Ethan B. Russo - The Handbook of Cannabis Therapeutics: From Bench to Bedside

Handbook of Cannabis Therapeutics

From Bench to Bedside

THE HAWORTH PRESS

Haworth Series in Integrative Healing

Ethan Russo

Editor

The Last Sorcerer: Echoes of the Rainforest by Ethan Russo

Professionalism and Ethics in Complementary and Alternative Medicine by John Crellin and Fernando Ania

Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential by Franjo Grotenhermen and Ethan Russo

Modern Psychology and Ancient Wisdom: Psychological Healing Practices from the Worlds Religious Traditions edited by Sharon G. Mijares

Complementary and Alternative Medicine: Clinic Design by Robert A. Roush

Herbal Voices: American Herbalism Through the Words of American Herbalists by Anne K. Dougherty

The Healing Power of Chinese Herbs and Medicinal Recipes by Joseph P. Hou and Youyu Jin

Alternative Therapies in the Treatment of Brain Injury and Neurobehavioral Disorders: A Practical Guide edited by Gregory J. Murrey

Handbook of Cannabis Therapeutics: From Bench to Bedside edited by Ethan B. Russo and Franjo Grotenhermen

Handbook of Cannabis Therapeutics

From Bench to Bedside

Ethan B. Russo, MD

Franjo Grotenhermen, MD

Editors

First Published by

The Haworth Press, Inc., 10 Alice Street, Binghamton, NY 13904-1580.

Transferred to Digital Printing 2010 by Routledge

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2006 by The Haworth Press, Inc. All rights reserved. No part of this work may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, microfilm, and recording, or by any information storage and retrieval system, without permission in writing from the publisher.

PUBLISHERS NOTE

The development, preparation, and publication of this work has been undertaken with great care. However, the Publisher, employees, editors, and agents of The Haworth Press are not responsible for any errors contained herein or for consequences that may ensue from use of materials or information contained in this work. The Haworth Press is committed to the dissemination of ideas and information according to the highest standards of intellectual freedom and the free exchange of ideas. Statements made and opinions expressed in this publication do not necessarily reflect the views of the Publisher, Directors, management, or staff of The Haworth Press, Inc., or an endorsement by them.

This book is a compilation of articles previously published in the Journal of Cannabis Therapeutics: Studies in Endogenous, Herbal, and Synthetic Cannabinoids, 1(1) (2001): 5-70, 85-88; 1(2) (2001): 15-20; 1(3/4) (2001): 5-16, 103-132; 2(1) (2002): 3-57; 2(2) (2002): 51-79; 2(3/4) (2002): 5-34, 49-81, 103-131, 159-173; 3(1) (2003): 3-51; 3(4) (2003): 163-174; 4(1) (2004): 29-78, published by The Haworth Press, Inc.

This book has been published solely for educational purposes and is not intended to substitute for the medical advice of a treating physician. Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment may be required. While many potential treatment options are made herein, some or all of the options may not be applicable to a particular individual. Therefore, the author, editor, and publisher do not accept responsibility in the event of negative consequences incurred as a result of the information presented in this book. We do not claim that this information is necessarily accurate by the rigid scientific and regulatory standards applied for medical treatment. No warranty, expressed or implied, is furnished with respect to the material contained in this book. The reader is urged to consult with his/her personal physician with respect to the treatment of any medical condition.

Photographs by Ethan B. Russo. Medicine bottle from the collection of David Watson, HortaPharm, Amsterdam.

Cover design by Kerry E. Mack.

Library of Congress Cataloging-in-Publication Data

Handbook of cannabis therapeutics : from bench to bedside / Ethan B. Russo, Franjo Grotenhermen, editors.

p. cm.

A compilation of selected articles from the Journal of cannabis therapeutics... from 2001 to 2004Introd.

Includes bibliographical references and index.

ISBN-13: 978-0-7890-3096-2 (hard : alk. paper)

ISBN-10: 0-7890-3096-9 (hard : alk. paper)

ISBN-13: 978-0-7890-3097-9 (soft : alk. paper)

ISBN-10: 0-7890-3097-7 (soft : alk. paper)

1. CannabisTherapeutic useHistory. I. Russo, Ethan. II. Grotenhermen, Franjo. III. Journal of cannabis therapeutics.

[DNLM: 1. CannabisCollected Works. 2. PhytotherapymethodsCollected Works. 3. CannabinoidshistoryCollected Works. 4. Cannabinoidstherapeutic useCollected Works. 5. Plant Extractstherapeutic useCollected Works. WB 925 H236 2006]

RM666.C266H36 2005

615.7827dc22

2005029271

Ethan B. Russo, MD, is Adjunct Associate Professor in the Department of Pharmaceutical Sciences at the University of Montana and Clinical Associate Professor in the Department of Medicine at the University of Washington. He is board certified in neurology with a special qualification in child neurology. He frequently lectures to undergraduate and graduate students in the fields of pharmacy, psychology, sports medicine, interpersonal communications, and physical therapy, among others. He has had a lifetime interest in medicinal plants.

Dr. Russo has written numerous peer-reviewed articles on ethnobotany, herbal medicine, and cannabis, and has lectured internationally on these topics. He has published numerous peer-reviewed articles on ethnobotany, herbal medicine, and cannabis, and he has lectured nationally on those subjects. He is the author/editor of the Handbook of Psychotropic Herbs; Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential; Cannabis Therapeutics in HIV/AIDS; Women and Cannabis: Medicine, Science, and Sociology; and a novel, The Last Sorcerer: Echoes of the Rainforest (Haworth). For four years Dr. Russo served as editor of the Journal of Cannabis Therapeutics.

Franjo Grotenhermen, MD, has worked in the fields of internal medicine, surgery, and integrative medicine. Since 1994 he has been researching medical uses of hemp at the Nova Institut. He is also a member of the working group on quality of life for cancer patients at the Department of Internal Medicine at the University of Cologne.

Dr. Grotenhermen is founder and executive director of the Association for Cannabis as Medicine (ACM) in Germany and of the International Association for Cannabis as Medicine (IACM). He is author and co-author of a number of books, book chapters, and articles on the therapeutic uses, pharmacology, and toxicology of cannabis and cannabinoids; most have appeared in German.

Handbook of Cannabis Therapeutics

2006 by The Haworth Press, Inc. All rights reserved.

doi:10.1300/5741_a

Paul J. Bach is affiliated with Montana Neurobehavioral Specialists, Missoula, Montana.