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Edward Dolnick - The Seeds of Life

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Copyright 2017 by Edward Dolnick Published by Basic Books an imprint of - photo 1

Copyright 2017 by Edward Dolnick

Published by Basic Books, an imprint of Perseus Books, LLC, a subsidiary of Hachette Book Group, Inc.

All rights reserved. No part of this book may be reproduced in any manner whatsoever without written permission except in the case of brief quotations embodied in critical articles and reviews. For information, address Basic Books, 1290 Avenue of the Americas, New York, NY 10104.

Books published by Basic Books are available at special discounts for bulk purchases in the United States by corporations, institutions, and other organizations. For more information, please contact the Special Markets Department at Perseus Books, 2300 Chestnut Street, Suite 200, Philadelphia, PA 19103, or call (800) 810-4145, ext. 5000, or e-mail special. markets@perseusbooks.com .

D ESIGNED BY L INDA M ARK

Library of Congress Cataloging-in-Publication Data

Names: Dolnick, Edward, 1952 author.

Title: Seeds of life : from Aristotle to Da Vinci, from sharks teeth to frogs pants, the long and strange quest to discover where babies come from / Edward Dolnick.

Description: New York : Basic Books, [2017] | Includes bibliographical references and index.

Identifiers: LCCN 2016054195| ISBN 9780465082957 (hardcover) | ISBN 9780465094967 (ebook)

Subjects: LCSH: Human reproductionHistory. | Human reproductionMythology. | Human reproductionSocial aspects. | BISAC: SCIENCE / History. | HISTORY / Social History. | SCIENCE / Life Sciences / General.

Classification: LCC QP251 .D59 2017 | DDC 612.6dc23 LC record available at https://lccn.loc.gov/2016054195

LSC

E3-20170505-JV-PC

For Lynn, and Sam and Ben

Night and day, the ignorant as well as the learned give themselves over to the pleasure of making children. But no one knows how he has engendered his own progeny.

V ITTORE C ARDELINI , Italian physician and author, 1628

1490Leonardo da Vinci makes a cutaway drawing of a man and woman having sex.

1492Columbus sets sail.

1543Andreas Vesalius publishes one of the masterpieces in the history of anatomy.

1543Copernicus says that the Earth goes around the sun, not vice versa.

1628William Harvey shows that the heart is a pump.

1651Harvey declares that everything comes from the egg.

1669Jan Swammerdam argues that God created all the generations of animals at the dawn of time, one inside the next like Russian dolls.

1672Regnier de Graaf (almost) proves that female mammals have eggs.

1674Antony van Leeuwenhoek sees countless tiny animals, invisible to the naked eye, in a drop of pond water.

1677Leeuwenhoek sees spermatozoa by the millions.

1694Nicolaas Hartsoeker draws a miniature man inside a sperm cell.

1741Abraham Trembley cuts a tiny organism called a hydra into pieces. Miraculously, each piece grows into a complete creature.

1745French scientists propose a new theory of how living organisms develop: life is regulated not by clockwork but by a force akin to gravity.

1752Ben Franklin flies a kite during a thunderstorm and proves that lightning is electrical.

1770sLazzaro Spallanzani puts male frogs in boxer shorts.

1776American Revolution begins.

1791Luigi Galvani zaps frog legs with electricity.

1818Mary Shelley publishes Frankenstein.

1827Karl von Baer becomes the first to see a mammals egg.

1837Queen Victoria takes the throne.

1830s1860sCell theory emerges.

18611865The American Civil War lasts four long years.

1875Oscar Hertwig witnesses the union of sperm and egg.

I N CENTURIES TO COME THESE FIELDS AND WOODLANDS WILL shrink to tiny patches of green in a vast city. Londoners and tourists will feed ducks and swans here, and pose for giggling pictures. But today there are no crowds, no sightseers, no drifting sounds from the world outside. We are in an English royal park, the property of King Charles I. The king and his physician, William Harvey, are hunting deer. It is rutting season.

Neither Harvey nor the king has heard of a locked room mystery, where a body is found in impossible circumstances. Perhaps a dead man is discovered in a study locked from the inside, with a knife plunged into his back. Neither man has imagined such a thing. They are about to.

Harvey is a small man with raven-black hair and dark, darting eyes. Ambitious, impatient, and, as a friend put it, he radiates intensity. He is destined to soar into the medical pantheon for proving that the heart is a pump that sends the blood circulating around the body through an intricate network of arteries and veins.

Charles is slender, handsome, solemn, utterly convinced that God has set him above other mortals and that the king can do no wrong. He is destined to die at the hands of the English people, his head chopped off by a masked executioner and then held aloft by the hair while the crowd whoops in glee and gasps in shock at what it has done.

H ARVEY HAD PUBLISHED HIS ACCOUNT OF THE HEART IN 1628, A few years before the hunting excursion. The world denounced him. It was believed by the vulgar that Harvey complained, and all the physicians were against his opinion. For a man as combative as Harvey, that disdain served more as a spur than a rebuke. Harvey remained all his life a staunch seeing is believing man. Let others prattle on.

For uncounted ages, the heart had been the seat of the soul and the home of the emotions and insights that set humankind above other creatures. (When we talk today about a kind heart or a cold heart or speak of learning a poem by heart, of bygone beliefs.) What the sun was to the sky or the lion to the jungle, the heart was to the body. Now Harvey had demonstrated that this noble organ was in truth a wet and slimy machine.

The world would come around to Harveys view, though not for another two decades. In the end, the admiration would be universal. One dazzled follower would celebrate Harvey in verse: the Art / Of all the Wheels and Clock-work of the Heart.

At the time of his hunting venture with the king, that fame still lies ahead. Harvey is embattled, not acclaimed. But he knows what he has accomplished, even if the medical world has yet to catch on. With the riddle of the heart solved, Harvey has turned his attention to the greatest mystery of all. Since humankinds earliest days, men and women have wondered how new life comes into the world. How does sex lead to babies? Harvey intends to find out. He will learn, precisely, how mating creates life.

to hunt almost every week. Harvey has managed to enlist his king as his ally.

The kings huntsmen bring down a doe. Harvey, the most renowned anatomist of the age (and one of the last great anatomists to rely on what he can see with his naked eye), pushes close. Now he will show the king, who of curiosity, the secrets of conception and pregnancy. Together, they will gaze on a deer embryo in its earliest days. They are about to seewhat has never been revealed to anyone beforea small, round, glistening globule like an egg without a shell.

Harvey thrusts his knife into the does belly and cuts her open. Steam from the hot body rises into the chilly air. Harvey peers inside the animals womb, first avidly and then perplexedly. The king looks over his physicians shoulder. They see nothing!

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