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Timothy L. Lash - Modern Epidemiology

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Now in a fully revised Fourth Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field. This edition continues to provide comprehensive coverage of the principles and methods for the design, analysis, and interpretation of epidemiologic research. Featuring a new format allowing space for margin notes, this edition
Reflects both the conceptual development of this evolving science and the increasing role that epidemiology plays in improving public health and medicine.
Features new coverage of methods such as agent-based modeling, quasi-experimental designs, mediation analysis, and causal modeling.
Updates coverage of methods such as concepts of interaction, bias analysis, and time-varying designs and analysis.
Continues to cover the full breadth of epidemiologic methods and concepts, including epidemiologic measures of occurrence and effect, study designs, validity, precision, statistical interference, field methods, surveillance, ecologic designs, and use of secondary data sources.
Includes data analysis topics such as Bayesian analysis, probabilistic bias analysis, time-to-event analysis, and an extensive overview of modern regression methods including logistic and survival regression, splines, longitudinal and cluster-correlated/hierarchical data analysis, propensity scores and other scoring methods, and marginal structural models.
Summarizes the history, specialized aspects, and future directions of topical areas, including among others social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, psychiatric epidemiology, injury and violence epidemiology, and pharmacoepidemiology.

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Table of Contents
Modern Epidemiology FOURTH EDITION Timothy L Lash O Wayne Rollins - photo 1
Modern Epidemiology
FOURTH EDITION
Timothy L. Lash
O. Wayne Rollins Distinguished Professor of Epidemiology and Chair
Department of Epidemiology
Rollins School of Public Health, Emory University
Atlanta, Georgia
Tyler J. VanderWeele
John L. Loeb and Frances Lehman Loeb Professor of Epidemiology
Departments of Epidemiology and Biostatistics
Harvard T.H. Chan School of Public Health
Boston, Massachusetts
Sebastien Haneuse
Professor of Biostatistics
Department of Biostatistics
Harvard T. H. Chan School of Public Health
Boston, Massachusetts
Kenneth J. Rothman
Distinguished Fellow, Research Triangle Institute
Research Triangle Park, North Carolina
and
Professor of Epidemiology
Boston University School of Public Health
Boston, Massachusetts
Index Note Page numbers followed by f indicate figures t indicate tables - photo 2
Index
Note : Page numbers followed by f indicate figures, t indicate tables, and b indicate boxes.
A
Absence of effect, evidence of, f
Absolute effect,
Absolute measures,
Absolute rate,
Absolute test statistics, P- values, . See also P-values
Abstracts
data capture,
form,
Accelerated failure time (AFT) model, .
Acceptability of surveillance systems,
Accuracy. See also Bias; Measurement error; Misclassification; Precision; Validity
of data,
of diagnostic test,
of estimation,
generalizability,
matching, t
of measurement/classification,
of models,
of prediction,
random error,
of recall,
smoothing,
of statistical approximations,
study design,
systematic error,
test statistics,
Acquired immune deficiency syndrome (AIDS),
surveillance,
Active comparator,
Active surveillance,
Acyclic graphs. See Causal diagrams; Directed acyclic graphs (DAGs)
Adaptive randomization, clinical trials,
Additive hazards models,
Additive interaction,
for continuous outcomes,
regression models
confounding factors,
log-linear model,
vs. multiplicative interaction,
public health implications,
resampling-based approach,
standard errors,
Adherence, in clinical trials,
Adjacent-category logistic model,
Adjusted hazard ratio,
Adjusted odds ratios, unadjusted odds ratios,
Adjustment, . See also Confounding; Confounders; Mantel-Haenszel methods; Regression analysis; Standardization
Administrative censoring,
Administrative databases,
Adverse Event Reporting System (AERS),
Adverse events, studying,
AFT. See Accelerated failure time (AFT) model
Age at event. See Average age, at event
Age groups,
Agent-based modeling (ABMs)
agent-agent interaction matrix,
behavioral change theories, f
calibration,
characteristics,
adaptivity,
emergence, f
stochasticity, f
empirical methods,
epidemiological applications,
health behavior,
infectious disease transmission,
interference,
interpretation,
microscale computational models,
microsimulation approach,
model construction,
model development process,
Monte Carlo simulation,
parameterization,
rationale for,
rules,
Schelling segregation model,
verification and validation,
Age-period-cohort analysis, exploratory mixed design study,
Aggregate measures, ecologic studies,
AIC. See Akaike information criterion (AIC)
AIDS. See Acquired immune deficiency syndrome (AIDS)
Akaike information criterion (AIC),
Algorithmic selection strategies,
Alpha level,
ALS. See Amyotrophic lateral sclerosis (ALS)
Alternative hypothesis,
Alzheimer disease,
Amyotrophic lateral sclerosis (ALS),
Analogy, causal inference,
Analysis. See also specific entries
ecologic,
methods, classification of,
multiple outcomes,
Analytic studies, hypothesis generation,
Analytic validity, of biomarker,
Anomalies,
Anatomical Therapeutic Chemical (ATC) Classification System,
Antagonism, . See also Biologic interaction
Anthropometry, measures of body composition,
Antibiotic, in animals, surveillance,
Apportionment ratios, study efficiency,
Approximate statistics
accuracy of,
Bayesian,
likelihood-ratio method,
score method,
Wald method,
Area under the curve (AUC),
ARIMA models. See Autoregressive integrated moving average (ARIMA) models
Association, . See also Measures of association; Regression
biased,
in causal diagrams and,
causal structures and,
causation,
confounding and,
standardized measures,
unbiased,
validity of,
Associational ratio, confounding,
Association studies
analyzing associations,
family-based association studies,
genetic markers imputation,
genome-wide association study (GWAS),
next-generation sequencing,
population stratification,
statistical testing,
unrelated individuals,
Asymptotic methods. See Large-sample methods
Atkinson index, segregation,
Attack rate,
Attention-deficit hyperactivity disorder (ADHD),
Attributable fractions, . See also Preventable fractions
causation,
estimation,
etiologic fractions, f
excess fractions,
susceptibility,
terminology,
Attributable proportion, . See also Attributable fractions
Attributable risk, . See also Attributable fractions
Audit studies,
Autism spectrum disorder (ASD),
Auxiliary hypotheses,
Autoregressive integrated moving average (ARIMA) models,
Average age
at death,
at event,
Average exposure assignment schema,
Average exposure measures,
Average incidence time, survival proportion,
Average intensity, and alternatives,
Average risk,
case-cohort studies,
effects on incidence rates,
Average survival time, estimation of,
B
Back-door paths,
Bacterial infections,
Bacterial pathogens, laboratory-based surveillance,
Balancing scores,
exposure scores,
outcome scores,
Bariatric surgery intervention,
Barker hypothesis,
Baseline hazard,
Base priors, sensitivity analyses,
Baseline values, bias,
Basic reproductive number, state of infectiousness,
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