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Yudofsky Stuart C. - Clinical Manual of Neuropsychiatry

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Clinical Manual of Neuropsychiatry focuses on the assessment, diagnosis, and treatment of the full spectrum of neuropsychiatric disorders, as well as those conditions that have significant neuropsychiatric components.With the help of this highly practical manual, clinicians are empowered to evaluate patients and treat the neuropsychiatric aspects of a host of disorders. The manual: - Sets forth a concise, step-by-step approach to assessing patients, by beginning with the indications for a neuropsychological evaluation, and progressing through the patient interview, physical examination, and measures that are useful diagnostic indicators, such as psychological testing and structural and functional neuroimaging.- Offers complete physiological and epidemiological information about each condition, by providing much-needed context and helping the clinician to identify the focal neurological symptoms to look for, potential contributing factors, and the course a disease is likely to follow.- Covers the general neuropsychiatric and neuropsychological considerations the clinician must take into account when attempting to understand the factors that influence presenting symptoms and behavioral changes. For example, intracranial pressure can be and elusive consequence of central nervous system (CNS) tumors and has been implicated in behavior changes such as apathy and depression.- Aids the clinician in making a clinical diagnosis through the precise evaluation of a patients neurological and psychiatric signs and symptoms, through taking a careful history, and through a directed physical examination the patient.- Addresses the full range of available treatment options, including psychopharmacological, psychotherapeutic, and cognitive rehabilitation modalities. - Presents an utterly up-to-date chapter on psychopharmacological treatment of patients with neuropsychiatric disorders, and includes an abundance of tables that compare indications, efficacy, and side effect profiles for the full range of drugs that are likely to be prescribed.

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Clinical Manual of
Neuropsychiatry

Clinical Manual of
Neuropsychiatry

Edited by

Stuart C. Yudofsky, M.D.
Robert E. Hales, M.D., M.B.A.

Note The authors have worked to ensure that all information in this book is - photo 1

Note: The authors have worked to ensure that all information in this book is accurate at the time of publication and consistent with general psychiatric and medical standards, and that information concerning drug dosages, schedules, and routes of administration is accurate at the time of publication and consistent with standards set by the U.S. Food and Drug Administration and the general medical community. As medical research and practice continue to advance, however, therapeutic standards may change. Moreover, specific situations may require a specific therapeutic response not included in this book. For these reasons and because human and mechanical errors sometimes occur, we recommend that readers follow the advice of physicians directly involved in their care or the care of a member of their family.

Books published by American Psychiatric Publishing (APP) represent the findings, conclusions, and views of the individual authors and do not necessarily represent the policies and opinions of APP or the American Psychiatric Association.

If you would like to buy between 25 and 99 copies of this or any other American Psychiatric Publishing title, you are eligible for a 20% discount; please contact Customer Service at appi@psych.org or 800-368-5777. If you wish to buy 100 or more copies of the same title, please e-mail us at bulksales@psych.org for a price quote.

Copyright 2012 American Psychiatric Association

ALL RIGHTS RESERVED

Manufactured in Canada on acid-free paper

15 14 13 12 11 5 4 3 2 1

First Edition

Typeset in Adobes Garamond and Formata

American Psychiatric Publishing,

a Division of American Psychiatric Association

1000 Wilson Boulevard

Arlington, VA 22209-3901

www.appi.org

Library of Congress Cataloging-in-Publication Data

Clinical manual of neuropsychiatry/edited by Stuart C. Yudofsky, Robert E. Hales.1st ed.

p. ; cm.

Includes bibliographical references and index.

ISBN 978-1-58562-429-4 (pbk.: alk. paper)

I. Yudofsky, Stuart C. II. Hales, Robert E. III. American Psychiatric Association.

[DNLM: 1. Mental Disordersphysiopathology. 2. Nervous System Diseases. WM 140]

LC classification not assigned

616.89dc23

2011032144

British Library Cataloguing in Publication Data

A CIP record is available from the British Library.

List of Tables and Figures

Neuropsychological signs and symptoms that may indicate a pathological brain process

Brain imaging modalities

Indications for imaging

Relative gray-scale appearance on a noncontrast computed tomography scan

Factors considered when choosing computed tomography (CT) or magnetic resonance imaging (MRI) examination

Signs and symptoms of delirium

DSM-IV-TR criteria for delirium due to a general medical condition

Differential diagnosis of delirium

Recommended delirium assessment instruments

Studies of delirium phenomenology

Prospective pharmacological trials in delirium

Aspects of executive functions potentially impaired after traumatic brain injury

Causes of delirium in patients with traumatic brain injury

Postconcussion syndrome

Clinical use of propranolol

Pharmacotherapy of agitation and aggression

Behavioral symptoms often associated with seizures, particularly temporal lobe epilepsy

General features of nonepileptic seizures (pseudoseizures)

Basic principles of treating patients with a seizure disorder and concomitant psychiatric symptoms

Double-blind placebo-controlled studies of poststroke depression

Distribution of intracranial tumors, by brain area, in the adult

Central nervous system conditions associated with HIV infection and AIDS

Diagnostic criteria for Alzheimers disease (AD)

Diagnostic criteria for dementia with Lewy bodies (DLB)

Diagnostic criteria for frontotemporal dementia (FTD)

Diagnostic criteria for vascular dementia (VaD)

Antidepressants

Antipsychotics/neuroleptics

Mood stabilizers

Anxiolytics and sedative-hypnotics

Cognitive agents

A normal distribution curve, showing the percentage of cases between 4 standard deviations () and +4 standard deviations (+)

Possible reasons for persistent cognitive impairment in patients after an episode of delirium

Factors associated with the psychopharmacological treatment of agitation in patients with traumatic brain injury

Mini-Mental State Examination (MMSE) scores following acute stroke in three studies among patients with major or no mood disturbance grouped according to the hemisphere of ischemia

Relative frequency of intracranial brain tumors according to location in the adult

Contributors

Liana G. Apostolova, M.D., M.S.
Associate Professor in Neurology, Mary S. Easton Center for Alzheimers Disease Research, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California

Frank Y. Chen, M.D.
Houston Adult Psychiatry, Houston, Texas

Jeffrey L. Cummings, M.D.
Augustus S. Rose Professor of Neurology; Professor of Psychiatry and Biobehavioral Neurosciences; Director, Mary S. Easton Center for Alzheimers Disease Research; Director, Deane F. Johnson Center for Neurotherapeutics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California; Director, Lou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, Nevada

Francisco Fernandez, M.D.
Professor and Chair, Department of Psychiatry and Neurosciences; Director, Institute for Research in Psychiatry, University of South Florida, Tampa, Florida

Ronald E. Fisher, M.D., Ph.D.
Assistant Professor, Departments of Radiology and Neuroscience, Baylor College of Medicine; Director of Nuclear Medicine, The Methodist Hospital, Houston, Texas

Michael D. Franzen, Ph.D.
Associate Professor of Psychiatry, Drexel University College of Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania

Brian Giunta, M.D., Ph.D.
Assistant Professor and Director, Neuroimmunology Laboratory, Department of Psychiatry and Neurosciences, University of South Florida, Tampa, Florida

Kenneth L. Goetz, M.D.
Geriatric Psychiatrist, Pittsburgh, Pennsylvania

Robert E. Hales, M.D., M.B.A.
Joe P. Tupin Professor and Chair, Department of Psychiatry and Behavioral Sciences, University of CaliforniaDavis School of Medicine, Sacramento, California; Medical Director, Sacramento County Mental Health Services; Editor-in-Chief, American Psychiatric Publishing, Inc.

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