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Eduardo E. Benarroch - Mayo Clinic Medical Neurosciences: Organized by Neurologic System and Level

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Eduardo E. Benarroch Mayo Clinic Medical Neurosciences: Organized by Neurologic System and Level

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Fully updated and revised according to student feedback, the sixth edition of Mayo Clinic Medical Neurosciences: Organized by Neurologic System and Level provides a systematic approach to anatomy, physiology, and pathology of the nervous system inspired by the neurologists approach to solving clinical problems. This volume has 4 sections: 1) an overview of the neurosciences necessary for understanding anatomical localization and pathophysiologic characterization of neurologic disorders; 2) an approach to localizing lesions in the 7 longitudinal systems of the nervous system; 3) an approach to localizing lesions in the 4 horizontal levels of the nervous system; and 4) a collection of clinical problems. This book provides the neuroscience framework to support the neurologist in a clinical setting and is also a great resource for neurology and psychiatry board certifications. This is the perfect guide for all medical students and neurology, psychiatry, and physical medicine residents at early stages of training.New to This Edition- A chapter devoted to multiple-choice questions for self-assessment- Discussion of emerging concepts in molecular, cellular, and system neurosciences- New chapters on emotion and consciousness systems- Incorporation of new discoveries in neuroimaging and an appendix for tables of medications commonly used to treat neurologic disordersBack in 1978, the first edition of Mayo Clinic Medical Neurosciences revolutionized our approach to teaching by aligning neuroscience knowledge to a clinicians approach to patient assessment. From those historical roots, the authors of this sixth edition set out on a daring enterprise to produce an updated and reorganized book. What follows is an erudite, insightful, and intellectually stimulating journey as we are led from gene to connectome and from perception to consciousness. It is a tailor made compendium that provides critical insight on applied neurosciences. Rich and detailed, its an invaluable reference for anyone inculcated into the enchanted landscape of the basic and clinical neurosciences. This book needs to be savored one page at a time.--Jose Biller, MD, FACP, FAAN, FANA, FAHA, Professor and Chairman, Department of Neurology, Loyola University Chicago, Stritch School of Medicine, Chicago, ILThis newest edition of Medical Neurosciences from the team at the Mayo Clinic presents neuroscience in an organized, systematic approach with clearly defined objectives for each chapter as well as a plethora of helpful vignettes which demonstrate the important clinical correlations for the reader. The writing style is very easy to follow and engaging. Key points for each chapter highlight the most high-yield teaching points and are helpful for students preparing for national board examinations.--Joseph E. Safdieh, MD, FAAN, Lewis and Rachel Rudin Foundation Education Scholar, Vice Chair for Education and Associate Professor, Department of Neurology, Weill Cornell Medical College, New York, NYWhat makes this book so unique is that it is a basic neuroscience book written by expert neurologic clinicians and educators, who also happen to be remarkably knowledgeable about basic neuroscience, so that every aspect of the text is written with the ultimate goal of each of us providing the most informed care to our patients with neurologic disorders. Although written as a medical education text for medical students regardless of ultimate specialty, this book is even of tremendous value for those seasoned neurologic clinicians among us, to help us learn, or relearn, the basic neuroscience that is so integral to the optimal diagnosis and management of our patients. --Steven L. Lewis, MD, Chief, Division of Neurology, Lehigh Valley Health Network, Allentown, PA, Editor-in-Chief, Continuum: Lifelong Learning in Neurology

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MAYO CLINIC MEDICAL NEUROSCIENCES SIXTH EDITION MAYO CLINIC SCIENTIFIC PRESS - photo 1
MAYO CLINIC MEDICAL NEUROSCIENCES
SIXTH EDITION
MAYO CLINIC SCIENTIFIC PRESS

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The triple-shield Mayo logo and the words MAYO, MAYO CLINIC, and MAYO CLINIC SCIENTIFIC PRESS are marks of Mayo Foundation for Medical Education and Research.

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Oxford University Press is a department of the University of Oxford. It furthers the Universitys objective of excellence in research, scholarship, and education by publishing worldwide. Oxford is a registered trade mark of Oxford University Press in the UK and certain other countries.

Published in the United States of America by Oxford University Press 198 Madison Avenue, New York, NY 10016, United States of America.

2018 Mayo Foundation for Medical Education and Research 2018

Fifth edition 2008 by Informa Healthcare USA, Inc.

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior permission of Mayo Foundation for Medical Education and Research. Inquiries should be addressed to Scientific Publications, Plummer 10, Mayo Clinic, 200 First St SW, Rochester, MN 55905.

You must not circulate this work in any other form and you must impose this same condition on any acquirer.

Library of Congress Cataloging-in-Publication Data

Names: Benarroch, Eduardo E., author. | Cutsforth-Gregory, Jeremy K., author. | Flemming, Kelly D., author. | Mayo Clinic.

Title: Mayo Clinic medical neurosciences : organized by neurologic systems and levels / Eduardo E. Benarroch, Jeremy K. Cutsforth-Gregory, Kelly D. Flemming.

Other titles: Medical neuroscience

Description: Sixth edition. | Rochester, MN : Mayo Clinic Scientific Press ;

New York, NY: Oxford University Press, [2017] | Preceded by Mayo Clinic medical neurosciences. 5th ed. / edited by Eduardo E. Benarroch [et al]. c2008. | Includes bibliographical references and index.

Identifiers: LCCN 2017017051 | ISBN 9780190209407 (alk. paper) eISBN 9780190209421

Subjects: | MESH: Nervous System Diseases | Nervous System

Classification: LCC RC348 | NLM WL 140 |

DDC 616.8dc23

LC record available at https://lccn.loc.gov/2017017051

Mayo Foundation does not endorse any particular products or services, and the reference to any products or services in this book is for informational purposes only and should not be taken as an endorsement by the authors or Mayo Foundation. Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, express or implied, with respect to the contents of the publication. This book should not be relied on apart from the advice of a qualified health care provider.

The authors, editors, and publisher have exerted efforts to ensure that drug selection and dosage set forth in this text are in accordance with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, readers are urged to check the package insert for each drug for any change in indications and dosage and for added wordings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug.

Some drugs and medical devices presented in this publication have US Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care providers to ascertain the FDA status of each drug or device planned for use in their clinical practice.

To the medical students and residents of the Mayo Clinic College of Medicine and Science, who have provided the stimulus for this venture by teaching us as we have taught them, who have helped us refine our objectives and methods of presentation, and who through their enthusiasm have encouraged us to prepare another edition of this book.

Preface to the Sixth Edition

The first edition of Mayo Clinic Medical Neurosciences, published in 1978, presented an organization of knowledge of the nervous system based on the neurologists approach to clinical problems. For medical students and residents alike, this framework served as an effective foundation on which to build knowledge in the classroom and at the bedside. Continued advances in knowledge of the nervous system required updating the text through the previous 5 editions.

Increasingly rapid expansion in understanding the normal brain and its responses to disease over the past 9 years demanded yet another revision for this, the Sixth Edition. Whereas the primary approach here is the same as in previous editions and aims to provide basic neuroscience concepts to solve clinical problems, this new edition has incorporated new information on emerging concepts in molecular, cellular, and system neurosciences, as well as neuroimaging approaches to reveal normal brain function and neurologic disease. This information is important for understanding neurologic disorders, ranging from abnormalities in gene, protein, synapse, or circuit function to dysfunction of widespread brain networks involved in sensory processing, motor control, homeostasis, behavioral state, emotion, and cognition.

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