Amy L. Dunn - Pediatric Bleeding Disorders: A Clinical Casebook

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When this book was conceived, the editors were partners at Nationwide Childrens Hospital in Columbus, Ohio. The editors share a lifelong passion for clinical pediatric hemostasis, along with a similar passion for mentorship and education. We also realize the value of having partners and friends who share our interests. The field of pediatric hemostasis has evolved dramatically over the last decade as new interventions such as gene therapy, antibody-based therapies, and cellular therapies become realities; significant time and effort must be dedicated to learning about how and when to use these options. In addition, hemostasis testing is evolving, and increasingly, knowledge about the power of genetic testing and global hemostatic assays is vitally important. Categorical clinical training schedules, however, have increasing demands because every aspect of hematology, oncology, and bone marrow transplant is complex and rapidly evolving. For this reason, Dr. Bryce A. Kerlin had the vision to create a fourth year hemostasis/thrombosis fellowship to meet the training needs of future generations of pediatric hemostasis physicians. The fellowship provides 12 years of protected time, individualized to the trainees wants and needs. It also provides the opportunity to travel to relevant meetings such as the American Society of Hematology, Hemophilia Academy, and the Hemostasis and Thrombosis Research Society annual meetings. Our fellows have benefitted from these meetings to develop their own relationships and collaborators in the field. Fortunately, a local benefactor, Ms. Joan Wallick shared Dr. Kerlins vision, and our fellowship is endowed in her name. Our team has benefitted enormously from the excitement and enthusiasm of our trainees, and we have all grown because of this program. The fellows have all produced important and impactful academic works on a variety of hemostasis related projects.

As the editors planned this book, we decided to merge our passions for hemostasis and mentorship. Each editor paired with a former fellow who had completed either a categorical or fourth year fellowship with us. Each pair aimed to create clinical vignettes that would be approachable and illustrative of common scenarios encountered in pediatric hematology practice. The aim was to work through a differential diagnosis and initial treatment approach to each scenario and to offer a few clinical pearls at the end of each chapter. As so often happens in academic life, this group of collaborators no longer all work in the same city, but the collaborations, mentoring, and friendships continue despite physical distance. We dedicate this book to the generosity of Ms. Wallick, the spirit of mentorship, the patients and families who inspire us to keep learning,and all those who love the clinical conundrums associated with a vibrant pediatric hemostasis-thrombosis program.