Mauro Monteiro Correia - Colorectal Cancer Liver Metastases: A Comprehensive Guide to Management

This Springer imprint is published by the registered company Springer Nature Switzerland AG

The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

This book was originally conceptualized based on our observed need for the practicing clinician to have complete source under one cover that specifically focuses on all aspects of the complex and multidisciplinary management of colorectal liver metastases. Despite an increased emphasis on screening and prevention, colorectal cancer remains one of the most common malignancies worldwide, with an alarming increasing incidence in young patients as well as in many developing countries. Among those diagnosed with this disease, about half will develop metastases, most of which will be involving or confined to the liver. Unlike some other gastrointestinal malignancies where any advanced disease is typically treated with systemic therapies alone, patients with hepatic colorectal metastases are often offered various therapies, including surgical resection, other liver-directed therapies, and combined approaches. In selected cases, long-term survival and even potential for cure may be possible.

Information in this book and the manner in which it is written was designed both for the general clinician or trainee who cares for these cancer patients, as well as for those with specific focus and practice managing patients with liver metastases. We have paid particular attention to providing only the most relevant and up-to-date information necessary for a clinician of different specialties to help manage these patients. More importantly, our goal in this book is to emphasize the importance for anintegrated and multidisciplinarymanagement approach of this disease.

As one looks thought the table of contents, they will appreciate the complexity and breath of the multidisciplinary approach to patients with hepatic metastases. The book is written by an international team of world-renowned authorities in various specialties, covering topics in their respective areas of expertise. It aims to provide a fully current and referenced text that is succinct as possible, but comprehensive and detailed when necessary. It spans topics ranging from tumor biology, diagnosis, and staging, to advanced aspects of surgical technique. It provides the most updated knowledge in this rapidly advancing field, with specific emphasis on the most complex and multidisciplinary components of care. Debatable topics are discussed by highly regarded authorities, addressing controversies from different perspectives.

We are grateful to our contributors, as well as to our patients who have taught us the importance of much of the subject matter in this book. We believe the result of this comprehensive textbook will serve as an excellent foundation for the understanding of the underlying disease biology, assessment, and patient risk stratification, which are necessary to appropriately select patients for therapy, with the goal of improving survival and quality of life of colorectal cancer patients with liver-only or liver-dominant disease.