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Ebrahim Ghafar-Zadeh - Emerging CMOS Capacitive Sensors for Biomedical Applications: A multidisciplinary approach

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Ebrahim Ghafar-Zadeh Emerging CMOS Capacitive Sensors for Biomedical Applications: A multidisciplinary approach
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CMOS-based sensors offer significant advantages to life science applications, such as non-invasive long-term recordings, fast responses and label-free processes. They have been widely applied in many biological and medical fields for the study of living cell samples such as neural cell recording and stimulation, monitoring metabolic activity, cell manipulation, and extracellular pH monitoring. Compared to other sensing techniques, capacitive sensors are low-complexity, high-precision, label-free sensing methods for monitoring cellular activities such as cell viability, proliferation and morphology.

The development of capacitive sensors for use in life sciences requires thorough knowledge of both the intended biological applications and CMOS circuitry. This book addresses the principles, design, implementation and testing, and packaging of CMOS circuits for these applications. Existing applications, markets, and potential future developments are also covered, plus the relevant biological protocols.

Emerging CMOS Capacitive Sensors for Biomedical Applications provides information and guidance for researchers and advanced students in the field of microelectronics who are looking to specialise in biological applications. It is also relevant to academic and industrial researchers already working in the biosensors field, who wish to expand their knowledge and keep abreast of new developments.

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Contents

IET MATERIALS, CIRCUITS AND DEVICES SERIES 63

Emerging CMOS Capacitive Sensors for Biomedical Applications

Emerging CMOS Capacitive Sensors for Biomedical Applications

A multidisciplinary approach

Ebrahim Ghafar-Zadeh and Saghi Forouhi

The Institution of Engineering and Technology

Published by The Institution of Engineering and Technology, London, United Kingdom

The Institution of Engineering and Technology is registered as a Charity in England & Wales (no. 211014) and Scotland (no. SC038698).

The Institution of Engineering and Technology 2022

First published 2021

This publication is copyright under the Berne Convention and the Universal Copyright Convention. All rights reserved. Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the Copyright, Designs and Patents Act 1988, this publication may be reproduced, stored or transmitted, in any form or by any means, only with the prior permission in writing of the publishers, or in the case of reprographic reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency. Enquiries concerning reproduction outside those terms should be sent to the publisher at the undermentioned address:

The Institution of Engineering and Technology
Michael Faraday House
Six Hills Way, Stevenage
Herts, SG1 2AY United Kingdom

www.theiet.org

While the authors and publisher believe that the information and guidance given in this work are correct, all parties must rely upon their own skill and judgement when making use of them. Neither the authors nor publisher assumes any liability to anyone for any loss or damage caused by any error or omission in the work, whether such an error or omission is the result of negligence or any other cause. Any and all such liability is disclaimed.

The moral rights of the authors to be identified as authors of this work have been asserted by him them in accordance with the Copyright, Designs and Patents Act 1988.

British Library Cataloguing in Publication Data
A catalogue record for this product is available from the British Library

ISBN 978-1-78561-915-1 (hardback)
ISBN 978-1-78561-916-8 (PDF)

Typeset in India by MPS Limited
Printed in the UK by CPI Group (UK) Ltd, Croydon

Other volumes in this series:

Volume 2Analogue IC Design: The current-mode approach C. Toumazou, F.J. Lidgey and D.G. Haigh (Editors)
Volume 3AnalogueDigital ASICs: Circuit techniques, design tools and applications R.S. Soin, F. Maloberti and J. France (Editors)
Volume 4Algorithmic and Knowledge-based CAD for VLSI G.E. Taylor and G. Russell (Editors)
Volume 5Switched Currents: An analogue technique for digital technology C. Toumazou, J.B.C. Hughes and N.C. Battersby (Editors)
Volume 6High-frequency Circuit Engineering F. Nibler et al.
Volume 8Low-power High-frequency Microelectronics: A unified approach G. Machado (Editor)
Volume 9VLSI Testing: Digital and mixed analogue/digital techniques S.L. Hurst
Volume 10Distributed Feedback Semiconductor Lasers J.E. Carroll, J.E.A. Whiteaway and R.G.S. Plumb
Volume 11Selected Topics in Advanced Solid State and Fibre Optic Sensors S.M. Vaezi-Nejad (Editor)
Volume 12Strained Silicon Heterostructures: Materials and devices C.K. Maiti, N.B. Chakrabarti and S.K. Ray
Volume 13RFIC and MMIC Design and Technology I.D. Robertson and S. Lucyzyn (Editors)
Volume 14Design of High Frequency Integrated Analogue Filters Y. Sun (Editor)
Volume 15Foundations of Digital Signal Processing: Theory, algorithms and hardware design P. Gaydecki
Volume 16Wireless Communications Circuits and Systems Y. Sun (Editor)
Volume 17The Switching Function: Analysis of power electronic circuits C. Marouchos
Volume 18System on Chip: Next generation electronics B. Al-Hashimi (Editor)
Volume 19Test and Diagnosis of Analogue, Mixed-signal and RF Integrated Circuits: The system on chip approach Y. Sun (Editor)
Volume 20Low Power and Low Voltage Circuit Design with the FGMOS Transistor E. Rodriguez-Villegas
Volume 21Technology Computer Aided Design for Si, SiGe and GaAs Integrated Circuits C.K. Maiti and G.A. Armstrong
Volume 22Nanotechnologies M. Wautelet et al.
Volume 23Understandable Electric Circuits M. Wang
Volume 24Fundamentals of Electromagnetic Levitation: Engineering sustainability through efficiency A.J. Sangster
Volume 25Optical MEMS for Chemical Analysis and Biomedicine H. Jiang (Editor)
Volume 26High Speed Data Converters A.M.A. Ali
Volume 27Nano-scaled Semiconductor Devices E.A. Gutirrez-D (Editor)
Volume 28Security and Privacy for Big Data, Cloud Computing and Applications L. Wang, W. Ren, K.R. Choo and F. Xhafa (Editors)
Volume 29Nano-CMOS and Post-CMOS Electronics: Devices and modelling Saraju P. Mohanty and Ashok Srivastava
Volume 30Nano-CMOS and Post-CMOS Electronics: Circuits and design Saraju P. Mohanty and Ashok Srivastava
Volume 32Oscillator Circuits: Frontiers in design, analysis and applications Y. Nishio (Editor)
Volume 33High Frequency MOSFET Gate Drivers Z. Zhang and Y. Liu
Volume 34RF and Microwave Module Level Design and Integration M. Almalkawi
Volume 35Design of Terahertz CMOS Integrated Circuits for High-speed Wireless Communication M. Fujishima and S. Amakawa
Volume 38System Design with Memristor Technologies L. Guckert and E.E. Swartzlander Jr.
Volume 39Functionality-enhanced Devices: An alternative to Moores Law P.-E. Gaillardon (Editor)
Volume 40Digitally Enhanced Mixed Signal Systems C. Jabbour, P. Desgreys and D. Dallett (Editors)
Volume 43Negative Group Delay Devices: From concepts to applications B. Ravelo (Editor)
Volume 45Characterisation and Control of Defects in Semiconductors F. Tuomisto (Editor)
Volume 47Understandable Electric Circuits: Key concepts, 2nd Edition M. Wang
Volume 48Gyrators, Simulated Inductors and Related Immittances: Realizations and applications R. Senani, D.R. Bhaskar, V.K. Singh and A.K. Singh
Volume 49Advanced Technologies for Next Generation Integrated Circuits A. Srivastava and S. Mohanty (Editors)
Volume 51Modelling Methodologies in Analogue Integrated Circuit Design G. Dundar and M.B. Yelten (Editors)
Volume 53VLSI Architectures for Future Video Coding M. Martina (Editor)
Volume 54Advances in High-power Fiber and Diode Laser Engineering Ivan Divliansky (Editor)
Volume 55Hardware Architectures for Deep Learning
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