Dale E. Bredesen - The End of Alzheimers: the First Program to Prevent and Reverse Cognitive Decline

Praise for The End of Alzheimers

The End of Alzheimers is a monumental work. Dr. Bredesen completely recontextualizes this devastating condition away from a mysterious and unsolvable process to one that is both preventable and, yes, reversible.

D AVID P ERLMUTTER , MD, AUTHOR OF THE #1 New York Times BESTSELLERS Grain Brain AND Brain Maker

The End of Alzheimers is a masterful, authoritative, and ultimately hopeful patient guide that will help you prevent and reverse Alzheimers disease, whether you have the ApoE4 gene or not. My patients fear Alzheimers more than any other diagnosis. This is the book to transmute fear into action.

S ARA G OTTFRIED , MD, AUTHOR OF THE New York Times BESTSELLER Younger

Dr. Dale Bredesen is a world-class neuroscientist-neurologist who through his innovative and exacting research has discovered a safe and effective approach to the prevention and treatment of Alzheimers disease that will revolutionize the way we think about the disease.

J EFFREY B LAND , P H D, FOUNDER OF THE I NSTITUTE FOR F UNCTIONAL M EDICINE , THE C LEVELAND C LINIC

Dr. Bredesen has provided enormous hope for the heretofore intractable clinical problem of Alzheimers. Bredesens early studies suggest that this approach can halt and in many cases reverse early Alzheimers.

L EROY H OOD , MD, P H D, AWARDED THE N ATIONAL M EDAL OF S CIENCE , PRESENTED BY P RESIDENT B ARACK O BAMA IN 2011, AND FOUNDER OF THE I NSTITUTE FOR S YSTEMS B IOLOGY

Every citizen and medical professional interested in the brain and its health should read this seminal book. It should provide much of the basis for a true revolution in brain health medicine.

M ICHAEL M ERZENICH , P H D, WINNER OF THE 2016 K AVLI P RIZE IN N EUROSCIENCE

A must-read for anyone wondering what can be done for this dread disease, whether for themselves, a loved one, or a patient.

N ATHAN P RICE , P H D, PROFESSOR AND ASSOCIATE DIRECTOR OF THE I NSTITUTE FOR S YSTEMS B IOLOGY

Having spent several years implementing many of Dr. Bredesens insights in my patients, I can assure you that following his advice can save yourself, your loved ones, and your friends from suffering from this preventable and reversible curse.

S TEVEN G UNDRY , MD, ME DICAL DIRECTOR OF TH E I NTERNATIONAL H EAR T AND L UNG I NSTITUTE AND AUTHOR OF THE New York Times BESTSELLER The Plant Paradox

This book represents a major turning point in our approach to Alzheimers disease. For the first time ever, patients and families affected by Alzheimersas well as those at high risk for this devastating diseasetruly have a reason to be hopeful.

C HRIS K RESSER , MS, LA C , AUTHOR OF THE New York Times BESTSELLER The Paleo Cure

The End of Alzheimers offers a new beginning in medicine. Dr. Bredesen translates the knowledge of science to the wisdom that helps to heal our people... and provide a vision for the end of Alzheimers.

P ATRICK H ANAWAY , MD, FOUNDING MEDICAL DIRECTOR AN D DIRECTOR OF RESEAR CH , THE C ENTER FOR F U NCTIONAL M EDICINE , TH E C LEVELAND C LINIC

An experimental program that some patients say has literally reversed their symptoms and allowed them to live a normal life.

M ARIA S HRIVER , APPEARING ON THE Today SHOW

The End of Alzheimers, for the first time, synthesizes the latest science into a practical plan that can reverse Alzheimers and dramatically improve brain health and function. If you have a brain, read this book.

M ARK H YMAN , MD, DIRECTOR OF THE C ENTER FOR F UNCTIONAL M EDICINE , THE C LEVELAND C LINIC , AND AUTHOR OF THE #1 New York Times BESTSELLER Eat Fat, Get Thin

The End of Alzheimers is a phenomenal book. Dr. Dale Bredesens research is some of the most exciting work that I have seen in years and tackles the most important health issue of our time. This helps us understand this complex and devastating condition but is also the roadmap to prevent it in the first place. It is a must-read book. By tackling arguably the most important disease of our age, Dr. Dale Bredesen is actually changing the way we look at all chronic disease. This is a masterpiece.

R ANGAN C HATTERJEE , M B C H B, BS C (H ONS ), MRCP, MRCGP

An imprint of Penguin Random House LLC

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Copyright 2017 by Dale E. Bredesen

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Library of Congress Cataloging-in-Publication Data

Names: Bredesen, Dale E., author.

Title: The end of Alzheimers: the first program to prevent and reverse cognitive decline / Dale E. Bredesen.

Description: New York: Avery, [2017] | Includes bibliographical references and index.

Identifiers: LCCN 2017029515| ISBN 9780735216204 (hardcover: alk. paper) | ISBN 9780735216228 (epub)

Subjects: | MESH: Alzheimer Diseasetherapy | Alzheimer Diseasepsychology | Cognitive Dysfunctionprevention & control | Cognitionphysiology

Classification: LCC RC523 | NLM WT 155 | DDC 616.8/311dc23

LC record available at https://lccn.loc.gov/2017029515

Illustrations by Joe LeMonnier

Neither the publisher nor the author is engaged in rendering professional advice or services to the individual reader. The ideas, procedures, and suggestions contained in this book are not intended as a substitute for consulting with your physician. All matters regarding your health require medical supervision. Neither the author nor the publisher shall be liable or responsible for any loss or damage allegedly arising from any information or suggestion in this book.

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This book is dedicated to my wife, Dr. Aida Lasheen Bredesena superb and caring physician who introduced me to the world of functional and integrative medicine, and who has taught me more than anyone about this critical fieldand to our two beloved daughters, Tara and Tess.