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Juan P. Palazzo MD - Practical Surgical Pathology of the Breast

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Juan P. Palazzo MD Practical Surgical Pathology of the Breast
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Practical Surgical Pathology of the Breast: summary, description and annotation

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Practical Surgical Pathology of the Breast is a comprehensive and accessible guide for the practicing pathologist and trainee. It provides anatomic pathologists with the essential knowledge and tools to navigate breast cases and classification systems that are commonly and uncommonly found in everyday practice. Particularly challenging topics such as understanding the molecular mechanisms linked to breast cancer and the interpretation of molecular tests, are covered in clear prose, along with useful discussions on diagnostic challenges written by world experts. The use of immunohistochemistry in breast pathology is discussed in detail and how to apply it to resolve diagnostic problems. As a result, the book simplifies difficult-to-master issues such as recognizing therapy-induced changes to breast specimens and identifying borderline breast lesions and many more.

Each chapter features high-quality images and stains, tables that emphasize differential diagnoses, text that highlight common diagnostic pitfalls with corresponding tips, as well as helpful key points and how to reach an accurate diagnosis using appropriate procedures and tests. With Practical Surgical Pathology of the Breast as a guide, practitioners and residents can hone their diagnostic skills, resolve difficult cases and improve their approach to breast cases in their daily practice.

Key Features:

  • Written by world-renowned breast pathology experts
  • Emphasizes the differential diagnosis problem-solving process found in everyday practice
  • Contains over 700 high-quality images including numerous immunohistochemical stains which are essential when comparing breast entities
  • Includes detailed coverage of core biopsy interpretation, precursors of mammary carcinoma and their mimics, papillary lesions, flat epithelial atypia, adenosis, microinvasive carcinoma, carcinomas with good prognosis, mesenchymal lesions, triple negative carcinomas, lymphomas of the breast, and interpretation of therapy-related changes
  • Highlights diagnostic pitfalls and common problems that a pathologist will encounter and includes practical tips throughout to guide the proper interpretation of breast lesions and the proper application of tests to reach accurate diagnoses

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Contents

Guide
i Practical Surgical Pathology of the Breast ii iii Practical Surgical - photo 1

i Practical Surgical Pathology of the Breast ii

iii Practical Surgical Pathology of the Breast

Editor

Juan P. Palazzo, MD

Professor of Pathology

Department of Pathology,

Cell Biology, and Anatomy

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

iv Visit our website at wwwspringerpubcom ISBN 9781620701058 ebook ISBN - photo 2

iv Visit our website at www.springerpub.com

ISBN: 9781620701058

ebook ISBN: 9781617052835

Acquisitions Editor: David DAddona

Compositor: diacriTech, Chennai

Copyright 2018 Springer Publishing Company.

Demos Medical Publishing is an imprint of Springer Publishing Company, LLC.

All rights reserved. This book is protected by copyright. No part of it may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher.

Medicine is an ever-changing science. Research and clinical experience are continually expanding our knowledge, in particular our understanding of proper treatment and drug therapy. The authors, editors, and publisher have made every effort to ensure that all information in this book is in accordance with the state of knowledge at the time of production of the book. Nevertheless, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the contents of the publication. Every reader should examine carefully the package inserts accompanying each drug and should carefully check whether the dosage schedules mentioned therein or the contraindications stated by the manufacturer differ from the statements made in this book. Such examination is particularly important with drugs that are either rarely used or have been newly released on the market.

Library of Congress Cataloging-in-Publication Data

Names: Palazzo, Juan P., editor.

Title: Practical surgical pathology of the breast / [edited by] Juan P. Palazzo.

Description: New York : Springer Publishing Company, [2018] | Includes bibliographical references.

Identifiers: LCCN 2017056810| ISBN 9781620701058 | ISBN 9781617052835 (ebook)

Subjects: | MESH: Breastpathology | Breast Diseasesdiagnosis | Breastsurgery

Classification: LCC RG491 | NLM WP 815 | DDC 618.1/9dc23 LC record available at https://lccn.loc.gov/2017056810


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Printed in the United States of America.

18 19 20 21 22 / 5 4 3 2 1

v To My Parents, Laura and Domingo vi

vii CONTENTS

Aylin Simsir and Joan F. Cangiarella

Edi Brogi, Camilla Cristando, and Hannah Y. Wen

Cansu Karakas, Erika Resetkova, and Aysegul A. Sahin

Juan P. Palazzo, Beln Prez Mies, Esteban Gnass, and Jose Palacios Calvo

Melinda F. Lerwill

Upasana Joneja and Juan P. Palazzo

Dilip D. Giri

Andrew P. Sciallis and Celina G. Kleer

Melinda E. Sanders and Jean F. Simpson

Melinda E. Sanders, Gaetano Magro, and Juan P. Palazzo

Judith A. Ferry

Elena Brachtel

Felipe C. Geyer, Fresia Pareja, Magali Lacroix-Triki, and Jorge S. Reis-Filho

Felipe C. Geyer, Caterina Marchi, and Jorge S. Reis-Filho

viii

ix CONTRIBUTORS

Elena Brachtel, MD

Associate Professor of Pathology

Harvard Medical School;

Assistant Pathologist

Department of Pathology

Massachusetts General Hospital

Boston, Massachusetts

Edi Brogi, MD, PhD

Director of Breast Pathology

Attending PathologistDepartment of Pathology

Memorial Sloan Kettering Cancer Center;

Professor of Pathology and Laboratory Medicine

Weill Cornell Medical College

New York, New York

Jose Palacios Calvo, MD

Head of Anatomical Pathology Service

Ramn y Cajal University Hospital

IRYCIS, Alcal University and CIBERONC

Madrid, Spain

Joan F. Cangiarella, MD

Vice Chair of Clinical Operations, Department of Pathology

Associate Professor of Pathology

New York University School of Medicine

New York, New York

Camilla Cristando, MD

Breast Pathology Fellow

Department of Pathology

Memorial Sloan Kettering Cancer Center

New York, New York

Judith A. Ferry, MD

Pathologist

Director of Hematopathology

The James Homer Wright Pathology Laboratories of the Massachusetts General Hospital

Boston, Massachusetts

Felipe C. Geyer, MD

Pathologist

Senior Research Scientist

Department of Pathology

Memorial Sloan Kettering Cancer Center

New York, New York

Dilip D. Giri, MD

Pathologist

Department of Pathology

Memorial Sloan Kettering Cancer Center

New York, New York

Esteban Gnass, MD

Department of Pathology, Cell Biology, and Anatomy

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

Upasana Joneja, MD

Department of Pathology, Cell Biology, and Anatomy

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

Cansu Karakas, MD

Instructor

Department of Experimental Radiation Oncology

The University of Texas MD Anderson Cancer Center

Houston, Texas

Celina G. Kleer, MD

Harold A. Oberman Collegiate Professor of Pathology, Breast Pathology

Director, Breast Pathology Program

Anatomic Pathology

Department of Pathology

University of Michigan

Ann Arbor, Michigan

x Magali Lacroix-Triki, MD, PhD

Pathologist

Dpartement de Biologie et Pathologie Mdicales

Gustave-Roussy Cancer Campus

Villejuif, France

Melinda F. Lerwill, MD

Associate Pathologist

Department of Pathology

Massachusetts General Hospital

Boston, Massachusetts

Gaetano Magro, MD, PhD

Department of Medical and Surgical Sciences and Advanced Technologies

G.F. Ingrassia

Azienda Ospedaliero-Universitaria Policlinico-Vittorio Emanuele

Anatomic Pathology Section

School of Medicine

University of Catania

Catania, Italy

Caterina Marchi, MD, PhD

Pathologist

Department of Medical Sciences

University of Turin

Torino, Italy

Beln Prez Mies, MD

Professor

Anatomical Pathology Service

Ramn y Cajal University Hospital.

IRYCIS, Alcal University and CIBERONC

Madrid, Spain

Juan P. Palazzo, MD

Professor of Pathology

Department of Pathology, Cell Biology, and Anatomy

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania

Fresia Pareja, MD, PhD

Breast Pathology Instructor

Department of Pathology

Memorial Sloan Kettering Cancer Center

New York, New York

Jorge S. Reis-Filho, MD, PhD, FRCPath

Chief, Experimental Pathology Service

Department of Pathology

Memorial Sloan Kettering Cancer Center

New York, New York

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