Practical Clinical Electrophysiology
Second Edition
EDITORS
Peter J. Zimetbaum, MD
Richard A. and Susan F. Smith Professor of Cardiovascular Medicine
Harvard Medical School
Associate Chief and Clinical Director of Cardiology
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Alfred E. Buxton, MD
Josephson Ben-Haim Professor of Medicine
Harvard Medical School
Director, Cardiac Electrophysiology Fellowship
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Mark E. Josephson, MD
Herman C. Dana Professor of Medicine
Harvard Medical School
Chief of the Cardiovascular Division, Emeritus
Director, Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Acquisitions Editor: Sharon Zinner
Development Editor: Kristina Oberle
Editorial Coordinator: Emily Buccieri
Strategic Marketing Manager: Rachel Mante Leung
Senior Production Project Manager: Alicia Jackson
Design Coordinator: Holly McLaughlin
Manufacturing Coordinator: Beth Welsh
Prepress Vendor: SPi Global
2nd edition
Copyright 2018 Wolters Kluwer
2009 by LIPPINCOTT WILLIAM & WILKINS, a WOLTERS KLUWER business
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Printed in China
Library of Congress Cataloging-in-Publication Data
Names: Zimetbaum, Peter J., editor. | Josephson, Mark E., editor.
Title: Practical clinical electrophysiology / editors, Peter J. Zimetbaum, Mark E. Josephson.
Description: Second edition. | Philadelphia : Wolters Kluwer Health, [2018] |
Includes bibliographical references and index.
Identifiers: LCCN 2017034934 | ISBN 9781496371119
Subjects: | MESH: Arrhythmias, Cardiacphysiopathology | Electrophysiologic Techniques, Cardiacmethods | Arrhythmias, Cardiacdiagnosis | Arrhythmias, Cardiactherapy
Classification: LCC RC685.A65 | NLM WG 330 | DDC 616.1/28dc23 LC record available at https://lccn.loc.gov/2017034934
This work is provided as is, and the publisher disclaims any and all warranties, express or implied, including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.
This work is no substitute for individual patient assessment based upon healthcare professionals examination of each patient and consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data and other factors unique to the patient. The publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for any resulting diagnosis and treatments.
Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information sheet (the manufacturers package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or otherwise, or from any reference to or use by any person of this work.
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Dedication
To the memory of Mark E. Josephson, MD Our teacher, mentor, and dearest friend
Contributing Authors
Alfred E. Buxton, MD
Josephson Ben-Haim Professor of Medicine
Harvard Medical School
Director, Cardiac Electrophysiology Fellowship
Beth Israel Deaconess Medical Center
Boston, Massachusetts
The Basic Electrophysiology Study
Basic Principles in Clinical Electrophysiology
Mechanism of Tachycardias
Wolff-Parkinson-White Syndrome and Variants
David Callans, MD
Associate Director, Electrophysiology
University of Pennsylvania Health System
Professor of Medicine at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Philadelphia, Pennsylvania
Atrial Flutter
Ventricular Tachycardia
Elad Anter, MD
Assistant Professor of Medicine
Harvard Medical School
Director, Harvard Thorndike Electrophysiology Institute
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Ventricular Tachycardia
Fernando M. Contreras-Valdes, MD
Instructor of medicine
Harvard Medical School
Clinical electrophysiologist
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Pacemakers: Indications and Function
Pacemaker Troubleshooting
ICD Indications and Function
ICD Troubleshooting
Daniel R. Frisch, MD
Assistant Professor of Medicine
Division of Cardiology
Electrophysiology Section
Thomas Jefferson University
Philadelphia, Pennsylvania
Supraventricular Tachycardia
Emerson Liu, MD
Director, Electrophysiology Research and Innovation
Division of CV Medicine
Allegheny General Hospital
Pittsburgh, Pennsylvania
Anatomy in Clinical Electrophysiology
Yonathan F. Melman, MD/PhD
Electrophysiologist
Intermountain Healthcare
McKay-Dee Heart Rhythm Specialists
McKay-Dee Hospital
Ogden, Utah
Membrane and Cellular Electrophysiology
Sudden Death Syndromes
Amit Thosani, MD
Director, Cardiac Electrophysiology
Allegheny Health Network
Assistant Professor, Temple University School of Medicine
Pittsburgh, Pennsylvania
Anatomy in Clinical Electrophysiology
Jonathan W. Waks, MD
Clinical Cardiac Electrophysiologist
Beth Israel Deaconess Medical Center