxious is determined by the dose times the duration: the more iron on-board and the longer it remains, the greater the risk. Normal iron levels represented by ferritin are those levels associated with minimum disease risk and maximum longevity.
Several epidemiological studies have shown increased longevity associated with ferritin below an upper threshold of about 80 to 90 ng/ml, the plateau in post-menopausal women (shown in the first figure in this book) that is also conducive to older age in men those with higher levels have dropped out of the population by dying. Plots of paired values for the ferritin and hemoglobin obtained from a large clinical trial of iron reduction showed that rising ferritin levels up to about 80 ng/ml are associated with rising hemoglobin levels within the normal range, indicating use of iron for red cell oxygen transport. Above the 80 ng/ml cut-off, ferritin levels continue to rise but without physiologic correspondence.
Ferritin levels are a continuum and susceptibility to iron toxicity thus may commence at ferritin levels mistakenly considered to be within the reference range used commonly. This explains why much higher ferritin levels are more clearly disease-associated while levels in the 100 to 150 ng/ml range mysteriously appear in some, but not all, studies as disease-associated.
The tragedy of ferrotoxic disease is compounded by unnecessary ingestion of highly absorbable iron supplements by an unwary public, for a disease that most people do not have (iron deficiency), and without their knowledge or consent. Recommendations for minimum daily requirements for iron used to justify supplementation are based on estimates applied blindly to a population without consideration of existing body iron levels.
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