Anderson's Pediatric Cardiology
FOURTH EDITION
Editor-in-Chief
Gil Wernovsky, MD, FAAP, FACC
Senior Consultant in Pediatric Cardiac Critical Care and Pediatric Cardiology
Children's National Medical Center;
Professor of Pediatrics
George Washington University School of Medicine & Health Sciences
Washington, DC
Associate Editors
Robert H. Anderson, BSc, MD, PhD (Hon), FRCPath, FRCS Ed (Hon)
Professor
Institute of Genetic Medicine
Newcastle University
Newcastle-upon-Tyne, United Kingdom
Krishna Kumar, MD, DM
Professor and Head
Pediatric Cardiology
Amrita Institute of Medical Sciences
Amrita Vishwa Vidyapeetham
Cochin, Kerala, India
Kathleen Mussatto, PhD, RN
Nurse Scientist
Herma Heart Institute
Children's Hospital of Wisconsin;
Associate Adjunct Professor of Cardiothoracic Surgery
Medical College of Wisconsin
Milwaukee, Wisconsin
Andrew N. Redington, MD
Chief of Cardiology
Heart Institute
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio
James S. Tweddell, MD
Chair of Cardiothoracic Surgery
Department of Surgery
Cincinnati Children's Hospital Medical Center;
Professor of Surgery and Pediatrics
University of Cincinnati
Cincinnati, Ohio
Video Editor
Justin T. Tretter, MD
Assistant Professor of Pediatrics
The Heart Institute
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio
Table of Contents
Copyright
Elsevier
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Philadelphia, PA 19103-2899
ANDERSON'S PEDIATRIC CARDIOLOGY, FOURTH EDITION
ISBN: 978-0-7020-7608-4
Copyright 2020 by Elsevier, Ltd. All rights reserved.
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Notice
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
Previous editions copyrighted 2010, 2002, 1987 by Churchill Livingstone, an affiliate of Elsevier, Inc.
Diane E. Spicer retains copyright of her images.
Library of Congress Control Number: 2018944861
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Senior Project Manager/Specialist: Carrie Stetz
Design Direction: Ryan Cook
Printed in China
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Dedication
To Alison, Sarah, Dan, Caroline, and Susie for all the joy you bring to my life.
J.S.T.
To my parents, Sasikala Raman and AK Raman.
K.K.
To my wife Katie for her support, and my children Adelyn, Jonas, and Rylan for their inspiration.
J.T.T.
Foreword
I little thought, when writing along with my colleagues the preface to the first edition of this textbook, that 33 years later I would be invited to provide the foreword to the fourth edition. Much has changed over that period, not least the tragically early loss of Fergus Macartney, one of the original editors. I am pleased to report that Elliot Shinebourne and Mike Tynan, our other original conspirators, continue to enjoy their retirement. For myself, it has been a pleasure to update the anatomical content of this latest version of the book. This would not have been possible without the efforts of Diane Spicer. Her photographs of the congenitally malformed heart that grace this fourth edition show the anatomic features with ever increasing accuracy and beauty. The major change in this fourth edition has been the remarkable shift in the geographical representation of the editorial team. Our first edition was an intentionally anglocentric affair. It is of minor historical interest that, when discussing the potential publication of the textbook with Andrew Stephenson, the publishing director of Churchill Livingstone at the time, we dined at their London offices. The upstairs storey of their premises, in Bentinck Street, had been the apartment, during the Second World War, of Guy Burgess, one of the notorious members of the ring of spies that chose to share our national secrets with the old Soviet Union. When preparing the content of our first edition, we took care to include European and transatlantic contributions. This proved possible through our collaborations with close friends and colleagues, particularly those working in Amsterdam and Pittsburgh. In our second edition, we were joined by two of our own fellows, Ted Baker and Mike Rigby, who had risen to their own prominence. The editorial team, nonetheless, remained firmly embedded in London. This then changed with the third edition. By this time, Elliot and Mike had chosen to hand on their editorial batons to Dan Penny and Andrew Redington. Trained by Elliot and Mike at the Brompton Hospital, they had, by then, achieved their own international recognition, being appointed to major positions in Melbourne and Toronto. This diaspora in itself was sufficient to bring a more international flavor to the team. The other major change in the third edition, however, was the addition of Gil Wernovsky, recognizing that the United States remained the epicenter of advances in the diagnosis and treatment of congenital cardiac disease. The book itself was significantly improved by the ability of our publisher to condense the editorial material into a single volume. The single volume, furthermore, was supported by electronic material and was in full color, with uniformly superb illustrations provided by Gemma Price.
Now, in this fourth edition, the textbook can truly claim to have achieved global prominence. This is true not only in terms of geography, but also the disciplines for which it aims to cater. Thus, Jim Tweddell joins the team as the first surgical editor, while Kathy Mussatto brings much-needed nursing excellence. Gil Wernovsky has now taken over the role of editorial director. The overall team is now based firmly in the United States. Another significant addition, nonetheless, is that the team is joined by Krishna Kumar. KK brings to the table the amazing advances being made in the Indian subcontinent. The written and illustrative components of the book, furthermore, are now supported by video material, collated and organized by Justin Tretter, with whom I have been particularly pleased to collaborate extensively over the last few years. We have been sorry to lose Dan Penny from our editorial team but pleased that he was still able to contribute in updating the chapters he produced and edited for the third edition.