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Newton - GMO Food

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1. Background and history : -- Introduction -- Modifying life: the early history -- The birth of Genetics -- The road to DNA -- The structure of DNA -- The rise of molecular genetics -- Recombinant DNA technology -- Cloning-- Transgenic plants and animals -- Practical applications of transgenic organisms -- Gene therapy and genetic testing -- Forensic DNA testing -- Recent advances in DNA technology -- Conclusion -- References.;DNA technology: a reference handbook provides an up-to-date historical overview and general technical background to the topic as well as a broad introduction to current issues related to the development of DNA technology, such as genetically modified organisms, the use of DNA technology in the forensic sciences, and genetic testing and genetic therapy. Written by David E. Newton, an author and former teacher who has dedicated a lifetime to authoring educational texts on science and technology, this book examines the history of DNA technology from its discovery in the 1950s to the present day and covers recent advances, such as new methods for gene editing, including CRISP-Cas9 technology. Readers need to have little or no background knowledge of the technology of genetic engineering to improve their understanding of DNA-based technologies and how DNA research influences many current issues and debates in agriculture, food science, forensics, public health, and other fields. The single-volume work is particularly well-suited to students and young adults because of the range of references included that serve further study, such as a glossary of terms, a chronology, and an extensive annotated bibliography--Publishers website.;2. Problems, issues, and solutions : -- Introduction -- Forensic science -- Genetically modified organisms -- Xenotransplantation-- Pharming -- Genetic testing -- Genetic counseling -- Gene therapy -- Cloning -- The double-edged sword of CRISPR technology -- Conclusion -- References.;3. Perspectives : -- Introduction -- Optogenetics / Arpita Dave -- Africans using autosomal DNA testing to find distant family members / LaKisha David -- Mandatory GMO labeling is the Right to be deceived / Jon Entine -- A brave new world for CRISPR/Cas9: Scientific limitations and ethical considerations / Rachele Hendricks-Sturrup -- Genome editing opens brave new world / Nerissa Hoglen -- Finding a face in the DNA / Clara MacCarald -- CRISPR controversies / Deirdre Manion-Fischer -- Modified DNA for targeted therapeutics / Manish Muhuri -- CRISPR and beyond -- what the future holds for gene editing / Shelia T. Yong -- Forensic use of DNA technology / Jon Zonderman.;4. Profiles : -- Introduction -- Accreditation council for genetic counseling (ACGC) -- AgBioWorld-- American board of genetic counseling (ABGC) -- American society of bioethics and humanities (ASBH) -- American society of gene and cell therapy (ASGCT) --American society of human genetics (ASHG) -- W. French Anderson (1936- ) -- Werner Arber (1929- ) -- Armed Forces DNA Identification Laboratory (AFDIL) --Association of Forensic DNA Analysts and Administrators (AFDAA) -- Oswald Avery (1877-1955) -- Paul Berg (1926- ) -- Biotechnology Innovation Organization (BIO) -- Biotechnology Regulatory Services (BRS) -- Herbert Boyer (1936- ) -- California Certified Organic Farmer (CCOF) -- Center for bioethics and human dignity (CBHD) -- Center for food safety (CFS) -- Center for genetics and society (CGS)-- Center for genomics and public health (CGPH) -- Erwin Chargaff (1905-2002) -- Emmanuelle Charpentier (1968- ) -- Mary-Dell Chilton (1939- ) -- Coalition for genetic fairness (CGF) -- Stanley N. Cohen (1935- ) -- Council for responsible genetics (CRG) -- Francis Crick (1916-2004) -- Karl Deisseroth (1971- ) -- Jennifer Doudna (1964- ) -- European NGO Network on Genetic Engineering (GENET) -- Federal Bureau of Investigation (FBI) -- Food and Agriculture Organization (FAO) --Rosalind Franklin (1920-1958) -- Genetic Alliance -- Greenpeace -- Woo-suk Hwang (1953- ) -- Innocence Project -- Institute for Responsible Technology (IRT) -- International Bioethics Committee (IBC) -- International Biopharmaceutical Association (IBPA) -- International Centre for Genetic Engineering and Biotechnology (ICGEB) -- Sir Alec Jeffreys (1950- ) -- Gregor Mendel (1822-1884) -- Johannes Friedrich Miescher (1844-1895) -- Juan Francisco Martinez Mojica (1963- ) -- Kary Mullis (1944- ) -- National Human Genome Research Institute (NHGRI) -- National Society of Genetics Counselors (NSGC) -- Marshall Nirenberg (1927-2010) -- Non-GMO Project -- Northwest Resistance against Genetic Engineering (NW RAGE) -- Office of Biotechnology Activities (OBA) -- Office of Public Health Genomics (OPHG) -- Organic Consumers Association (OCA) -- Ingo Potrykus (1933- ) -- Presidential Commission for the Study of Bioethical Issues -- Hamilton O. Smith (1931- ) -- Robert A. Swanson (1947-1999) -- DizhouTong (1902-1979) -- Union of Concerned Scientists (UCS) -- U.S. Environmental Protection Agency (EPA) -- U.S. Food and Drug Administration (FDA) -- J. Craig Venter (1946- ) -- James Watson (1928- ).;5. Data and Documents : -- Data : -- Table 5.1: Adoption of genetically engineered crops in the United States, 1996-2015 -- Table 5.2: Types of genetically engineered corn and cotton in the United States, 2000-2015 -- Table 5.3: Number of releases, sites, and constructs authorized by APHIS for evaluation -- Table 5.4: Number of releases approved by APHIS by gene trait, to September 2013 -- Table 5.6: Institutions with greatestnumber of APHIS permits for genetically engineered crops, to September 2013 -- Table 5.4: CODIS Statistics for 15 top states as of February 2016 ; -- Documents : -- Daubert v. Merrell Dow Pharmaceuticals Inc. (1993) -- Executive order 13145 (2000) -- Regulations with respect to genetically modified foods: European Union (2003) -- Alaska state law on genetic privacy (2004) -- Post-conviction DNA testing (2004) -- United Nations declaration on human cloning (2005) -- Additional protocol to the convention on human rights and biomedicine, concerning genetic testing for health purposes (2008) -- Genetic Information Nondiscrimination Act (2008) -- Vermont Act 120 (GM food labeling) (2014) -- Rule 702. Federal rules of evidence (2015) -- Grocery Manufacturers Association, et al, v. William H. Sorrell, et al. Case No. 5: 14cv-117 (2015) -- People v. Collins, NY Slip Op 25227 [49 Misc 3d 595] (2015) -- Collection and use of DNA identification information from certain federal offenders 42 U.S. Code 14135a (2016) -- Issues of DNA Collection: Maryland v. King 569 U.S. -- State v. Medina, et al. 2014 VT 69 (2014) -- 6. Annotated bibliography -- 7. Chronology.;Background and history -- Problems, issues, and solutions -- Perspectives -- Profiles -- Data and documents.

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CONTEMPORARY WORLD ISSUES

GMO Food

A REFERENCE HANDBOOK

David E. Newton

Copyright 2014 by ABC-CLIO LLC All rights reserved No part of this - photo 1

Copyright 2014 by ABC-CLIO, LLC

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, except for the inclusion of brief quotations in a review, without prior permission in writing from the publisher.

Library of Congress Cataloging-in-Publication Data

Newton, David E.

GMO food : a reference handbook / David E. Newton.

pages cm. (Contemporary world issues)

Includes bibliographical references and index.

ISBN 9781610696852 (hard copy : alk. paper) ISBN 9781610696869 (ebook) 1. Genetically modified foods. 2. Genetically modified foodsSocial aspects. 3. Genetically modified foodsRisk assessment. 4. Transgenic plants. I. Title. II. Title: Genetically modified organisms food. III. Title: Genetically modified food.

TP248.65.F66N49 2014

664dc23 2014021910

ISBN: 9781610696852

EISBN: 9781610696869

18 17 16 15 14 1 2 3 4 5

This book is also available on the World Wide Web as an eBook.

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Contents

Preface

Humans have been altering the genomes (genetic composition) of plants and animals for millennia. At first, these modifications were largely trial-and-error events in which organisms with desirable traits were crossbred with each other to produce new plants or animals better suited for food, for transportation, for working in the field, to be resistant to pests, or for other purposes. The first major breakthrough in the process of genetic modification occurred in the late nineteenth century with the discovery of the genetic units (genes) through which characteristics are transmitted from generation to generation. Breeders and biological researchers had no way of using this new knowledge, however, to improve the traditional methods of producing new organisms by crossbreeding.

The next major breakthrough, however, did cross that hurdle. In 1953, American biologist James Watson and English chemist Francis Crick showed that genes were not more nor less than chemical molecules of a substance called deoxyribonucleic acid (DNA). That discovery opened new vistas for the modification of plants and animals because DNA, like any other chemical, can be modified, at least in principle, in the same way any other chemical can be modified. For the first time in history, researchers were able to change the chemical structure of DNA from a cat, alligator, or tobacco plant, thereby producing a new type of cat, alligator, or tobacco plant. And thus was born the science of genetically modified organisms (GMOs).

Among the most obvious targets of the new technology were food organisms, plants and animals that are bred primarily as foodstuffs for humans, domestic animals, and other organisms. The technology made it possible, for example, to create new types of plants that are resistant to pesticides, making it possible to use those pesticides on crops without affecting the crops themselves. It also made possible to development of animals used for meat that are fatter or leaner, that mature more quickly, that are less susceptible to disease, or that have any one of a number of other desirable traits.

The success of this new technology is reflected in the fact that, as of 2013, 90 percent of all the cotton and corn and 93 percent of all the soybeans grown in the United States is genetically modified. Worldwide, the amount of land under cultivation for genetically modified (GM) crops has risen from essentially zero in 1996 to more than 70 million hectares (170 million acres) in developed nations and just slightly less than that amount in developing nations. Today, crops are modified for a host of purposes, including pest resistance, disease resistance, cold tolerance, drought tolerance, resistance to salinity, improved nutritional value, and the synthetic production of drugs and other useful chemical products.

Despite the undeniable success of GM crops at this point in history, critics have raised a number of concerns about the development, production, and use of such foods. Those critics often argue that, even after years of research, scientists and the general public simply do not know enough about potential health risks of GM foods. They are concerned that such foods may cause cancer in humans and other animals to whom they are fed or that they may produce allergic reactions in people who have a predisposition to such conditions. Critics also worry about the potential harm that GM foods could cause to the natural environment. They suggest that genetically engineered traits might be transferred in nature to unintended target organisms, producing frightening super-organisms, which might be resistant to human control because of their modified genomes. Critics also point out that once GM plants and animals are released to the natural environment, there may be no way to control or recover those organisms, should they turn out to be more dangerous than first thought. Finally, individuals and organizations who object to the use of GM technology fear that this technology will only make developing nations even more dependent on developed nations and multinational corporations than they already are.

This book is designed to provide young adults with the factual background they need to better understand the controversy over GM foods and with the tools to continue their own research on the topic. is a chronology of important events from prehistory to the modern day on the topic of GM food. Glossary lists important terms used in the discussion of the topic.

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