International Atomic Energy Agency - Atlas of Non-FDG PET–CT in Diagnostic Oncology

Positron emission tomograph yc omputed tomography (PE TC T) plays a central role in the management of cancer patients and is an increasingly important part of the overall health care landscape owing to the rising prevalence of non-communicable diseases, the need for early and accurate diagnostic methods, technological developments both in hardware and in software, the availability of new tracers and the acceptance of this technology in eme rging markets.

Fluorodeoxyglucose (FDG) PE TC T has earned global recognition as a significant tool in the modern management of cancer patients and is rapidly becoming an important imaging modality for patients with cardiac, neurological and infectiou s/i nflammatory conditions. Despite its proven benefits as a PET radiopharmaceutical in oncology, FDG has limitations in the assessment of several relevant tumours such as prostate cancer. In addition, new therapeutic options available today in the management of cancer have underscored the need for assessing tumour characteristics other than metabolism. Therefore, there has been a pressing need for the development and clinical assessment of additional PET radiopharmaceuticals that can enable imaging and precise characterization of various aspects of a wide range of mal ignant tumours.

It is hoped that this publication will be beneficial to medical professionals from IAEA Member States for learning and teaching. The IAEA wishes to thank the contributors to the drafting and review of the publication for contributing their knowledge, time and effort. The IAEA officers responsible for this publication were R. Nuez Miller, F. Giammarile and D. Paez of the Division of Human Health.

EDITORIAL NOTE

Although great care has been taken to maintain the accuracy of information contained in this publication, neither the IAEA nor its Member States assume any responsibility for consequences which may arise from its use.

This publication does not address questions of responsibility, legal or otherwise, for acts or omissions on the part of any person.

Guidance provided here, describing good practices, represents expert opinion but does not constitute recommendations made on the basis of a consensus of Member States.

The use of particular designations of countries or territories does not imply any judgement by the publisher, the IAEA, as to the legal status of such countries or territories, of their authorities and institutions or of the delimitation of their boundaries.

The mention of names of specific companies or products (whether or not indicated as registered) does not imply any intention to infringe proprietary rights, nor should it be construed as an endorsement or recommendation on the part of the IAEA.

The IAEA has no responsibility for the persistence or accuracy of URLs for external or third party Internet web sites referred to in this book and does not guarantee that any content on such web sites is, or will remain, accurate or appropriate.

The authoritative version of this publication is the hard copy issued at the same time and available as pdf on www.iaea.or g/p ublications . To create this version for e-readers, certain changes have been made, including a the movement of some figu res and tables.