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Brunton Laurence L. - Goodman & Gilmans: The Pharmacological Basis of Therapeutics, 13th Edition

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Notice Medicine is an ever-changing science As new research and clinical - photo 1

Notice

Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs.

Copyright 2018 by McGraw-Hill Education All rights reserved Except as - photo 2

Copyright 2018 by McGraw-Hill Education. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher.

ISBN: 978-1-25-958474-9
MHID: 1-25-958474-7

The material in this eBook also appears in the print version of this title: ISBN: 978-1-25-958473-2, MHID: 1-25-958473-9.

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This is a copyrighted work and McGraw-Hill Education and its licensors reserve all rights in and to the work. Use of this work is subject to these terms. Except as permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part of it without McGraw-Hill Educations prior consent. You may use the work for your own noncommercial and personal use; any other use of the work is strictly prohibited. Your right to use the work may be terminated if you fail to comply with these terms.

THE WORK IS PROVIDED AS IS. McGRAW-HILL EDUCATION AND ITS LICENSORS MAKE NO GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR COMPLETENESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK, INCLUDING ANY INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK VIA HYPERLINK OR OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill Education and its licensors do not warrant or guarantee that the functions contained in the work will meet your requirements or that its operation will be uninterrupted or error free. Neither McGraw-Hill Education nor its licensors shall be liable to you or anyone else for any inaccuracy, error or omission, regardless of cause, in the work or for any damages resulting therefrom. McGraw-Hill Education has no responsibility for the content of any information accessed through the work. Under no circumstances shall McGraw-Hill Education and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages. This limitation of liability shall apply to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise.

In Memoriam Alfred Goodman Gilman 1941-2015 Mentor teacher researcher - photo 3

In Memoriam

Alfred Goodman Gilman

(1941-2015)

Mentor, teacher, researcher, Nobel laureate, raconteur, mensch, and longtime editor of this book

Contents

Suzanne M. Rivera and Alfred Goodman Gilman

Iain L. O. Buxton

Donald K. Blumenthal

Michelle A. Erickson and Trevor M. Penning

Kathleen M. Giacomini and Yuichi Sugiyama

Frank J. Gonzalez, Michael Coughtrie, and Robert H. Tukey

Dan M. Roden

Thomas C. Westfall, Heather Macarthur, and David P. Westfall

Joan Heller Brown, Katharina Brandl, and Jrgen Wess

Palmer Taylor

Ryan E. Hibbs and Alexander C. Zambon

Thomas C. Westfall, Heather Macarthur, and David P. Westfall

David R. Sibley, Lisa A. Hazelwood, and Susan G. Amara

R. Benjamin Free, Janet Clark, Susan Amara, and David R. Sibley

James M. ODonnell, Robert R. Bies, and Richard C. Shelton

Jonathan M. Meyer

Misty D. Smith, Cameron S. Metcalf, and Karen S. Wilcox

Erik D. Roberson

S. John Mihic, Jody Mayfield, and R. Adron Harris

Tony Yaksh and Mark Wallace

Hemal H. Patel, Matthew L. Pearn, Piyush M. Patel, and David M. Roth

William A. Catterall and Kenneth Mackie

S. John Mihic, George F. Koob, Jody Mayfield, and R. Adron Harris

Charles P. OBrien

Edwin K. Jackson

Randa Hilal-Dandan

Thomas Eschenhagen

Thomas Eschenhagen

Thomas Eschenhagen

Bjorn C. Knollmann and Dan M. Roden

Dustin R. Fraidenburg, Ankit A. Desai, and Jason X.-J. Yuan

Kerstin Hogg and Jeffrey I. Weitz

Holly E. Gurgle and Donald K. Blumenthal

Nancy Fares-Frederickson and Michael David

Alan M. Krensky, Jamil R. Azzi, and David A. Hafler

Roberto Tinoco and James E. Crowe, Jr.

Emer M. Smyth, Tilo Grosser, and Garret A. FitzGerald

Tilo Grosser, Emer M. Smyth, and Garret A. FitzGerald

Randal A. Skidgel

Peter J. Barnes

Kenneth Kaushansky and Thomas J. Kipps

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