Urban Laszlo - Antitargets and Drug Safety

Edited by R. Mannhold, H. Kubinyi, G. Folkers

Editorial Board

H. Buschmann, H. Timmerman, H. van de Waterbeemd

Keser, Gyrgy M./Swinney, David C. (Eds.)

Kinetics and Thermodynamics of Drug Binding

2015

ISBN: 978-3-527-33582-4

Vol. 65

Pfannkuch, Friedlieb/Suter-Dick, Laura (Eds.)

Predictive Toxicology

From Vision to Reality

2014

ISBN: 978-3-527-33608-1

Vol. 64

Kirchmair, Johannes (Ed.)

Drug Metabolism Prediction

2014

ISBN: 978-3-527-33566-4

Vol. 63

Vela, Jos Miguel/Maldonado, Rafael/Hamon, Michel (Eds.)

In vivo Models for Drug Discovery

2014

ISBN: 978-3-527-33328-8

Vol. 62

Liras, Spiros/Bell, Andrew S. (Eds.)

Phosphodiesterases and Their Inhibitors

2014

ISBN: 978-3-527-33219-9

Vol. 61

Hanessian, Stephen (Ed.)

Natural Products in Medicinal Chemistry

2014

ISBN: 978-3-527-33218-2

Vol. 60

Lackey, Karen/Roth, Bruce (Eds.)

Medicinal Chemistry Approaches to Personalized Medicine

2013

ISBN: 978-3-527-33394-3

Vol. 59

Brown, Nathan (Ed.)

Scaffold Hopping in Medicinal Chemistry

2013

ISBN: 978-3-527-33364-6

Vol. 58

Hoffmann, Rmy/Gohier, Arnaud/Pospisil, Pavel (Eds.)

Data Mining in Drug Discovery

2013

ISBN: 978-3-527-32984-7

Vol. 57

Dmling, Alexander (Ed.)

Protein-Protein Interactions in Drug Discovery

2013

ISBN: 978-3-527-33107-9

Vol. 56

Kalgutkar, Amit S./Dalvie, Deepak/Obach, R. Scott/Smith, Dennis A.

Reactive Drug Metabolites

2012

ISBN: 978-3-527-33085-0

Vol. 55

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Print ISBN: 978-3-527-33511-4

ePDF ISBN: 978-3-527-67367-4

ePub ISBN: 978-3-527-67366-7

Mobi ISBN: 978-3-527-67365-0

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Daniel J. Antoine

University of Liverpool

Institute of Translational Medicine

Department of Molecular and Clinical Pharmacology

MRC Centre for Drug Safety Science

Liverpool L69 3GE

UK

Richard J. Brennan

Sanofi US

Preclinical Safety

DSAR

153 2nd Ave.

Waltham, MA 02451

USA

Kim L.R. Brouwer

The University of North Carolina at Chapel Hill

UNC Eshelman School of Pharmacy

Division of Pharmacotherapy and Experimental Therapeutics

Chapel Hill, NC 27599

USA

Jos S. Duca

Novartis Institutes for BioMedical Research

Computer Assisted Drug Discovery

100 Technology Square

Cambridge, MA 02139

USA

Berengere Dumotier

Novartis Institutes for BioMedical Research

Preclinical Safety/Cardiac Electrophysiology

Klybeckstrasse 141, WKL.136.178

4057 Basel

Switzerland

Gl Erdemli

Novartis Institutes for BioMedical Research

Center for Proteomic Chemistry

Ion Channel Group

250 Massachusetts Ave.

Cambridge, MA 02139

USA

Ramy Farid

Schrdinger, Inc.

120 West Forty-Fifth Street, 17th Floor

New York, NY 10036

USA

Alexander Fekete

Novartis Institutes for BioMedical Research

Preclinical Safety

Preclinical Secondary Pharmacology

250 Massachusetts Avenue

Cambridge, MA 02139

USA

Oliver Flint

Bristol-Myers Squibb

Pharmaceutical Candidate

Optimization

Discovery Toxicology

Liberty Drive

Newtown, PA 18940

USA

Gary Gintant

AbbVie

Integrated Science and Technology

Department of Integrative Pharmacology

Abbott Park Road

Abbott Park, IL 60064

USA

Andrea Greiter-Wilke

F. Hoffmann-La Roche Ltd.

Pharmaceuticals/Metabolic DTA

Grenzacherstrasse 124

4070 Basel

Switzerland

Brian Guth

Boehringer Ingelheim Pharma GmbH & Co. KG

General Pharmacology, Drug Discovery Support

Biberach an der Riss

Germany

Robert L. Hamlin

QTest Labs LLC and The Ohio State University

1900 Coffey Road

Columbus, OH 43210

USA

Jacques Hamon

Novartis Institutes for BioMedical Research

Preclinical Safety Profiling

Klybeckstrasse 141

4057 Basel

Switzerland

Andreas Hartmann

Novartis Institutes for BioMedical Research

Preclinical Safety

Klybeckstrasse

4057 Basel

Switzerland

Brett A. Howell

The Hamner Institutes for Health Sciences

The HamnerUNC Institute for Drug Safety Sciences

Research Triangle Park, NC 27709

USA

Daniel Hoyer

The University of Melbourne

Faculty of Medicine, Dentistry and Health Sciences

School of Medicine

Department of Pharmacology and Therapeutics

Parkville, Victoria 3010

Australia

and

The University of Melbourne

The Florey Institute of Neuroscience and Mental Health

30 Royal Parade

Parkville, Victoria 3052

Australia

and

The Scripps Research Institute

Department of Chemical Physiology

10550 North Torrey Pines Road

La Jolla, CA 92037

USA

Qi-Ying Hu

Novartis Institutes for BioMedical Research

Global Discovery Chemistry

100 Technology Square

Cambridge, MA 02139

USA

Haisong Ju

Novartis Institutes for BioMedical Research Head

Safety Pharmacology-US/Preclinical Safety

Novartis Pharmaceuticals Corporation

One Health Plaza

East Hanover, NJ 07936-1080

USA

Michael J. Keiser

University of California, San Francisco

Department of Pharmaceutical Chemistry

1700 4th Street

San Francisco, CA 94158

USA

and

University of California, San Francisco

Department of Bioengineering and

Therapeutic Sciences

1700 4th Street

San Francisco, CA 94158

USA

and

University of California, San Francisco

Institute for Neurodegenerative Diseases