Joseph R. Kraft - Diabetes Epidemic & You

Should Everyone Be Tested?

ABSOLUTELY NOT!

ONLY

THOSE CONCERNED ABOUT

THEIR FUTURE!

Joseph R. Kraft, MD, MS, FCAP

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Copyright 2008, 2011 Joseph R. Kraft, MD.

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the written prior permission of the author.

Note for Librarians: A cataloguing record for this book is available from Library and Archives Canada at www.collectionscanada.ca/amicus/index-e.html

Printed in the United States of America.

ISBN: 978-1-4251-6809-4 (sc)

ISBN: 978-1-4251-7812-3 (hc)

ISBN: 978-1-4251-6811-7 (e)

Trafford rev. 03/02/2011

Joseph R. Kraft, MD, MS, FCAP

Diplomate

American Board of Pathology

Anatomic pathology Clinical pathology

Diplomate

American Board of Nuclear Medicine

Chairman Emeritus

Department of Clinical Pathology

And Nuclear Medicine

St. Joseph Hospital

Chicago, IL USA

To Mary Catherine, the love of my life

To our family

Adrienne, Cheryl, Gregory, Stephen, Kevin, Mark, Joan, Michele, and

Regina

To our grandchildren

Kristen, Brian, Darren, Timothy, Raymond,

Nicholas, Christopher, Nicole, Alexandra, Anna, Chloe and Conrad

To our great-grandchildren

Braiden, Taylor, and Kathryn Nicole

For whom it is hoped that the Diabetes Epidemic will be conquered soon.

Contents

PREFACE-2011

Diabetes Epidemic and You

The subsequent book reviews were received following the first printing in 2008.

Diabetes Epidemic and You is superbly written, in a language that is accessible to the general public and yet precise enough for physicians. It is a difficult thing to achieve such clarity. Besides, it is a complete book that includes all related subjects in perfect manner.

Prof. Dr. Pedro Luiz Mangabeira Albernaz

Professor of Otorhinolaryngology

Escola Paulista de Medicina

Universidade Federal de Sao Paulo

Sao Paulo, Brasil

The International Tinnitus Journal Volume 15, Number 1, 2009

Joseph Kraft has written a book entitled Diabetes Epidemic and You. The subtitle is even more important and timely: Should Everyone Be Tested? Absolutely Not! Only Those Concerned About Their Future! In this very speedily readable book, Dr. Kraft outlines the history of diabetes and the discovery of insulin and its assays. He then goes on to relate his experience with 14,384 assays from 1972 through 1998. From there, the author puts together the relationship of insulin levels, blood sugar, and diabetes.

To complete the book, the second part compiles the age distribution of these oral glucose tolerances with insulin assays. This comparison not so subtly reveals the importance of this testing from age 3 to 90+ years.

This wonderful written book is suitable both for the public and for the profession. It is a treasure of knowledge and experience not otherwise available. This work should be required reading for all medical students, endocrinologists, otolaryngologists, and anybody interested in their future-and especially for physicians concerned about their future and that of their patients.

Kenneth H. Brookler, MD, MS, FRCSC

Clinical Professor of Otolaryngology

New York Medical College

Valhalia, New York

The International Tinnitus Journal Volume 15, Number 1 2009

This is a wonderful text both for the public and for our profession because of the tremendous amount of knowledge that reflects what we do know and what can occur later. There is no question that the bodys biochemistry and neural mechanisms rely on our intake of food or exposure to other chemicals. Therefore, as diabetes affects these entities, they also affect our body in relation to all other illnesses.

This is a superb textbook that should be read by the public, by members of our profession while in training, and those who are in practice so that they will begin to understand and expect what is occurring biochemically. It is a book for the present and for the future, and it deserves great commendations.

Wallace Rubin, M.D.

Clinical Professor, Department of Otolaryngology Louisiana State University School of Medicine New Orleans, LA

The goal of this book is to awaken the silent millions with undiagnosed diabetes to combat the Diabetes epidemic beginning with you-and I do mean you. states the author, Joseph R. Kraft, MD, chairman of the Department of Clinical Pathology and Nuclear Medicine, St. Joseph Hospital, Chicago, Illinois, 1962-1998.

In a comprehensive, well planned manner, the book integrates and provides to the medical community, clinicians, research professionals, and patients an extensive autopsy and clinical pathology experience for a practical approach to the diagnosis, treatment, and control of the pathogenesis of type 2 diabetes. The earliest diagnosis of prediabetes is hyperinsulin, type 2 diabetes, identified by the oral glucose tolerance test with insulin assay with normal glucose tolerance.

Since 1921, the oral glucose tolerance test has been an established procedure for the early diagnosis of diabetes. The focus of the reported clinical experience in this book is the application since 1972 at St. Josephs Hospital of the oral glucose tolerance test with insulin assays for the early diagnosis of diabetes. This test has provided the earliest diagnosis of prediabetes and diabetes even when the blood sugars were normal.

Dr. Krafts book is recommended as a source of information to professionals and patients of all ages interested in the maintenance of good health. All join with the author in attempting to influence and limit the clinical progression of the diabetes epidemic. This volume is a step forward for achieving the authors ultimate goal: the prevention of the pathology of diabetes mellitus and cardiovascular disease.

Abraham Shulman, M.D., FACS

Professor Emeritus Clinical Otolaryngology

State University of New York

Health Science Center at Brooklyn, New York

The earliest identification of diabetes persists as an enigma and a persistent challenge to international clinical medicine. William Osler, M.D., in his classic text, The Principles and Practice of Medicine (1892) was unable to identify a beginning of diabetes other than hyperglycemia. However, he noted age differences. Diabetes beginning in children, all of whom had a short survival and diabetes beginning in adulthood, had much in common. There were no cures and no ultimate survival.

In adult diabetes, Osler noted frequent urination as an early sign of diabetes. The urine did not always contain sugar. Occasionally, diabetes insipidus was identified. Unknown at that time was that arteriosclerosis of the kidneys could elevate the renal threshold for sugar thereby resulting in negative urines.

Doctor Osler, a distinguished Professor of Medicine, John Hopkins University, was fully aware that the autopsy was a pillar of medicine. He personally performed many autopsies. His pathology dissertations were extensive, especially on arteriosclerosis equal to that of today. Dr. Osler was a physician, a clinician, and truly a clinical pathologist.