Lester Packer - Vitamin C in Health and Disease (Antioxidants in Health and Disease, Vol 5)
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Vitamin C in Health and Disease (Antioxidants in Health and Disease, Vol 5)
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Provides an up-to-the-minute, comprehensive analysis of the most recent theoretical and clinical developments in vitamin C research--integrating a wide variety of interdisciplinary studies into a single-source volume. Highlights the redox properties of vitamin C, including regeneration, participation in antioxidant networks, and influence on atherosclerosis.
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LESTER PACKER, PH.D. University of California Berkeley, California
JRGEN FUCHS, PH.D., M.D. Johann Wolfgang Goethe University Frankfurt, Germany
1. Vitamin A in Health and Disease, edited by Rune Blomhoff
2. Biothiols in Health and Disease, edited by Lester Packer and Enrique Cadenas
3. Handbook of Antioxidants, edited by Enrique Cadenas and Lester Packer
4. Handbook of Synthetic Antioxidants, edited by Lester Packer and Enrique Cadenas
5. Vitamin C in Health and Disease, edited by Lester Packer and Jrgen Fuchs
Additional Volumes in Preparation
Lipoic Acid in Health and Disease, edited by Jrgen Fuchs, Lester Packer, and Guido Zimmer
Flavonoids in Health and Disease, edited by Catherine Rice-Evans and Lester Packer
Related Volumes
Vitamin E in Health and Disease: Biochemistry and Clinical Applications, edited by Lester Packer and Jrgen Fuchs
Free Radicals and Oxidation Phenomena in Biological Systems, edited by Marcel Roberfroid and Pedro Buc Calderon
Page i
Vitamin C in Health and Disease
edited by Lester Packer
University of California Berkeley, California
Jrgen Fuchs
Johann Wolfgang Goethe University Frankfurt, Germany
Page ii
Library of Congress CataloginginPublication Data
Vitamin C in health and disease / edited by Lester Packer, Jrgen Fuchs. p. cm.(Aantioxidants in health and disease ; 5) Includes index. ISBN 0-8247-9313-7 (hardcover : alk. paper) 1. Vitamin CHealth aspects. I. Packer, Lester. II. Fuchs, Jrgen. III. Series. [DNLM: 1. Ascorbic Acidphysiology. 2. Ascorbic Acid therapeutic use. 3. Ascorbic Acidchemistry. W1 AN884 v.5 1997 / QU 210 V8363 1997] 615'.328dc21 DNLM/DLC for Library of Congress 97-7703 CIP
The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the address below.
This book is printed on acid-free paper.
Copyright 1997 by Marcel Dekker, Inc. All Rights Reserved.
Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher.
Marcel Dekker, Inc. 270 Madison Avenue, New York, New York 10016
In June of 1992, 17 international researchers in the field of free radical and antioxidant biology and preventive medicine met at the village of Saas Fee, Switzerland, and drew up the Saas Fee Declaration to recognize the importance of prevention in medicine and health. Since then, hundreds of researchers from around the world have signed the declaration:
Saas Fee Declaration
On the significance of antioxidants in preventive medicine.
1. The intensive research on free radicals of the past 15 years by scientists worldwide has led to the statement in 1992 that antioxidant nutrients may have major significance in the prevention of a number of diseases. These include cardiovascular and cerebrovascular disease, some forms of cancer and several other disorders, many of which may be age-related.
2. There is now general agreement that there is a need for further work at the fundamental scientific level, as well as in large-scale randomized trials and in clinical medicine, which can be expected to lead to more precise information being made available.
3. The major objective of this work is the prevention of disease. This maybe achieved by use of antioxidants which are natural physiological substances. The strategy should be to achieve optimal intakes of these antioxidant nutrients as part of preventive medicine.
4. It is quite clear that many environmental sources of free radicals exist, such as ozone, sunlight, and other forms of radiation, smog, dust, and other atmospheric pollutants. The optimal intake of antioxidants provides a preventive measure against these hazards.
5. There is a great need for improvement in public awareness of the potential preventive benefits of antioxidant nutrient intake. There is overwhelming evidence that the antioxidant nutrients such as vitamin E, vitamin C, carotenoids, alpha-lipoic acid and others are safe even at very high levels of intake.
6. Moreover, there is now substantial agreement that government agencies, health professionals, and the media should promote information transfer to the general public, particularly when evidence exists that benefits for human health and public expenditure are overwhelming.
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