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Anthony A. Amato - Neuromuscular Disorders

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Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs.


Copyright 2016 by McGraw-Hill Education All rights reserved Except as - photo 1

Copyright 2016 by McGraw-Hill Education. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher, with the exception that the program listings may be entered, stored, and executed in a computer system, but they may not be reproduced for publication.

ISBN: 978-0-07-175462-0

MHID: 0-07-175462-8

The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-175250-3, MHID: 0-07-175250-1.

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I want to express my gratitude to my mentors and colleagues who have taught me the art of neuromuscular medicine and continue to do so. I would be remiss if I did not thank all the patients whom I have had the honor to learn from all these years. Most of all I would like to thank and dedicate this book to my wife, Mary, and my children, Joseph, Erin, Michael, and Katie, for their unconditional love and support over the years.

Anthony A. Amato, MD

To the newest addition to our lives, Isabel Reagle Russell, in the hope that someday you will see this undertaking as a source of both pride and motivation.

James A. Russell, DO, FAAN

CONTENTS
CONTRIBUTORS

Erik Ensrud, MD
Director, Neuromuscular Center and EMG Laboratory
Boston Veterans Affairs Health Care System
Director, Neuromuscular Rehabilitation Clinic
Brigham and Womens Hospital
Boston, Massachusetts

Sabrina Paganoni, MD, PhD
Instructor in Physical Medicine and Rehabilitation
Harvard Medical School
Neurological Clinical Research Institute (NCRI)
Massachusetts General Hospital
Spaulding Rehabilitation Hospital
Boston Veterans Affairs Health Care System
Boston, Massachusetts

FOREWORD

Textbooks that have a lasting influence are rare. In neurology, such examples are Merritts Neurology and Adams and Victors Principles of Neurology, both now in print for decades and continually updated. I believe the second edition of Amato and Russells Neuromuscular Disorders is such a textbook. Immediately on the publication of the first edition, it became the primary textbook source of information for study of neuromuscular disease. Neuromuscular Disorders filled a large gap in the field. Until that time, there was no single text that covered the principles of motor neuron disease, nerve disease, neuromuscular junction disorders, and muscle disorders. Neuromuscular Disorders covers all these areas superbly. It is written primarily through the voice of two authors, Tony Amato and Jim Russell, and this provides a wonderfully consistent message and makes the book easy to read. In the second edition, there are guest authors for some specialty areas involving rehabilitative medicine, Erik Ensrud and Sabrina Paganoni, and their chapters are outstanding and the fluent voice is maintained.

The book has gained many fans because it addresses neuromuscular disorders from the clinicians perspective rather than from that of bench scientists. In addition, the book brings together muscle and nerve pathology and electrodiagnostic medicine as extensions of the clinicians approach to the patient. Readers can go to one text to find the principles of the various neuromuscular disorders and find information on pathology and neurophysiology that will enable clinicians to help their patients.

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