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Rubin Robert H. Pfaff Donald W. - Hormone/Behavior Relations of Clinical Importance

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A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimers, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area. - Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented) - Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions - Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader - Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimers, affective disorders) - Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists.

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HormoneBehavior Relations of Clinical Importance Endocrine Systems Interacting - photo 1
Hormone/Behavior Relations of Clinical Importance
Endocrine Systems Interacting with Brain and Behavior

First Edition

Robert T. Rubin

Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California

Donald W. Pfaff

The Rockefeller University, New York, New York

Academic Press
Amsterdam Boston Heidelberg London New York Oxford
Paris San Diego San Francisco Singapore Sydney Tokyo
Academic Press is an imprint of Elsevier

Copyright

Academic Press is an imprint of Elsevier

Linacre House, Jordan Hill, Oxford, OX2 8DP, UK

525 B Street, Suite 1900, San Diego, CA 92101-4495, USA

Copyright 2009 Elsevier Inc. All rights reserved

Material in the work originally appeared in Hormones, Brain and Behavior, 2nd Edition , edited by D. W. Pfaff, A. P. Arnold, A. M. Etgen, S. E. Fahrbach and R.T. Rubin (Elsevier Inc 2009)

The following articles are US government works in the public domain and are not subject to copyright:

GONADAL HORMONES AND BEHAVIOR IN WOMEN: CONCENTRATIONS

VERSUS CONTEXT

NEUROREGULATORY PEPTIDES OF CENTRAL NERVOUS SYSTEM

ORIGIN: FROM LABORATORY TO CLINIC

THE NEUROENDOCRINOLOGY OF MOOD DISORDERS

HUMAN IMMUNODEFICIENCY VIRUS

AND ACQUIRED IMMUNODEFICIENCY SYNDROME

NEUROENDOCRINE ASPECTS OF POST-TRAUMATIC STRESS DISORDER

No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher

Permissions may be sought directly from Elseviers Science & Technology Rights Department in Oxford, UK: phone (+ 44) (0) 1865 843830; fax (+ 44) (0) 1865 853333; email: ), and selecting Obtaining permission to use Elsevier material

Notice

No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation or any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made

British Library Cataloguing in Publication Data

A catalogue record for this book is available from the British Library

Library of Congress Catalog Number: 2009927235

ISBN: 978-0-12-374926-0

For information on all Elsevier publications

visit our website at www.elsevierdirect.com

PRINTED AND BOUND IN CHINA

09 10 11 12 13 10 9 8 7 6 5 4 3 2 1

Contributors RA Allison 29 Transsexualism CIGNA Medical Group of - photo 2

Contributors

R.A. Allison (29, Transsexualism), CIGNA Medical Group of Arizona, Phoenix, AZ, USA

L. Baor (28, Assisted Reproduction in Infertile Women), Tel-Aviv, Israel

S.L. Berga (22, Premenstrual Dysphoric Disorder), Emory University, Atlanta, GA, USA

K.J. Berkley (36, Pain: Sex/Gender Differences), Florida State University, Tallahassee, FL, USA

M. Bettendorf (30, Disorders of Salt and Fluid Balance), University Clinic of Heidelberg, Heidelberg, Germany

S. Bocklandt (10, The Biology of Sexual Orientation and Gender Identity), UCLA School of Medicine, Los Angeles, CA, USA

L. Borg (35, Short-Acting Opiates vs. Long-Acting Opioids), The Rockefeller University, New York, NY, USA

G.D. Braunstein (19, Diseases of Hypothalamic Origin), Cedars-Sinai Medical Center, Los Angeles, CA, USA

R.S. Bridges (13, Prolactin Actions in the Brain), Tufts University School of Veterinary Medicine, North Grafton, MA, USA

W. Byne (11, Sexual Orientation in Men and Women), Mount Sinai School of Medicine, New York, NY, USA

L. Cahill (6, Sex Differences in Human Brain Structure and Function), University of California, Irvine, CA, USA

J.D. Carmichael (19, Diseases of Hypothalamic Origin), Cedars-Sinai Medical Center, Los Angeles, CA, USA

B.J. Carroll (21, Mood Disorders), Pacific Behavioral Research Foundation, Carmel, CA, USA

M.B.C.M. Cools (26, Genetic Defects of Female Sexual Differentiation), Ghent University, Ghent, Belgium

T.J. Creel (7, Sex Differences in CNS Neurotransmitter Influences on Behavior), Saint Vincent College, Latrobe, PA, USA

L. Czibere (1, Genetic Transmission of Behavior and Its Neuroendocrine Correlates), Max Planck Institute of Psychiatry, Munich, Germany

M. Daly (12, Sex Differences in Competitive Confrontation and Risk-taking), McMaster University, Hamilton, ON, Canada

A.B. Dessens (26, Genetic Defects of Female Sexual Differentiation), Sophia Childrens Hospital/Erasmus MC, Rotterdam, The Netherlands

S.L.S. Drop (26, Genetic Defects of Female Sexual Differentiation), Sophia Childens Hospital/Erasmus MC, Rotterdam, The Netherlands

N.N. Ekhator (16, Brain Peptides: From Laboratory to Clinic), University of Cincinnati, Cincinnati, OH, USA

J. Emens (17, Melatonin Actions in the Brain), Oregon Health and Science University, Portland, OR, USA

A.J. Fiocco (25, Aging and Alzheimers Disease), University of California, San Francisco, CA, USA

C.A. Frye (15, Neurosteroids: From Basic Research to Clinical Perspectives), University at Albany-State University of New York, Albany, NY, USA

S.N. Garfinkel (20, Stress and Anxiety Disorders), University of Michigan School of Medicine, Ann Arbor, MI, USA

N.E. Gentile (2, Hypothalamic-Pituitary-Adrenal Cortical Axis), Saint Vincent College, Latrobe, PA, USA

T.D. Geracioti, Jr. (16, Brain Peptides: From Laboratory to Clinic), University of Cincinnati, Cincinnati, OH, USA

E.S. Ginsburg (32, Alcohol Abuse: Endocrine Concomitants), Brigham and Womens Hospital, Boston, MA, USA

M.B. Goetz (38, Human Immunodeficiency Virus and AIDS), VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA

L.J. Gooren (11, Sexual Orientation in Men and Women), VU University Medical Center, Amsterdam, The Netherlands

D.R. Grattan (13, Prolactin Actions in the Brain), University of Otago, Dunedin, New Zealand

J.A. Grootegoed (26, Genetic Defects of Female Sexual Differentiation), Erasmus MC, Rotterdam, The Netherlands

B. Hambsch (1, Genetic Transmission of Behavior and Its Neuroendocrine Correlates), Max Planck Institute of Psychiatry, Munich, Germany

V.L. Harsh (4, Hypothalamic-Pituitary-Gonadal Axis in Women), National Institutes of Health, Bethesda, MD, USA

M. Hines (8, Gonadal Hormones and Sexual Differentiation of Human Brain and Behavior), University of Cambridge, Cambridge, UK

A. Holdcroft (36, Pain: Sex/Gender Differences), Imperial College London, London, UK

J. Imperato-McGinley (27, Genetic Defects of Male Sexual Differentiation), Weill Medical College of Cornell University, New York, NY, USA

R.T. Joffe (3, Hypothalamic-Pituitary-Thyroid Axis), New Jersey Medical School, Maplewood, NJ, USA

B.A. Kaminski (9, Human Puberty: Physiology and Genetic Regulation), Rainbow Babies and Childrens Hospital, Cleveland, OH, USA

J. Kaskow (16, Brain Peptides: From Laboratory to Clinic), University of Pittsburgh Medical Center, Pittsburgh, PA, USA

I. Kravets (35, Short-Acting Opiates vs. Long-Acting Opioids), The Rockefeller University, New York, NY, USA

M.J. Kreek (35, Short-Acting Opiates vs. Long-Acting Opioids), The Rockefeller University, New York, NY, USA

R. Landgraf (1, Genetic Transmission of Behavior and Its Neuroendocrine Correlates), Max Planck Institute of Psychiatry, Munich, Germany

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