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In memory of Kim Michele Stern
Scott Stern
For Sarah, Ben, and Amelia
Adam Cifu
In memory of my father, Robert Seidman
Diane Altkorn
Contents
Contributing Authors
Jean-Luc Benoit, MD
Associate Professor of Medicine
Section of Infectious Diseases and Global Health
University of Chicago
Chicago, Illinois
AIDS/HIV Infection
Philip Hoffman, MD
Professor of Medicine
Section of Hematology-Oncology
University of Chicago
Chicago, Illinois
Bleeding Disorders
(Coauthored with Diane Altkorn)
Matthew Kalscheur, MD
Cardiovascular Medicine Fellow
University of Wisconsin Hospital and Clinics
Madison, Wisconsin
Hypotension
(Coauthored with Scott Stern)
Wei Wei Lee, MD
Assistant Professor of Medicine
Section of General Medicine
University of Chicago
Chicago, Illinois
Sore Throat
(Coauthored with Adam Cifu)
Amber Pincavage, MD
Assistant Professor of Medicine
Section of General Medicine
University of Chicago
Chicago, Illinois
Dysuria
(Coauthored with Adam Cifu)
Elizabeth Schulwolf, MD
Assistant Professor of Medicine
Division of Hospital Medicine
Loyola University Medical Center
Maywood, Illinois
Screening and Health Maintenance
(Coauthored with Diane Altkorn)
Sachin Shah, MD
Assistant Professor of Medicine
Section of General Medicine
University of Chicago
Chicago, Illinois
Hematuria
(Coauthored with Diane Altkorn)
Sarah Stein, MD
Associate Professor of Medicine
Section of Dermatology
University of Chicago
Chicago, Illinois
Rash
(Coauthored with Adam Cifu)
Preface
Our goal in creating Symptom to Diagnosis was to develop an interesting, practical, and informative approach to teaching the diagnostic process in internal medicine. Interesting, because real patient cases are integrated within each chapter, complementing what can otherwise be dry and soporific. Informative, because Symptom to Diagnosis articulates the most difficult process in becoming a physician: making an accurate diagnosis. Many other textbooks describe diseases, but fail to characterize the process that leads from patient presentation to diagnosis. Although students can, and often do, learn this process through intuition and experience without direct instruction, we believe that diagnostic reasoning is a difficult task that can be deciphered and made easier for students. Furthermore, in many books the description of the disease is oversimplified, and the available evidence on the predictive value of symptoms, signs, and diagnostic test results is not included. Teaching based on the classic presentation often fails to help less experienced physicians recognize the common, but atypical presentation. This oversight, combined with a lack of knowledge of test characteristics, often leads to prematurely dismissing diagnoses.